Fbxo5 | ENSMUSG00000019773 | NCBI 67141

Details for: Fbxo5

Gene ID: 67141

Symbol: Fbxo5

Ensembl ID: ENSMUSG00000019773

Description: F-box protein 5

Associated with

Apc/c-mediated degradation of cell cycle proteins
(R-MMU-174143)
Cell cycle, mitotic
(R-MMU-69278)
Mitotic metaphase/anaphase transition
(R-MMU-68881)
Mitotic metaphase and anaphase
(R-MMU-2555396)
M phase
(R-MMU-68886)
Phosphorylation of emi1
(R-MMU-176417)
Regulation of apc/c activators between g1/s and early anaphase
(R-MMU-176408)
Scf-beta-trcp mediated degradation of emi1
(R-MMU-174113)
Anaphase-promoting complex binding
(GO:0010997)
Cell cycle
(GO:0007049)
Cell division
(GO:0051301)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Dna damage response
(GO:0006974)
Meiotic spindle
(GO:0072687)
Metal ion binding
(GO:0046872)
Microtubule polymerization
(GO:0046785)
Molecular function inhibitor activity
(GO:0140678)
Negative regulation of cellular senescence
(GO:2000773)
Negative regulation of dna endoreduplication
(GO:0032876)
Negative regulation of meiotic nuclear division
(GO:0045835)
Negative regulation of mitotic metaphase/anaphase transition
(GO:0045841)
Negative regulation of ubiquitin-protein transferase activity
(GO:0051444)
Negative regulation of ubiquitin protein ligase activity
(GO:1904667)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Oocyte maturation
(GO:0001556)
Positive regulation of biomineral tissue development
(GO:0070169)
Positive regulation of cell population proliferation
(GO:0008284)
Positive regulation of g2/m transition of mitotic cell cycle
(GO:0010971)
Positive regulation of meiosis i
(GO:0060903)
Positive regulation of mesenchymal stem cell migration
(GO:1905322)
Positive regulation of osteoblast differentiation
(GO:0045669)
Protein binding
(GO:0005515)
Protein kinase binding
(GO:0019901)
Regulation of dna replication
(GO:0006275)
Regulation of meiotic nuclear division
(GO:0040020)
Regulation of mitotic cell cycle
(GO:0007346)
Regulation of mitotic nuclear division
(GO:0007088)
Spindle
(GO:0005819)
Spindle assembly
(GO:0051225)
Spindle assembly involved in female meiosis i
(GO:0007057)
Ubiquitin ligase inhibitor activity
(GO:1990948)
Vesicle organization
(GO:0016050)

Other Information

Proteins

FBX5_MOUSE

Genular Protein ID: 387053194

Symbol: FBX5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q7TSG3

Database IDs:

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15526037

Title: Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes.

PubMed ID: 15526037

DOI: 10.1038/sj.emboj.7600448

PubMed ID: 16809773

Title: Mouse emi1 has an essential function in mitotic progression during early embryogenesis.

PubMed ID: 16809773

DOI: 10.1128/mcb.00043-06

PubMed ID: 17190794

Title: Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1).

PubMed ID: 17190794

DOI: 10.1083/jcb.200607070

PubMed ID: 17875940

Title: Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence.

PubMed ID: 17875940

DOI: 10.1128/mcb.00908-07

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 421
Mass: 47508
Checksum: A3624DA41F8DA285
Sequence:

MSRRTCSDLR RPSSCPCRLG ARTTVDGCKE ESPVLSVTMK CFNCNPDLSE LEVVKPEDSG 
IEASYSPVCL EPSCNDCVRN HERLSFIDSP IVGHDNKENQ RVQNTLDSSN ETEELEASRL 
YEDSGYSSFT QSDRDDGILI LENFRNSPQA RLLPSQSPDQ HPNKTLLPVL HFERVVCSTL 
KKNGKRNPKV DREMLKEVIA SGNFRLQNII GKKMGLEHLD ILAELSRRGF VHLLANILTK 
LSGMDLVNLS KVSRIWKKIL ENNKGAFQLY SKTMQRVIES SKLSLHATTR GYVVGRAALT 
CVQKSSTWAP PKKDVQIKSS SQRGQRVSTY SRHNEFVEVA KTLKNNESLK ACVRCNFPAK 
YDHYLERAVC KRESCQFEYC TKCLCAYHNN KDCLNGKILK ASCKVGPLPG TKKSKKNLQR 
L

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Fbxo5

Associated with

Other Information

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Functional interaction between p90Rsk2 and Emi1 contributes to the metaphase arrest of mouse oocytes. PubMed ID: 15526037

Mouse emi1 has an essential function in mitotic progression during early embryogenesis. PubMed ID: 16809773

Prophase I arrest and progression to metaphase I in mouse oocytes are controlled by Emi1-dependent regulation of APC(Cdh1). PubMed ID: 17190794

Loss of Emi1-dependent anaphase-promoting complex/cyclosome inhibition deregulates E2F target expression and elicits DNA damage-induced senescence. PubMed ID: 17875940