Details for: Retsat

Gene ID: 67442

Symbol: Retsat

Ensembl ID: ENSMUSG00000056666

Description: retinol saturase (all trans retinol 13,14 reductase)

Associated with

Other Information

Genular Protein ID: 3585432719

Symbol: RETST_MOUSE

Name: All-trans-retinol 13,14-reductase

UniProtKB Accession Codes:

Q64FW2 Q149J8 Q3UNN9 Q78JX8 Q8VHE7 Q9CW85

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 BRENDA 1 Bgee 1 BioCyc 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CTD 1 ChEBI 7 ChiTaRS 1 DNASU 1 EC 1 EMBL 12 Ensembl 1 ExpressionAtlas 1 GO 5 Gene3D 1 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 1 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 RefSeq 1 Rhea 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 11753649

Title: Altered gene expression profile in chemically induced rat mammary adenocarcinomas and its modulation by an aromatase inhibitor.

PubMed ID: 11753649

DOI: 10.1038/sj.onc.1204941

PubMed ID: 15358783

Title: Identification of all-trans-retinol: all-trans-13,14-dihydroretinol saturase.

PubMed ID: 15358783

DOI: 10.1074/jbc.m409130200

PubMed ID: 18289917

Title: Identification and characterization of a novel mouse peroxisome proliferator-activated receptor alpha-regulated and starvation-induced gene, Ppsig.

PubMed ID: 18289917

DOI: 10.1016/j.biocel.2008.01.006

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17253779

Title: Specificity of zebrafish retinol saturase: formation of all-trans-13,14-dihydroretinol and all-trans-7,8-dihydroretinol.

PubMed ID: 17253779

DOI: 10.1021/bi062147u

PubMed ID: 19139408

Title: Retinol saturase promotes adipogenesis and is downregulated in obesity.

PubMed ID: 19139408

DOI: 10.1073/pnas.0812065106

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 19940255

Title: Increased adiposity in the retinol saturase-knockout mouse.

PubMed ID: 19940255

DOI: 10.1096/fj.09-147207

PubMed ID: 28855500

Title: Retinol saturase coordinates liver metabolism by regulating ChREBP activity.

PubMed ID: 28855500

DOI: 10.1038/s41467-017-00430-w

Sequence Information:

  • Length: 609
  • Mass: 67334
  • Checksum: 7BC21825B8A4ABD2
  • Sequence:
    • MWITALLLAV LLLVILHRVY VGLYAASSPN PFAEDVKRPP EPLVTDKEAR KKVLKQAFSV 
SRVPEKLDAV VIGSGIGGLA SAAVLAKAGK RVLVLEQHTK AGGCCHTFGE NGLEFDTGIH 
YIGRMREGNI GRFILDQITE GQLDWAPMAS PFDLMILEGP NGRKEFPMYS GRKEYIQGLK 
KKFPKEEAVI DKYMELVKVV ARGVSHAVLL KFLPLPLTQL LSKFGLLTRF SPFCRASTQS 
LAEVLQQLGA SRELQAVLSY IFPTYGVTPS HTAFSLHALL VDHYIQGAYY PRGGSSEIAF 
HTIPLIQRAG GAVLTRATVQ SVLLDSAGRA CGVSVKKGQE LVNIYCPVVI SNAGMFNTYQ 
HLLPETVRHL PDVKKQLAMV RPGLSMLSIF ICLKGTKEDL KLQSTNYYVY FDTDMDKAME 
RYVSMPKEKA PEHIPLLFIA FPSSKDPTWE ERFPDRSTMT ALVPMAFEWF EEWQEEPKGK 
RGVDYETLKN AFVEASMSVI MKLFPQLEGK VESVTGGSPL TNQYYLAAPR GATYGADHDL 
ARLHPHAMAS IRAQTPIPNL YLTGQDIFTC GLMGALQGAL LCSSAILKRN LYSDLQALGS 
KVKAQKKKM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.