Details for: Dnajc10

Gene ID: 66861

Symbol: Dnajc10

Ensembl ID: ENSMUSG00000027006

Description: DnaJ heat shock protein family (Hsp40) member C10

Associated with

  • Atpase activator activity
    (GO:0001671)
  • Atpase binding
    (GO:0051117)
  • Disulfide oxidoreductase activity
    (GO:0015036)
  • Endoplasmic reticulum
    (GO:0005783)
  • Endoplasmic reticulum chaperone complex
    (GO:0034663)
  • Endoplasmic reticulum lumen
    (GO:0005788)
  • Hsp70 protein binding
    (GO:0030544)
  • Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress
    (GO:0070059)
  • Ire1-mediated unfolded protein response
    (GO:0036498)
  • Misfolded protein binding
    (GO:0051787)
  • Negative regulation of protein phosphorylation
    (GO:0001933)
  • Oxidoreductase activity
    (GO:0016491)
  • Oxidoreductase activity, acting on a sulfur group of donors, disulfide as acceptor
    (GO:0016671)
  • Positive regulation of atp-dependent activity
    (GO:0032781)
  • Protein-disulfide reductase activity
    (GO:0015035)
  • Protein-folding chaperone binding
    (GO:0051087)
  • Protein binding
    (GO:0005515)
  • Protein folding in endoplasmic reticulum
    (GO:0034975)
  • Response to endoplasmic reticulum stress
    (GO:0034976)

Other Information

Genular Protein ID: 808489560

Symbol: DJC10_MOUSE

Name: DnaJ homolog subfamily C member 10

UniProtKB Accession Codes:

Q9DC23 A2ASA2 Q71S84 Q8CH78 Q8CIB0 Q99LV4

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 3 CTD 1 ChiTaRS 1 DNASU 1 EC 1 EMBL 6 EPD 1 Ensembl 1 EvolutionaryTrace 1 GO 18 Gene3D 2 GeneTree 1 Genevisible 1 GlyCosmos 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 8 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 10 PDBsum 5 PIRSF 1 PRINTS 1 PRO 1 PROSITE 4 PROSITE-ProRule 3 PaxDb 1 PeptideAtlas 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 2 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 2 iPTMnet 1

Citations:

PubMed ID: 12411443

Title: ERdj5, an endoplasmic reticulum (ER)-resident protein containing DnaJ and thioredoxin domains, is expressed in secretory cells or following ER stress.

PubMed ID: 12411443

DOI: 10.1074/jbc.m206995200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12446677

Title: JPDI, a novel endoplasmic reticulum-resident protein containing both a BiP-interacting J-domain and thioredoxin-like motifs.

PubMed ID: 12446677

DOI: 10.1074/jbc.m208346200

PubMed ID: 18653895

Title: ERdj5 is required as a disulfide reductase for degradation of misfolded proteins in the ER.

PubMed ID: 18653895

DOI: 10.1126/science.1159293

PubMed ID: 19788412

Title: Positive contribution of ERdj5/JPDI to endoplasmic reticulum protein quality control in the salivary gland.

PubMed ID: 19788412

DOI: 10.1042/bj20091269

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21329881

Title: Structural basis of an ERAD pathway mediated by the ER-resident protein disulfide reductase ERdj5.

PubMed ID: 21329881

DOI: 10.1016/j.molcel.2011.01.021

Sequence Information:

  • Length: 793
  • Mass: 90583
  • Checksum: 00C88EF3F5497BE1
  • Sequence:
    • MGVWLNKDDF IRDLKRISLC LLILYVVVVV GTDQNFYSLL GVSKTASSRE IRQAFKKLAL 
KLHPDKNPNN PNAHGDFLKI NRAYEVLKDE DLRKKYDKYG EKGLEDNQGG QYESWSYYRY 
DFGIYDDDPE IITLERREFD AAVNSGELWF VNFYSPGCSH CHDLAPTWRE FAKEVDGLLR 
IGAVNCGDDR MLCRMKGVNS YPSLFIFRSG MAAVKYNGDR SKESLVAFAM QHVRSTVTEL 
STGNFVNAIE TAFAAGVGWL ITFCSKGEDC LTSQTRLRLS GMLDGLVNVG WVDCDAQDSL 
CKSLDTTAST TAYFPPGATL NDREKSSVLF LNSLDAKEIY MEIIHNLPDF ELLSANQLED 
RLAHHRWLVF FHFGKNENAN DPELKKLKTL LKNEHIQVGR FDCSSAPGIC SDLYVFQPCL 
AVFKGQGTKE YEIHHGKKIL YDILAFAKES VNSHVTTLGP QNFPASDKEP WLVDFFAPWC 
PPCRALLPEL RKASTLLYGQ LKVGTLDCTI HEGLCNMYNI QAYPTTVVFN QSSIHEYEGH 
HSAEQILEFI EDLRNPSVVS LTPSTFNELV KQRKHDEVWM VDFYSPWCHP CQVLMPEWKR 
MARTLTGLIN VGSVDCQQYH SFCTQENVQR YPEIRFYPQK SSKAYQYHSY NGWNRDAYSL 
RSWGLGFLPQ ASIDLTPQTF NEKVLQGKTH WVVDFYAPWC GPCQNFAPEF ELLARMIKGK 
VRAGKVDCQA YPQTCQKAGI KAYPSVKLYQ YERAKKSIWE EQINSRDAKT IAALIYGKLE 
TLQSQVKRNK DEL

Genular Protein ID: 637211283

Symbol: Q9CUG0_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9CUG0

Database IDs:

AGR 1 ARBA 2 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 2 GO 1 Gene3D 2 Genevisible 1 InterPro 4 KEGG 1 MGI 2 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 PeptideAtlas 1 Pfam 2 RefSeq 1 SAM 1 SMART 1 SUPFAM 2 UCSC 1

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

  • Length: 182
  • Mass: 21133
  • Checksum: 1F245F58B27333FD
  • Sequence:
    • MGVWLNKDDF IRDLKRISLC LLILYVVVVV GTDQNFYSLL GVSKTASSRE IRQAFKKLAL 
KLHPDKNPNN PNAHGDFLKI NRAYEVLKDE DLRKKYDKYG EKGLEDNQGG QYESWSYYRY 
DFGIYDDDPE IITLERREFD AAVNSGELWF VNFYSPGCSH CHDLAPTVRM FNNPAIKAFF 
LV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.