Diablo | ENSMUSG00000029433 | NCBI 66593

Details for: Diablo

Gene ID: 66593

Symbol: Diablo

Ensembl ID: ENSMUSG00000029433

Description: diablo, IAP-binding mitochondrial protein

Associated with

Apoptosis
(R-MMU-109581)
Apoptotic factor-mediated response
(R-MMU-111471)
Cytochrome c-mediated apoptotic response
(R-MMU-111461)
Formation of apoptosome
(R-MMU-111458)
Intrinsic pathway for apoptosis
(R-MMU-109606)
Programmed cell death
(R-MMU-5357801)
Regulation of the apoptosome activity
(R-MMU-9627069)
Release of apoptotic factors from the mitochondria
(R-MMU-111457)
Smac(diablo)-mediated dissociation of iap:caspase complexes
(R-MMU-111464)
Smac (diablo) binds to iaps
(R-MMU-111463)
Smac, xiap-regulated apoptotic response
(R-MMU-111469)
Activation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0006919)
Activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
(GO:0008635)
Apoptotic process
(GO:0006915)
Cd40 receptor complex
(GO:0035631)
Cytoplasm
(GO:0005737)
Cytoplasmic side of plasma membrane
(GO:0009898)
Cytosol
(GO:0005829)
Intrinsic apoptotic signaling pathway
(GO:0097193)
Intrinsic apoptotic signaling pathway in response to oxidative stress
(GO:0008631)
Mitochondrial intermembrane space
(GO:0005758)
Mitochondrion
(GO:0005739)
Neuron apoptotic process
(GO:0051402)
Positive regulation of apoptotic process
(GO:0043065)
Protein binding
(GO:0005515)

Other Information

Proteins

Diablo IAP-binding mitochondrial protein, cleaved form

Genular Protein ID: 1342545940

Symbol: DBLOH_MOUSE

Name: Diablo IAP-binding mitochondrial protein, cleaved form

UniProtKB Accession Codes:

Q9JIQ3 Q542V8 Q9CZD1 Q9DCD3

Database IDs:

Citations:

PubMed ID: 10929712

Title: Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins.

PubMed ID: 10929712

DOI: 10.1016/s0092-8674(00)00009-x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15178455

Title: Direct interaction of Smac with NADE promotes TRAIL-induced apoptosis.

PubMed ID: 15178455

DOI: 10.1016/j.bbrc.2004.05.043

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23479728

Title: Identification of a novel anti-apoptotic E3 ubiquitin ligase that ubiquitinates antagonists of inhibitor of apoptosis proteins SMAC, HtrA2, and ARTS.

PubMed ID: 23479728

DOI: 10.1074/jbc.m112.436113

Sequence Information:

Length: 237
Mass: 26820
Checksum: 6961A7E76C780AC5
Sequence:

MAALRSWVTR SVCSLFRYRQ RFPVLANSKK RCFSELIKPW HKTVLTGFGM TLCAVPIAQK 
SEPQSLSNEA LMRRAVSLVT DSTSTFLSQT TYALIEAITE YTKAVYTLVS LYRQYTSLLG 
KMNSQEEDEV WQVIIGARVE MTSKQQEYLK LETTWMTAVG LSEMAAEAAY QTGADQASIT 
ARNHIQLVKS QVQEVRQLSQ KAETKLAEAQ TKELHQKAQE VSDEGADQEE EAYLRED

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Diablo

Associated with

Other Information

Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins. PubMed ID: 10929712

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

Direct interaction of Smac with NADE promotes TRAIL-induced apoptosis. PubMed ID: 15178455

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079