Ndc80 | ENSMUSG00000024056 | NCBI 67052

Details for: Ndc80

Gene ID: 67052

Symbol: Ndc80

Ensembl ID: ENSMUSG00000024056

Description: NDC80 kinetochore complex component

Associated with

Amplification of signal from the kinetochores
(R-MMU-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-MMU-141444)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Eml4 and nudc in mitotic spindle formation
(R-MMU-9648025)
Mitotic anaphase
(R-MMU-68882)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prometaphase
(R-MMU-68877)
Mitotic spindle checkpoint
(R-MMU-69618)
M phase
(R-MMU-68886)
Resolution of sister chromatid cohesion
(R-MMU-2500257)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate formins
(R-MMU-5663220)
Separation of sister chromatids
(R-MMU-2467813)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Attachment of mitotic spindle microtubules to kinetochore
(GO:0051315)
Attachment of spindle microtubules to kinetochore
(GO:0008608)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Centrosome
(GO:0005813)
Centrosome duplication
(GO:0051298)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Chromosome segregation
(GO:0007059)
Cyclin binding
(GO:0030332)
Cytoplasm
(GO:0005737)
Establishment of mitotic spindle orientation
(GO:0000132)
G2/mi transition of meiotic cell cycle
(GO:0008315)
Identical protein binding
(GO:0042802)
Kinetochore
(GO:0000776)
Kinetochore adaptor activity
(GO:0140483)
Kinetochore organization
(GO:0051383)
Metaphase chromosome alignment
(GO:0051310)
Microtubule binding
(GO:0008017)
Mitotic cell cycle checkpoint signaling
(GO:0007093)
Mitotic sister chromatid segregation
(GO:0000070)
Mitotic spindle assembly checkpoint signaling
(GO:0007094)
Mitotic spindle organization
(GO:0007052)
Ndc80 complex
(GO:0031262)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Outer kinetochore
(GO:0000940)
Positive regulation of mitotic cell cycle spindle assembly checkpoint
(GO:0090267)
Protein binding
(GO:0005515)
Regulation of protein stability
(GO:0031647)
Skeletal muscle satellite cell proliferation
(GO:0014841)
Spindle assembly involved in female meiosis i
(GO:0007057)

Other Information

Proteins

Kinetochore protein NDC80 homolog

Genular Protein ID: 3806374709

Symbol: NDC80_MOUSE

Name: Kinetochore protein NDC80 homolog

UniProtKB Accession Codes:

Q9D0F1 Q3TQT6 Q3UWM5 Q99P70

Database IDs:

Citations:

PubMed ID: 11266451

Title: The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation.

PubMed ID: 11266451

DOI: 10.1083/jcb.152.2.349

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9315664

Title: HEC, a novel nuclear protein rich in leucine heptad repeats specifically involved in mitosis.

PubMed ID: 9315664

DOI: 10.1128/mcb.17.10.6049

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 642
Mass: 73962
Checksum: 2BFF61F09B6E2CF8
Sequence:

MKRSSVSTCG AGRLSMQELR TLDLNKPGLY TPQTKERSTF GKLSTHKPTS ERKVSIFGKR 
TSGHGSRNSQ LGIFSSSEKI KDPRPLNDKA FIQQCIRQLY EFLTENGYVY SVSMKSLQAP 
STKEFLKIFA FLYGFLCPSY ELPGTKCEEE VPRIFKALGY PFTLSKSSMY TVGAPHTWPH 
IVAALVWLID CIKIDTAMKE SSPLFDDGQL WGEETEDGIK HNKLFLEYTK KCYEKFMTGA 
DSFEEEDAEL QAKLKDLYKV DASKLESLEA ENKALNEQIA RLEEEREREP NRLMSLKKLK 
ASLQADVQNY KAYMSNLESH LAVLKQKSNS LDEEIGRVEQ ECETVKQENT RLQSIVDNQK 
YSVADIERIN HEKNELQQTI NKLTKDLEAE QQQMWNEELK YARGKEAIEA QLAEYHKLAR 
KLKLIPKGAE NSKGYDFEIK FNPEAGANCL VKYRTQVYAP LKELLNESEE EINKALNKKR 
HLEDTLEQLN TMKTESKNTV RMLKEEIQKL DDLHQQAVKE AEEKDKKSAS ELESLEKHKH 
LLESGVNDGL SEAMDELDAV QREYQLTVKT TTEERRKVEN NLQRLLEMVA THVGSLEKHL 
EEENAKADRE YEEFMSEDLL ENIREMAEKY KRNAAQLKAP DK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Ndc80

Associated with

Other Information

The Ndc80p complex from Saccharomyces cerevisiae contains conserved centromere components and has a function in chromosome segregation. PubMed ID: 11266451

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334