Ormdl3 | ENSMUSG00000038150 | NCBI 66612

Details for: Ormdl3

Gene ID: 66612

Symbol: Ormdl3

Ensembl ID: ENSMUSG00000038150

Description: ORM1-like 3 (S. cerevisiae)

Associated with

Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metabolism
(R-MMU-1430728)
Metabolism of lipids
(R-MMU-556833)
Neutrophil degranulation
(R-MMU-6798695)
Sphingolipid de novo biosynthesis
(R-MMU-1660661)
Sphingolipid metabolism
(R-MMU-428157)
Ceramide metabolic process
(GO:0006672)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Intracellular sphingolipid homeostasis
(GO:0090156)
Membrane
(GO:0016020)
Molecular_function
(GO:0003674)
Motor behavior
(GO:0061744)
Myelination
(GO:0042552)
Negative regulation of b cell apoptotic process
(GO:0002903)
Negative regulation of ceramide biosynthetic process
(GO:1900060)
Negative regulation of serine c-palmitoyltransferase activity
(GO:1904221)
Positive regulation of autophagy
(GO:0010508)
Positive regulation of protein localization to nucleus
(GO:1900182)
Regulation of ceramide biosynthetic process
(GO:2000303)
Regulation of smooth muscle contraction
(GO:0006940)
Regulation of sphingolipid biosynthetic process
(GO:0090153)
Sphingolipid biosynthetic process
(GO:0030148)
Sphingomyelin biosynthetic process
(GO:0006686)
Spots complex
(GO:0035339)

Other Information

Proteins

ORM1-like protein 3

Genular Protein ID: 662088270

Symbol: ORML3_MOUSE

Name: ORM1-like protein 3

UniProtKB Accession Codes:

Q9CPZ6 A2A4X7 Q8BN65 Q8R0U5

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 31880535

Title: The Ormdl genes regulate the sphingolipid synthesis pathway to ensure proper myelination and neurologic function in mice.

PubMed ID: 31880535

DOI: 10.7554/elife.51067

PubMed ID: 30700557

Title: The ORMDL/Orm-serine palmitoyltransferase (SPT) complex is directly regulated by ceramide: Reconstitution of SPT regulation in isolated membranes.

PubMed ID: 30700557

DOI: 10.1074/jbc.ra118.007291

Sequence Information:

Length: 153
Mass: 17477
Checksum: E37EB8D0E958EB2D
Sequence:

MNVGTAHSEV NPNTRVMNSR GIWLSYVLAI GLLHVVLLSI PFVSVPVVWT LTNLIHNLGM 
YIFLHTVKGT PFETPDQGKA RLLTHWEQMD YGVQFTASRK FLTITPIVLY FLTSFYTKYD 
QVHFILNTVS LMTVLIPKLP QLHGVRIFGI NKY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ormdl3

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334