Cdk5rap1 | ENSMUSG00000027487 | NCBI 66971

Details for: Cdk5rap1

Gene ID: 66971

Symbol: Cdk5rap1

Ensembl ID: ENSMUSG00000027487

Description: CDK5 regulatory subunit associated protein 1

Associated with

4 iron, 4 sulfur cluster binding
(GO:0051539)
Catalytic activity
(GO:0003824)
Cytosol
(GO:0005829)
Iron-sulfur cluster binding
(GO:0051536)
Metal ion binding
(GO:0046872)
Methylthiotransferase activity
(GO:0035596)
Mitochondrial trna modification
(GO:0070900)
Mitochondrion
(GO:0005739)
N6-isopentenyladenosine methylthiotransferase activity
(GO:0035597)
Negative regulation of cyclin-dependent protein serine/threonine kinase activity
(GO:0045736)
Nucleoplasm
(GO:0005654)
Positive regulation of mitochondrial translation
(GO:0070131)
Positive regulation of translational fidelity
(GO:0045903)
Protein-containing complex binding
(GO:0044877)
Transferase activity
(GO:0016740)
Trna modification
(GO:0006400)
Trna processing
(GO:0008033)

Other Information

Proteins

CDK5 activator-binding protein C42

Genular Protein ID: 1450142266

Symbol: CK5P1_MOUSE

Name: CDK5 activator-binding protein C42

UniProtKB Accession Codes:

Q8BTW8 Q9D6Q4

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 25738458

Title: Cdk5rap1-mediated 2-methylthio modification of mitochondrial tRNAs governs protein translation and contributes to myopathy in mice and humans.

PubMed ID: 25738458

DOI: 10.1016/j.cmet.2015.01.019

Sequence Information:

Length: 588
Mass: 66110
Checksum: 4430C4F1A067093C
Sequence:

MHPLRCVLQV QRLSAPFTSM CWVLLRTCRA QSSVSSTPCP SPEAKSSEAQ KDFSSRLATG 
PTFQHFLRSA SVPQEKPSSP EVEDPPPYLS GDELLGRQRK VYLETYGCQM NVNDTEIAWS 
ILQKSGYLRT SNLQEADVIL LVTCSIREKA EQTIWNRLHQ LKVLKTKRPR SRVPLRIGIL 
GCMAERLKGE ILNREKMVDL LAGPDAYRDL PRLLAVVESG QQAANVLLSL DETYADIMPV 
QTSPSATSAF VSIMRGCDNM CSYCIVPFTR GRERSRPVAS ILDEVRKLSE QGLKEVTLLG 
QNVNSFRDNS EVQFNNAGSA NLSRGFTTNY KPKQGGLRFS HLLDQVSRID PEMRIRFTSP 
HPKDFPDEVL QLIRERHNIC KQIHLPAQSG SSRVLDAMRR GYSREAYVAL VHHVRETIPG 
VSLSSDFITG FCGETEDDHR QTVSLLREVQ YNTGFLFAYS MRQKTRAYHR LKDDVPEEVK 
LRRLEELITV FREEASKANK TSVGCSQLVL VEGFSKRSTT DLCGRNDANL KVIFPDAEVE 
DITNPGLKVR AQPGDYVLVK ITSASSQTLK GHILCRTTMK DSLTYCTT

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.