Pkp2 | ENSMUSG00000041957 | NCBI 67451

Details for: Pkp2

Gene ID: 67451

Symbol: Pkp2

Ensembl ID: ENSMUSG00000041957

Description: plakophilin 2

Associated with

Developmental biology
(R-MMU-1266738)
Formation of the cornified envelope
(R-MMU-6809371)
Keratinization
(R-MMU-6805567)
Adherens junction
(GO:0005912)
Adherens junction maintenance
(GO:0034334)
Alpha-catenin binding
(GO:0045294)
Anchoring junction
(GO:0070161)
Bundle of his cell-purkinje myocyte adhesion involved in cell communication
(GO:0086073)
Cadherin binding
(GO:0045296)
Cardiac muscle cell action potential
(GO:0086001)
Cardiac muscle cell action potential involved in contraction
(GO:0086002)
Cell-cell adhesion
(GO:0098609)
Cell-cell junction
(GO:0005911)
Cell-cell signaling involved in cardiac conduction
(GO:0086019)
Cell adhesion
(GO:0007155)
Cell junction
(GO:0030054)
Cytoplasm
(GO:0005737)
Desmosome
(GO:0030057)
Desmosome assembly
(GO:0002159)
Desmosome organization
(GO:0002934)
Gap junction assembly
(GO:0016264)
Heart development
(GO:0007507)
Intercalated disc
(GO:0014704)
Intermediate filament
(GO:0005882)
Intermediate filament binding
(GO:0019215)
Intermediate filament bundle assembly
(GO:0045110)
Lipid homeostasis
(GO:0055088)
Maintenance of animal organ identity
(GO:0048496)
Molecular adaptor activity
(GO:0060090)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of cell population proliferation
(GO:0008285)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Protein kinase c binding
(GO:0005080)
Protein localization to plasma membrane
(GO:0072659)
Regulation of bicellular tight junction assembly
(GO:2000810)
Regulation of cell-substrate adhesion
(GO:0010810)
Regulation of heart rate by cardiac conduction
(GO:0086091)
Regulation of substrate adhesion-dependent cell spreading
(GO:1900024)
Regulation of ventricular cardiac muscle cell action potential
(GO:0098911)
Ventricular cardiac muscle cell action potential
(GO:0086005)
Ventricular cardiac muscle tissue morphogenesis
(GO:0055010)

Other Information

Proteins

PKP2_MOUSE

Genular Protein ID: 292746312

Symbol: PKP2_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9CQ73 Q3TIY5

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15479741

Title: Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation.

PubMed ID: 15479741

DOI: 10.1083/jcb.200402096

PubMed ID: 17535849

Title: A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs.

PubMed ID: 17535849

DOI: 10.1242/jcs.004713

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 18630941

Title: Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis.

PubMed ID: 18630941

DOI: 10.1021/pr800223m

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 795
Mass: 88104
Checksum: BBA0B87301C4C822
Sequence:

MAVPGSLAEC GYIRTVLGQQ ILGHLDSSSL ALPSEARLRL AGSSGRGDPA ARSQRIQEQV 
QQTLARRGRS SAVSGNLHRT SSVPEYVYKL HVVENDFVGR QSPVTRDYDM LKAGMTATYG 
SRWGRAAAQY SSQKSVEERS WRQPLRRLEI SPDSSPERAH YGHSEYQYAW RSHVVPGGRL 
TLPRYARSEI LGLRQAGTAR RPPGCGSFSD AVFDNGPLKP TMPTHPPGTS HSAGSLLEET 
TVRVSQARLQ STQSRTARSS WPRSSVRSSL REPGRMLTTA GQAAVGSGDA HGDRSVFADA 
QLGNADIEMT LERAVNMLDA DHVPVSKISA AATFIQHESF QKSEARKRVN QLRGIPKLLQ 
LLKLQNEDVQ RAACGALRNL VFEDNDNKLE VAELNGVPRL LQVLKQTRDL ETKKQITGLL 
WNLSSSDKLK HLMITEALLT LTESVIIPFS GWPEGDYPKA NGLLDFDIFY NVTGCLRNMS 
SAGPDGRKMM RRCDGLIDSL VHYVRGTIAD YQPDDKATEN CVCILHNLSY QLEAELPEKY 
SQSIYMQNRN IQTNSNKSIG CFGSRSRKLK EQYQDLQMPE ERSNPHGIEW LWHSIVIRMY 
LSLIAKSTRN YTQEASLGAL QNLTAGGGPI PTLVARMVVQ KENGLQHTRK MLHVGDPSVK 
KTAVSLLRNL SRNLSLQNEI AKETLPDLVS IIPDTVPSTD LLIETTASAC YTLNNLMQNS 
YQNARDLLNT GGLQKIMTIS IGEGYAPNKA SKAASVLLYS LWAHTELHHA YKKAQFKKTD 
FVNSRTAKAY HSLKD

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Pkp2

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Requirement of plakophilin 2 for heart morphogenesis and cardiac junction formation. PubMed ID: 15479741

A unique and specific interaction between alphaT-catenin and plakophilin-2 in the area composita, the mixed-type junctional structure of cardiac intercalated discs. PubMed ID: 17535849

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

Specific phosphopeptide enrichment with immobilized titanium ion affinity chromatography adsorbent for phosphoproteome analysis. PubMed ID: 18630941

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079