Details for: Nrarp

Gene ID: 67122

Symbol: Nrarp

Ensembl ID: ENSMUSG00000078202

Description: Notch-regulated ankyrin repeat protein

Associated with

  • Blood vessel endothelial cell proliferation involved in sprouting angiogenesis
    (GO:0002043)
  • Branching involved in blood vessel morphogenesis
    (GO:0001569)
  • Cellular_component
    (GO:0005575)
  • Endothelial cell proliferation
    (GO:0001935)
  • Multicellular organism development
    (GO:0007275)
  • Negative regulation of notch signaling pathway
    (GO:0045746)
  • Negative regulation of t cell differentiation
    (GO:0045581)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Notch signaling pathway
    (GO:0007219)
  • Positive regulation of canonical wnt signaling pathway
    (GO:0090263)
  • Positive regulation of endothelial cell proliferation
    (GO:0001938)
  • Positive regulation of vascular endothelial cell proliferation
    (GO:1905564)
  • Regulation of cell-cell adhesion
    (GO:0022407)
  • Somite rostral/caudal axis specification
    (GO:0032525)
  • Sprouting angiogenesis
    (GO:0002040)
  • T cell differentiation
    (GO:0030217)
  • Vascular endothelial cell proliferation
    (GO:0101023)

Other Information

Genular Protein ID: 3487947830

Symbol: NRARP_MOUSE

Name: Notch-regulated ankyrin repeat-containing protein

UniProtKB Accession Codes:

Q91ZA8 Q80UV7 Q9CZM1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 5 Ensembl 1 GO 15 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 11783997

Title: The Nrarp gene encodes an ankyrin-repeat protein that is transcriptionally regulated by the notch signaling pathway.

PubMed ID: 11783997

DOI: 10.1006/dbio.2001.0408

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19268448

Title: Cyclical expression of the Notch/Wnt regulator Nrarp requires modulation by Dll3 in somitogenesis.

PubMed ID: 19268448

DOI: 10.1016/j.ydbio.2009.02.023

PubMed ID: 19154719

Title: Nrarp coordinates endothelial Notch and Wnt signaling to control vessel density in angiogenesis.

PubMed ID: 19154719

DOI: 10.1016/j.devcel.2008.12.009

PubMed ID: 21795391

Title: The period of the somite segmentation clock is sensitive to Notch activity.

PubMed ID: 21795391

DOI: 10.1091/mbc.e11-02-0139

PubMed ID: 21998026

Title: The Notch-regulated ankyrin repeat protein is required for proper anterior-posterior somite patterning in mice.

PubMed ID: 21998026

DOI: 10.1002/dvg.20813

PubMed ID: 24015274

Title: Dynamics of Notch pathway expression during mouse testis post-natal development and along the spermatogenic cycle.

PubMed ID: 24015274

DOI: 10.1371/journal.pone.0072767

Sequence Information:

  • Length: 114
  • Mass: 12492
  • Checksum: C8B84B648DB47F4F
  • Sequence:
    • MSQAELSTCS APQTQRIFQE AVRKGNTQEL QSLLQNMTNC EFNVNSFGPE GQTALHQSVI 
DGNLELVKLL VKFGADIRLA NRDGWSALHI AAFGGHQDIV LYLITKAKYA ASGR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.