Details for: BOK

Gene ID: 666

Symbol: BOK

Ensembl ID: ENSG00000176720

Description: BCL2 family apoptosis regulator BOK

Associated with

  • Activation of cysteine-type endopeptidase activity involved in apoptotic process
    (GO:0006919)
  • Activation of cysteine-type endopeptidase activity involved in apoptotic process by cytochrome c
    (GO:0008635)
  • Apoptotic process
    (GO:0006915)
  • Cellular component disassembly involved in execution phase of apoptosis
    (GO:0006921)
  • Channel activity
    (GO:0015267)
  • Cis-golgi network membrane
    (GO:0033106)
  • Cytoplasm
    (GO:0005737)
  • Early endosome membrane
    (GO:0031901)
  • Endoplasmic reticulum
    (GO:0005783)
  • Endoplasmic reticulum membrane
    (GO:0005789)
  • Extrinsic apoptotic signaling pathway in absence of ligand
    (GO:0097192)
  • Golgi apparatus
    (GO:0005794)
  • Intrinsic apoptotic signaling pathway by p53 class mediator
    (GO:0072332)
  • Intrinsic apoptotic signaling pathway in response to dna damage
    (GO:0008630)
  • Male gonad development
    (GO:0008584)
  • Membrane
    (GO:0016020)
  • Mitochondrial inner membrane
    (GO:0005743)
  • Mitochondrial membrane
    (GO:0031966)
  • Mitochondrial outer membrane
    (GO:0005741)
  • Mitochondrion
    (GO:0005739)
  • Negative regulation of mitochondrial depolarization
    (GO:0051902)
  • Negative regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
    (GO:1901029)
  • Negative regulation of necroptotic process
    (GO:0060546)
  • Negative regulation of neuron apoptotic process
    (GO:0043524)
  • Neuron apoptotic process
    (GO:0051402)
  • Nuclear outer membrane
    (GO:0005640)
  • Nucleus
    (GO:0005634)
  • Oligodendrocyte differentiation
    (GO:0048709)
  • Positive regulation of apoptotic process
    (GO:0043065)
  • Positive regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
    (GO:1902237)
  • Positive regulation of execution phase of apoptosis
    (GO:1900119)
  • Positive regulation of intrinsic apoptotic signaling pathway
    (GO:2001244)
  • Positive regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
    (GO:1901030)
  • Positive regulation of perk-mediated unfolded protein response
    (GO:1903899)
  • Protein-containing complex binding
    (GO:0044877)
  • Protein binding
    (GO:0005515)
  • Protein complex oligomerization
    (GO:0051259)
  • Protein heterodimerization activity
    (GO:0046982)
  • Protein homodimerization activity
    (GO:0042803)
  • Recycling endosome membrane
    (GO:0055038)
  • Regulation of autophagy
    (GO:0010506)
  • Regulation of chorionic trophoblast cell proliferation
    (GO:1901382)
  • Regulation of cytosolic calcium ion concentration
    (GO:0051480)
  • Regulation of granulosa cell apoptotic process
    (GO:1904708)
  • Release of cytochrome c from mitochondria
    (GO:0001836)
  • Signaling receptor binding
    (GO:0005102)
  • Trans-golgi network membrane
    (GO:0032588)
  • Ubiquitin protein ligase binding
    (GO:0031625)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 26.4550
    Cell Significance Index: -12.4900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 3.0933
    Cell Significance Index: -6.7700
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: 1.1888
    Cell Significance Index: 16.2200
  • Cell Name: pulmonary interstitial fibroblast (CL0002241)
    Fold Change: 0.7694
    Cell Significance Index: 4.7600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: 0.6741
    Cell Significance Index: 35.0200
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.6423
    Cell Significance Index: 38.5600
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.5988
    Cell Significance Index: 59.2300
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.5901
    Cell Significance Index: 117.1100
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 0.5125
    Cell Significance Index: 13.9500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 0.4543
    Cell Significance Index: 410.1900
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.3342
    Cell Significance Index: 45.8900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: 0.3131
    Cell Significance Index: 5.1600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.3030
    Cell Significance Index: 49.2800
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 0.2902
    Cell Significance Index: 128.3000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.2886
    Cell Significance Index: 6.3200
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.2462
    Cell Significance Index: 18.3500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.2420
    Cell Significance Index: 132.1600
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2285
    Cell Significance Index: 15.8000
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2205
    Cell Significance Index: 41.9600
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 0.2144
    Cell Significance Index: 27.7000
  • Cell Name: subcutaneous adipocyte (CL0002521)
    Fold Change: 0.1516
    Cell Significance Index: 0.6600
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 0.1500
    Cell Significance Index: 6.8000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 0.1418
    Cell Significance Index: 6.6700
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 0.1233
    Cell Significance Index: 8.7200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.1139
    Cell Significance Index: 78.7500
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.1104
    Cell Significance Index: 3.1800
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 0.1028
    Cell Significance Index: 12.6400
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 0.0725
    Cell Significance Index: 13.0800
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0711
    Cell Significance Index: 1.5400
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0516
    Cell Significance Index: 10.3500
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0496
    Cell Significance Index: 17.7800
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: 0.0325
    Cell Significance Index: 0.2000
  • Cell Name: luminal cell of prostate epithelium (CL0002340)
    Fold Change: 0.0261
    Cell Significance Index: 0.2700
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.0250
    Cell Significance Index: 18.9000
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.0152
    Cell Significance Index: 0.3800
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0122
    Cell Significance Index: 2.0900
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: 0.0085
    Cell Significance Index: 0.3000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: -0.0048
    Cell Significance Index: -9.1200
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.0054
    Cell Significance Index: -0.0900
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0078
    Cell Significance Index: -14.3800
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0090
    Cell Significance Index: -13.8800
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0111
    Cell Significance Index: -8.1100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0114
    Cell Significance Index: -15.5400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0168
    Cell Significance Index: -10.6800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0175
    Cell Significance Index: -12.9300
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0210
    Cell Significance Index: -11.8200
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0226
    Cell Significance Index: -14.1300
  • Cell Name: adipocyte of breast (CL0002617)
    Fold Change: -0.0274
    Cell Significance Index: -0.3500
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0294
    Cell Significance Index: -13.3500
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0294
    Cell Significance Index: -3.7700
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.0299
    Cell Significance Index: -8.6200
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.0328
    Cell Significance Index: -2.0100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0371
    Cell Significance Index: -4.2500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0381
    Cell Significance Index: -4.4400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0404
    Cell Significance Index: -1.1300
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0575
    Cell Significance Index: -2.6800
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0624
    Cell Significance Index: -1.3300
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0626
    Cell Significance Index: -9.1000
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0664
    Cell Significance Index: -4.0800
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0710
    Cell Significance Index: -14.9600
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0727
    Cell Significance Index: -7.4300
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.0939
    Cell Significance Index: -1.5800
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -0.1050
    Cell Significance Index: -3.6500
  • Cell Name: oligodendrocyte (CL0000128)
    Fold Change: -0.1147
    Cell Significance Index: -1.2300
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.1158
    Cell Significance Index: -12.0600
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.1250
    Cell Significance Index: -2.1100
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.1251
    Cell Significance Index: -2.8900
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1352
    Cell Significance Index: -10.7100
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1568
    Cell Significance Index: -8.8000
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.1651
    Cell Significance Index: -2.8300
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.1654
    Cell Significance Index: -12.6900
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.1788
    Cell Significance Index: -11.2700
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.1843
    Cell Significance Index: -12.3900
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.1863
    Cell Significance Index: -8.1000
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.1873
    Cell Significance Index: -6.0000
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2013
    Cell Significance Index: -5.7700
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2050
    Cell Significance Index: -13.2300
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.2130
    Cell Significance Index: -3.2100
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.2247
    Cell Significance Index: -11.8000
  • Cell Name: granulocyte monocyte progenitor cell (CL0000557)
    Fold Change: -0.2385
    Cell Significance Index: -2.6700
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: -0.2388
    Cell Significance Index: -3.5300
  • Cell Name: corneal epithelial cell (CL0000575)
    Fold Change: -0.2445
    Cell Significance Index: -3.4800
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.2650
    Cell Significance Index: -11.7200
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.2693
    Cell Significance Index: -7.1900
  • Cell Name: early T lineage precursor (CL0002425)
    Fold Change: -0.2817
    Cell Significance Index: -4.0900
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2912
    Cell Significance Index: -10.6900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.2981
    Cell Significance Index: -8.7800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.2995
    Cell Significance Index: -11.3400
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: -0.3053
    Cell Significance Index: -5.4000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.3206
    Cell Significance Index: -11.2300
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.3241
    Cell Significance Index: -7.8500
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.3284
    Cell Significance Index: -5.2100
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.3287
    Cell Significance Index: -10.4700
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: -0.3316
    Cell Significance Index: -6.9400
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -0.3348
    Cell Significance Index: -8.9700
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: -0.3350
    Cell Significance Index: -8.8100
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3478
    Cell Significance Index: -8.9400
  • Cell Name: epithelial cell of uterus (CL0002149)
    Fold Change: -0.3532
    Cell Significance Index: -4.9000
  • Cell Name: keratinocyte (CL0000312)
    Fold Change: -0.3593
    Cell Significance Index: -8.9800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.3781
    Cell Significance Index: -12.3800

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** BOK is a protein-coding gene that encodes a BCL2-like protein, which belongs to the BCL2 family of proteins. These proteins are involved in regulating apoptosis, and their dysregulation can lead to various diseases, including cancer and neurodegenerative disorders. BOK is characterized by its ability to bind to other proteins, such as BCL2 and BAX, to modulate their activity and regulate apoptosis. Its expression is widespread, with significant levels found in immune cells, neurons, and epithelial cells. **Pathways and Functions:** BOK is involved in various cellular processes, including apoptosis, autophagy, and cellular stress response. Its functions can be summarized as follows: 1. **Apoptosis regulation:** BOK modulates the activity of caspases, enzymes responsible for executing cell death, to regulate apoptosis. 2. **Negative regulation of apoptosis:** BOK interacts with pro-apoptotic proteins, such as BAX and BAK, to inhibit their activity and prevent excessive cell death. 3. **Positive regulation of autophagy:** BOK can regulate autophagy, a process of cellular self-digestion, to maintain cellular homeostasis. 4. **Negative regulation of necroptosis:** BOK can inhibit necroptosis, a form of programmed cell death, to prevent excessive cell death. 5. **Regulation of cellular stress response:** BOK can regulate the response to cellular stress, such as endoplasmic reticulum stress, to maintain cellular homeostasis. **Clinical Significance:** Dysregulation of BOK has been implicated in various diseases, including: 1. **Cancer:** BOK dysregulation can contribute to cancer development and progression by promoting excessive cell growth and preventing apoptosis. 2. **Neurodegenerative disorders:** BOK dysregulation has been implicated in neurodegenerative disorders, such as Alzheimer's disease and Parkinson's disease, by promoting excessive cell death and neuronal dysfunction. 3. **Immune disorders:** BOK dysregulation can contribute to immune disorders, such as autoimmune diseases, by promoting excessive cell death and immune dysfunction. In conclusion, the BOK gene plays a crucial role in regulating apoptosis and cellular homeostasis. Its dysregulation can contribute to various diseases, highlighting the importance of understanding its functions and mechanisms of action. Further research is needed to fully elucidate the role of BOK in human disease and to develop therapeutic strategies to target its dysregulation.

Genular Protein ID: 4252464404

Symbol: BOK_HUMAN

Name: Bcl-2-like protein 9

UniProtKB Accession Codes:

Q9UMX3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 3 Ensembl 1 ExpressionAtlas 1 GO 47 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MINT 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PRINTS 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TCDB 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 11034351

Title: Evolutionarily conserved Bok proteins in the Bcl-2 family.

PubMed ID: 11034351

DOI: 10.1016/s0014-5793(00)01921-9

PubMed ID: 15775999

Title: A novel Mtd splice isoform is responsible for trophoblast cell death in pre-eclampsia.

PubMed ID: 15775999

DOI: 10.1038/sj.cdd.4401593

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9535847

Title: Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-XL.

PubMed ID: 9535847

DOI: 10.1074/jbc.273.15.8705

PubMed ID: 15102863

Title: BOK and NOXA are essential mediators of p53-dependent apoptosis.

PubMed ID: 15102863

DOI: 10.1074/jbc.m313526200

PubMed ID: 15868100

Title: Membrane translocation and oligomerization of hBok are triggered in response to apoptotic stimuli and Bnip3.

PubMed ID: 15868100

DOI: 10.1007/s00018-005-4543-3

PubMed ID: 16302269

Title: Nuclear translocation of the pro-apoptotic Bcl-2 family member Bok induces apoptosis.

PubMed ID: 16302269

DOI: 10.1002/mc.20156

PubMed ID: 19690332

Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.

PubMed ID: 19690332

DOI: 10.1126/scisignal.2000007

PubMed ID: 19942931

Title: Mtd/Bok takes a swing: proapoptotic Mtd/Bok regulates trophoblast cell proliferation during human placental development and in preeclampsia.

PubMed ID: 19942931

DOI: 10.1038/cdd.2009.167

PubMed ID: 20673843

Title: Regulation of cell death in human fetal and adult ovaries--role of Bok and Bcl-X(L).

PubMed ID: 20673843

DOI: 10.1016/j.mce.2010.07.020

PubMed ID: 24113155

Title: Placental autophagy regulation by the BOK-MCL1 rheostat.

PubMed ID: 24113155

DOI: 10.4161/auto.26452

PubMed ID: 23884412

Title: The Bcl-2 protein family member Bok binds to the coupling domain of inositol 1,4,5-trisphosphate receptors and protects them from proteolytic cleavage.

PubMed ID: 23884412

DOI: 10.1074/jbc.m113.496570

PubMed ID: 27076518

Title: Bok is a genuine multi-BH-domain protein that triggers apoptosis in the absence of Bax and Bak.

PubMed ID: 27076518

DOI: 10.1242/jcs.181727

Sequence Information:

  • Length: 212
  • Mass: 23280
  • Checksum: 053ED605FF8EF5B2
  • Sequence:
    • MEVLRRSSVF AAEIMDAFDR SPTDKELVAQ AKALGREYVH ARLLRAGLSW SAPERAAPVP 
GRLAEVCAVL LRLGDELEMI RPSVYRNVAR QLHISLQSEP VVTDAFLAVA GHIFSAGITW 
GKVVSLYAVA AGLAVDCVRQ AQPAMVHALV DCLGEFVRKT LATWLRRRGG WTDVLKCVVS 
TDPGLRSHWL VAALCSFGRF LKAAFFVLLP ER

Genular Protein ID: 3920721375

Symbol: A0A481T0W6_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A481T0W6

Database IDs:

AlphaFoldDB 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 2 GO 6 Gene3D 1 InterPro 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PeptideAtlas 1 RefSeq 1 SUPFAM 1

Sequence Information:

  • Length: 117
  • Mass: 12869
  • Checksum: ADA05B252CC084C4
  • Sequence:
    • MEVLRRSSVF AAEIMDAFDR SPTDKELVAQ AKALGREYVH ARLLRAGLSW SAPERAAPVP 
GRLAEVCAVL LRLGDELEMI RPSVYRNVAR QLHISLQSEP VVTDAFLAVA GHIFSAD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.