Details for: Jam2

Gene ID: 67374

Symbol: Jam2

Ensembl ID: ENSMUSG00000053062

Description: junction adhesion molecule 2

Associated with

Other Information

Genular Protein ID: 2159270927

Symbol: JAM2_MOUSE

Name: Junctional adhesion molecule B

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 10779521

Title: Vascular endothelial junction-associated molecule, a novel member of the immunoglobulin superfamily, is localized to intercellular boundaries of endothelial cells.

PubMed ID: 10779521

DOI: 10.1074/jbc.m003189200

PubMed ID: 11036763

Title: Cloning of JAM-2 and JAM-3: an emerging junctional adhesion molecular family?

PubMed ID: 11036763

DOI: 10.1007/978-3-642-57276-0_12

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12810109

Title: Leukocyte-endothelial-cell interactions in leukocyte transmigration and the inflammatory response.

PubMed ID: 12810109

DOI: 10.1016/s1471-4906(03)00117-0

PubMed ID: 15372036

Title: Spermatid differentiation requires the assembly of a cell polarity complex downstream of junctional adhesion molecule-C.

PubMed ID: 15372036

DOI: 10.1038/nature02877

PubMed ID: 16297198

Title: Junctional adhesion molecules (JAM)-B and -C contribute to leukocyte extravasation to the skin and mediate cutaneous inflammation.

PubMed ID: 16297198

DOI: 10.1111/j.0022-202x.2005.23912.x

PubMed ID: 16093349

Title: Dual interaction of JAM-C with JAM-B and alpha(M)beta2 integrin: function in junctional complexes and leukocyte adhesion.

PubMed ID: 16093349

DOI: 10.1091/mbc.e05-04-0310

PubMed ID: 19740376

Title: Junctional adhesion molecule (JAM)-B supports lymphocyte rolling and adhesion through interaction with alpha4beta1 integrin.

PubMed ID: 19740376

DOI: 10.1111/j.1365-2567.2009.03100.x

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21868569

Title: JAM-B regulates maintenance of hematopoietic stem cells in the bone marrow.

PubMed ID: 21868569

DOI: 10.1182/blood-2010-12-323972

PubMed ID: 24357068

Title: Function of Jam-B/Jam-C interaction in homing and mobilization of human and mouse hematopoietic stem and progenitor cells.

PubMed ID: 24357068

DOI: 10.1002/stem.1624

PubMed ID: 25817991

Title: Transforming growth factor-beta3 regulates cell junction restructuring via MAPK-mediated mRNA destabilization and Smad-dependent protein degradation of junctional adhesion molecule B (JAM-B).

PubMed ID: 25817991

DOI: 10.1016/j.bbagrm.2015.03.005

PubMed ID: 25911611

Title: Junctional adhesion molecule B interferes with angiogenic VEGF/VEGFR2 signaling.

PubMed ID: 25911611

DOI: 10.1096/fj.15-270223

PubMed ID: 27499083

Title: Somatodendritic Expression of JAM2 Inhibits Oligodendrocyte Myelination.

PubMed ID: 27499083

DOI: 10.1016/j.neuron.2016.07.021

PubMed ID: 32142645

Title: Bi-allelic JAM2 Variants Lead to Early-Onset Recessive Primary Familial Brain Calcification.

PubMed ID: 32142645

DOI: 10.1016/j.ajhg.2020.02.007

Sequence Information:

  • Length: 298
  • Mass: 33047
  • Checksum: 1124E0F07E6CF751
  • Sequence:
  • MARSPQGLLM LLLLHYLIVA LDYHKANGFS ASKDHRQEVT VIEFQEAILA CKTPKKTTSS 
    RLEWKKVGQG VSLVYYQQAL QGDFKDRAEM IDFNIRIKNV TRSDAGEYRC EVSAPTEQGQ 
    NLQEDKVMLE VLVAPAVPAC EVPTSVMTGS VVELRCQDKE GNPAPEYIWF KDGTSLLGNP 
    KGGTHNNSSY TMNTKSGILQ FNMISKMDSG EYYCEARNSV GHRRCPGKRM QVDVLNISGI 
    IATVVVVAFV ISVCGLGTCY AQRKGYFSKE TSFQKGSPAS KVTTMSENDF KHTKSFII

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.