Details for: Pnpla2
Associated with
Other Information
Genular Protein ID: 807921745
Symbol: PLPL2_MOUSE
Name: Adipose triglyceride lipase
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15337759
Title: Desnutrin, an adipocyte gene encoding a novel patatin domain-containing protein, is induced by fasting and glucocorticoids: ectopic expression of desnutrin increases triglyceride hydrolysis.
PubMed ID: 15337759
PubMed ID: 15550674
Title: Fat mobilization in adipose tissue is promoted by adipose triglyceride lipase.
PubMed ID: 15550674
PubMed ID: 16705060
Title: The adipose tissue triglyceride lipase ATGL/PNPLA2 is downregulated by insulin and TNF-alpha in 3T3-L1 adipocytes and is a target for transactivation by PPARgamma.
PubMed ID: 16705060
PubMed ID: 16141072
Title: The transcriptional landscape of the mammalian genome.
PubMed ID: 16141072
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9798653
Title: Expressed genes in interleukin-4 treated B cells identified by cDNA representational difference analysis.
PubMed ID: 9798653
PubMed ID: 16150821
Title: Expression, regulation, and triglyceride hydrolase activity of Adiponutrin family members.
PubMed ID: 16150821
PubMed ID: 16009485
Title: Isoproterenol, TNFalpha, and insulin downregulate adipose triglyceride lipase in 3T3-L1 adipocytes.
PubMed ID: 16009485
PubMed ID: 16679289
Title: Adipose triglyceride lipase-mediated lipolysis of cellular fat stores is activated by CGI-58 and defective in Chanarin-Dorfman Syndrome.
PubMed ID: 16679289
PubMed ID: 16380488
Title: Adipose triglyceride lipase: function, regulation by insulin, and comparison with adiponutrin.
PubMed ID: 16380488
PubMed ID: 17074755
Title: Adipose triglyceride lipase and hormone-sensitive lipase are the major enzymes in adipose tissue triacylglycerol catabolism.
PubMed ID: 17074755
PubMed ID: 16675698
Title: Defective lipolysis and altered energy metabolism in mice lacking adipose triglyceride lipase.
PubMed ID: 16675698
PubMed ID: 17114792
Title: Control of adipose triglyceride lipase action by serine 517 of perilipin A globally regulates protein kinase A-stimulated lipolysis in adipocytes.
PubMed ID: 17114792
PubMed ID: 17189257
Title: Analysis of lipolytic protein trafficking and interactions in adipocytes.
PubMed ID: 17189257
PubMed ID: 21183079
Title: A tissue-specific atlas of mouse protein phosphorylation and expression.
PubMed ID: 21183079
PubMed ID: 21148142
Title: Interactions of perilipin-5 (Plin5) with adipose triglyceride lipase.
PubMed ID: 21148142
PubMed ID: 21393244
Title: Unique regulation of adipose triglyceride lipase (ATGL) by perilipin 5, a lipid droplet-associated protein.
PubMed ID: 21393244
PubMed ID: 22733971
Title: Identification and functional characterization of protein kinase A phosphorylation sites in the major lipolytic protein, adipose triglyceride lipase.
PubMed ID: 22733971
DOI: 10.1210/en.2012-1127
PubMed ID: 23066022
Title: Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.
PubMed ID: 23066022
PubMed ID: 35676490
Title: ATGL is a biosynthetic enzyme for fatty acid esters of hydroxy fatty acids.
PubMed ID: 35676490
Sequence Information:
- Length: 486
- Mass: 53657
- Checksum: 512FE1931B72FC9C
- Sequence:
MFPRETKWNI SFAGCGFLGV YHIGVASCLR EHAPFLVANA THIYGASAGA LTATALVTGA CLGEAGANII EVSKEARKRF LGPLHPSFNL VKTIRGCLLK TLPADCHERA NGRLGISLTR VSDGENVIIS HFSSKDELIQ ANVCSTFIPV YCGLIPPTLQ GVRYVDGGIS DNLPLYELKN TITVSPFSGE SDICPQDSST NIHELRVTNT SIQFNLRNLY RLSKALFPPE PMVLREMCKQ GYRDGLRFLR RNGLLNQPNP LLALPPVVPQ EEDAEEAAVV EERAGEEDQL QPYRKDRILE HLPARLNEAL LEACVEPKDL MTTLSNMLPV RLATAMMVPY TLPLESAVSF TIRLLEWLPD VPEDIRWMKE QTGSICQYLV MRAKRKLGDH LPSRLSEQVE LRRAQSLPSV PLSCATYSEA LPNWVRNNLS LGDALAKWEE CQRQLLLGLF CTNVAFPPDA LRMRAPASPT AADPATPQDP PGLPPC
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.