Sdha | ENSMUSG00000021577 | NCBI 66945

Details for: Sdha

Gene ID: 66945

Symbol: Sdha

Ensembl ID: ENSMUSG00000021577

Description: succinate dehydrogenase complex, subunit A, flavoprotein (Fp)

Associated with

Citric acid cycle (tca cycle)
(R-MMU-71403)
Metabolism
(R-MMU-1430728)
Pyruvate metabolism and citric acid (tca) cycle
(R-MMU-71406)
The citric acid (tca) cycle and respiratory electron transport
(R-MMU-1428517)
Electron transfer activity
(GO:0009055)
Electron transport chain
(GO:0022900)
Flavin adenine dinucleotide binding
(GO:0050660)
Membrane
(GO:0016020)
Mitochondrial electron transport, succinate to ubiquinone
(GO:0006121)
Mitochondrial inner membrane
(GO:0005743)
Mitochondrial respiratory chain complex ii, succinate dehydrogenase complex (ubiquinone)
(GO:0005749)
Mitochondrion
(GO:0005739)
Myelin sheath
(GO:0043209)
Nervous system development
(GO:0007399)
Nucleolus
(GO:0005730)
Oxidoreductase activity
(GO:0016491)
Oxidoreductase activity, acting on the ch-ch group of donors
(GO:0016627)
Proton motive force-driven mitochondrial atp synthesis
(GO:0042776)
Respiratory electron transport chain
(GO:0022904)
Succinate dehydrogenase (quinone) activity
(GO:0008177)
Succinate dehydrogenase activity
(GO:0000104)
Succinate dehydrogenase complex (ubiquinone)
(GO:0045257)
Succinate metabolic process
(GO:0006105)
Tricarboxylic acid cycle
(GO:0006099)

Other Information

Proteins

Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

Genular Protein ID: 1292667562

Symbol: SDHA_MOUSE

Name: Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial

UniProtKB Accession Codes:

Q8K2B3 Q0QF19 Q3UH25 Q3UKP7 Q3V4B1 Q921P5 Q9Z1Z4

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16751257

Title: Housekeeping genes for phylogenetic analysis of eutherian relationships.

PubMed ID: 16751257

DOI: 10.1093/molbev/msl027

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21858060

Title: Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity.

PubMed ID: 21858060

DOI: 10.1371/journal.pone.0023295

PubMed ID: 23806337

Title: SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways.

PubMed ID: 23806337

DOI: 10.1016/j.molcel.2013.06.001

PubMed ID: 23576753

Title: Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways.

PubMed ID: 23576753

DOI: 10.1073/pnas.1302961110

Sequence Information:

Length: 664
Mass: 72585
Checksum: DDCE1535163C9449
Sequence:

MAGVGAVSRL LRGRRLALTG AWPGTLQKQT CGFHFSVGEN KKASAKVSDA ISTQYPVVDH 
EFDAVVVGAG GAGLRAAFGL SEAGFNTACL TKLFPTRSHT VAAQGGINAA LGNMEEDNWR 
WHFYDTVKGS DWLGDQDAIH YMTEQAPASV VELENYGMPF SRTEDGKIYQ RAFGGQSLKF 
GKGGQAHRCC CVADRTGHSL LHTLYGRSLR YDTSYFVEYF ALDLLMENGE CRGVIALCIE 
DGSIHRIRAK NTVIATGGYG RTYFSCTSAH TSTGDGTAMV TRAGLPCQDL EFVQFHPTGI 
YGAGCLITEG CRGEGGILIN SQGERFMERY APVAKDLASR DVVSRSMTLE IREGRGCGPE 
KDHVYLQLHH LPPEQLATRL PGISETAMIF AGVDVTKEPI PVLPTVHYNM GGIPTNYKGQ 
VLKHVNGQDQ IVPGLYACGE AACASVHGAN RLGANSLLDL VVFGRACALS IAESCRPGDK 
VPSIKANAGE ESVMNLDKLR FADGSIRTSE LRLNMQKSMQ NHAAVFRVGS VLQEGCEKIS 
QLYGDLKHLK TFDRGMVWNT DLVETLELQN LMLCALQTIY GAEARKESRG AHAREDYKVR 
VDEYDYSKPI QGQQKKPFGE HWRKHTLSYV DIKTGKVTLE YRPVIDKTLN EADCATVPPA 
IRSY

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Sdha

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Housekeeping genes for phylogenetic analysis of eutherian relationships. PubMed ID: 16751257

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Succinate dehydrogenase is a direct target of sirtuin 3 deacetylase activity. PubMed ID: 21858060

SIRT5-mediated lysine desuccinylation impacts diverse metabolic pathways. PubMed ID: 23806337

Label-free quantitative proteomics of the lysine acetylome in mitochondria identifies substrates of SIRT3 in metabolic pathways. PubMed ID: 23576753