Details for: Inava

Gene ID: 67313

Symbol: Inava

Ensembl ID: ENSMUSG00000041605

Description: innate immunity activator

Associated with

  • Adherens junction maintenance
    (GO:0034334)
  • Cytoplasm
    (GO:0005737)
  • Immune system process
    (GO:0002376)
  • Innate immune response
    (GO:0045087)
  • Intestinal epithelial structure maintenance
    (GO:0060729)
  • Molecular_function
    (GO:0003674)
  • Nuclear body
    (GO:0016604)
  • Nucleoplasm
    (GO:0005654)
  • Nucleotide-binding oligomerization domain containing 2 signaling pathway
    (GO:0070431)
  • Nucleus
    (GO:0005634)
  • Pattern recognition receptor signaling pathway
    (GO:0002221)
  • Positive regulation of canonical nf-kappab signal transduction
    (GO:0043123)
  • Positive regulation of cytokine production involved in immune response
    (GO:0002720)
  • Positive regulation of interleukin-1 beta production
    (GO:0032731)
  • Positive regulation of interleukin-6 production
    (GO:0032755)
  • Positive regulation of interleukin-10 production
    (GO:0032733)
  • Positive regulation of mapk cascade
    (GO:0043410)
  • Positive regulation of protein ubiquitination
    (GO:0031398)
  • Positive regulation of stress-activated mapk cascade
    (GO:0032874)
  • Reactive oxygen species biosynthetic process
    (GO:1903409)
  • Response to muramyl dipeptide
    (GO:0032495)
  • Response to peptidoglycan
    (GO:0032494)

Other Information

Genular Protein ID: 2944204840

Symbol: INAVA_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q7TN12 Q7TN27 Q8BGK3

Database IDs:

AGR 1 AlphaFoldDB 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 4 Ensembl 1 GO 20 GeneTree 1 InParanoid 1 InterPro 2 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMR 1 STRING 1 UniProtKB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 29420262

Title: C1orf106 is a colitis risk gene that regulates stability of epithelial adherens junctions.

PubMed ID: 29420262

DOI: 10.1126/science.aan0814

Sequence Information:

  • Length: 663
  • Mass: 72693
  • Checksum: 3B1BEB1A8D6298E1
  • Sequence:
    • MLQMPKLNEI PPGRGGPGEP WGEGRWAGPT GPEAARPARG ARGQARGARA RWDSWEHSRL 
PTHPGPGWDQ CSPSFLCAPS SQKLIMESKD EVSDSDSGII LQSGPDSPVS PMKELTNAVR 
KQQRALEARL EACLEELRRL CLREAELTGT LPAEYPLKPG EKAPKVRRRI GAAYKLDEWA 
LHREDPLSSL ERQLALQLQI TEAARRLCAE ENLSRQARRQ RKHAALQEEK KLRDLQRCLG 
DRRRNSEPPP TTVPSLGREL SASDDSSLSD GLLLEEEDSQ APKPPPESPA PPSRPLPPQS 
LEGLQPTGPE SGGQERAPIQ NSPWKETSLD HPYEKPRKSS ELSSESSSPA TTPQDQPNPS 
SLWVLDAASY HVVPIRNVPG QRQGRTSAPA TPEMQGRRGQ SQSLRVDSFR AGAEGRGRSA 
FPRRRPTHYT VTVPDSCFTP GKPPLPHPAC HSCSEDSGSD VSSISHPTSP GSSSPDISFL 
RPLCLPEPPR HRGAWGPACG RELAPHYSKL LLPAGYFPTG RYVMVAEGHL PPGEWELCRA 
AVGAAYDEEG APLRYQRLVP SHSRIVRTPS LKDSPAGRGL SKAAVSEELK WWHERARLRS 
SRPHSLDRQG AFRVRSLPPG RESFGRASGP RTQVPPVYVL RRSTDGAPVQ VFVPENGEII 
SQV

Genular Protein ID: 3379939754

Symbol: G3X9Z8_MOUSE

Name: N/A

UniProtKB Accession Codes:

G3X9Z8

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 Ensembl 2 ExpressionAtlas 1 GO 15 HOGENOM 1 InterPro 2 KEGG 1 MGI 2 MaxQB 2 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 Pfam 2 PhylomeDB 1 Proteomes 2 ProteomicsDB 2 RefSeq 1 SAM 1 SMR 1 TreeFam 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

Sequence Information:

  • Length: 677
  • Mass: 74097
  • Checksum: 2DD740FC9C49E3EA
  • Sequence:
    • MPQGTDVLGS LTFGMLQMPK LNEIPPGRGG PGEPWGEGRW AGPTGPEAAR PARGARGQAR 
GARARWDSWE HSRLPTHPGP GWDQCSPSFL CAPSSQKLIM ESKDEVSDSD SGIILQSGPD 
SPVSPMKELT NAVRKQQRAL EARLEACLEE LRRLCLREAE LTGTLPAEYP LKPGEKAPKV 
RRRIGAAYKL DEWALHREDP LSSLERQLAL QLQITEAARR LCAEENLSRQ ARRQRKHAAL 
QEEKKLRDLQ RCLGDRRRNS EPPPTTVPSL GRELSASDDS SLSDGLLLEE EDSQAPKPPP 
ESPAPPSRPL PPQSLEGLQP TGPESGGQER APIQNSPWKE TSLDHPYEKP RKSSELSSES 
SSPATTPQDQ PNPSSLWVLD AASYHVVPIR NVPGQRQGRT SAPATPEMQG RRGQSQSLRV 
DSFRAGAEGR GRSAFPRRRP THYTVTVPDS CFTPGKPPLP HPACHSCSED SGSDVSSISH 
PTSPGSSSPD ISFLRPLCLP EPPRHRGAWG PACGRELAPH YSKLLLPAGY FPTGRYVMVA 
EGHLPPGEWE LCRAAVGAAY DEEGAPLRYQ RLVPSHSRIV RTPSLKDSPA GRGLSKAAVS 
EELKWWHERA RLRSSRPHSL DRQGAFRVRS LPPGRESFGR ASGPRTQVPP VYVLRRSTDG 
APVQVFVPEN GEIISQV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.