Nde1 | ENSMUSG00000022678 | NCBI 67203

Details for: Nde1

Gene ID: 67203

Symbol: Nde1

Ensembl ID: ENSMUSG00000022678

Description: nudE neurodevelopment protein 1

Associated with

Amplification of signal from the kinetochores
(R-MMU-141424)
Amplification of signal from unattached kinetochores via a mad2 inhibitory signal
(R-MMU-141444)
Anchoring of the basal body to the plasma membrane
(R-MMU-5620912)
Aurka activation by tpx2
(R-MMU-8854518)
Cell cycle, mitotic
(R-MMU-69278)
Cell cycle checkpoints
(R-MMU-69620)
Centrosome maturation
(R-MMU-380287)
Cilium assembly
(R-MMU-5617833)
Eml4 and nudc in mitotic spindle formation
(R-MMU-9648025)
G2/m transition
(R-MMU-69275)
Loss of nlp from mitotic centrosomes
(R-MMU-380259)
Loss of proteins required for interphase microtubule organization from the centrosome
(R-MMU-380284)
Mitotic anaphase
(R-MMU-68882)
Mitotic g2-g2/m phases
(R-MMU-453274)
Mitotic metaphase and anaphase
(R-MMU-2555396)
Mitotic prometaphase
(R-MMU-68877)
Mitotic spindle checkpoint
(R-MMU-69618)
M phase
(R-MMU-68886)
Organelle biogenesis and maintenance
(R-MMU-1852241)
Recruitment of mitotic centrosome proteins and complexes
(R-MMU-380270)
Recruitment of numa to mitotic centrosomes
(R-MMU-380320)
Regulation of plk1 activity at g2/m transition
(R-MMU-2565942)
Resolution of sister chromatid cohesion
(R-MMU-2500257)
Rho gtpase effectors
(R-MMU-195258)
Rho gtpases activate formins
(R-MMU-5663220)
Separation of sister chromatids
(R-MMU-2467813)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Cell cycle
(GO:0007049)
Cell differentiation
(GO:0030154)
Cell division
(GO:0051301)
Cell migration
(GO:0016477)
Centrosome
(GO:0005813)
Centrosome duplication
(GO:0051298)
Centrosome localization
(GO:0051642)
Cerebral cortex development
(GO:0021987)
Chromosome
(GO:0005694)
Chromosome, centromeric region
(GO:0000775)
Chromosome segregation
(GO:0007059)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Establishment of chromosome localization
(GO:0051303)
Establishment of mitotic spindle orientation
(GO:0000132)
Forebrain development
(GO:0030900)
Identical protein binding
(GO:0042802)
Kinesin complex
(GO:0005871)
Kinetochore
(GO:0000776)
Microtubule
(GO:0005874)
Microtubule binding
(GO:0008017)
Microtubule nucleation
(GO:0007020)
Microtubule organizing center
(GO:0005815)
Microtubule organizing center organization
(GO:0031023)
Mitotic centrosome separation
(GO:0007100)
Multicellular organism development
(GO:0007275)
Nervous system development
(GO:0007399)
Neuroblast proliferation
(GO:0007405)
Neuron migration
(GO:0001764)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Spindle
(GO:0005819)
Spindle pole centrosome
(GO:0031616)
Synapse
(GO:0045202)
Vesicle transport along microtubule
(GO:0047496)

Other Information

Proteins

Nuclear distribution protein nudE homolog 1

Genular Protein ID: 2254955871

Symbol: NDE1_MOUSE

Name: Nuclear distribution protein nudE homolog 1

UniProtKB Accession Codes:

Q9CZA6 Q3UBS6 Q3UIC1 Q9ERR0

Database IDs:

Citations:

PubMed ID: 11163258

Title: LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome.

PubMed ID: 11163258

DOI: 10.1016/s0896-6273(00)00145-8

PubMed ID: 11163259

Title: A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system.

PubMed ID: 11163259

DOI: 10.1016/s0896-6273(00)00146-x

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15473967

Title: Mitotic spindle regulation by Nde1 controls cerebral cortical size.

PubMed ID: 15473967

DOI: 10.1016/j.neuron.2004.09.023

PubMed ID: 15939891

Title: Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway.

PubMed ID: 15939891

DOI: 10.1073/pnas.0502303102

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21529751

Title: Human mutations in NDE1 cause extreme microcephaly with lissencephaly.

PubMed ID: 21529751

DOI: 10.1016/j.ajhg.2011.04.003

Sequence Information:

Length: 344
Mass: 38523
Checksum: C0A339C4F51EF8D9
Sequence:

MEDSGKTFES EEEETNYWRD LAMTYKQRAE NTQEELREFQ EGSREYEAEL EAQLQQIETR 
NRDLLSENNR LRMELESVKE KFEMQHSEGY RQISALEDDL AQTKAIKDQL QKYIRELEQA 
NDDLERAKRA TIMSLEDFEQ RLNQAIERNA FLESELDEKE NLLESVQRLK DEARDLRQEL 
AVQQKQDKPR TPMPGSGQAK RTDMAVQATG SVPSTPVAHR GPSSGLNTPG MFRRGLDSST 
SGTPLTPAAR ISALNIVGDL LRKVGALESK LASCRNFMYD QSPSRTSGPA SGRGTKNRDG 
VDRRPGSTSV GDKGSGKRLE FGKPASEPAS PALPSAQGVV KLLL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Nde1

Associated with

Other Information

LIS1 regulates CNS lamination by interacting with mNudE, a central component of the centrosome. PubMed ID: 11163258

A LIS1/NUDEL/cytoplasmic dynein heavy chain complex in the developing and adult nervous system. PubMed ID: 11163259

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Mitotic spindle regulation by Nde1 controls cerebral cortical size. PubMed ID: 15473967

Cytoplasmic LEK1 is a regulator of microtubule function through its interaction with the LIS1 pathway. PubMed ID: 15939891

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Human mutations in NDE1 cause extreme microcephaly with lissencephaly. PubMed ID: 21529751