Rnf41 | ENSMUSG00000025373 | NCBI 67588

Details for: Rnf41

Gene ID: 67588

Symbol: Rnf41

Ensembl ID: ENSMUSG00000025373

Description: ring finger protein 41

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-MMU-983168)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Downregulation of erbb2 signaling
(R-MMU-8863795)
Downregulation of erbb2:erbb3 signaling
(R-MMU-1358803)
Immune system
(R-MMU-168256)
Signaling by erbb2
(R-MMU-1227986)
Signaling by receptor tyrosine kinases
(R-MMU-9006934)
Signal transduction
(R-MMU-162582)
Apoptotic process
(GO:0006915)
Autophagy
(GO:0006914)
Endoplasmic reticulum tubular network
(GO:0071782)
Erythropoietin receptor binding
(GO:0005128)
Extrinsic apoptotic signaling pathway
(GO:0097191)
Identical protein binding
(GO:0042802)
Interleukin-3 receptor binding
(GO:0005135)
Metal ion binding
(GO:0046872)
Negative regulation of cell migration
(GO:0030336)
Negative regulation of cell population proliferation
(GO:0008285)
Negative regulation of mitophagy
(GO:1901525)
Perinuclear region of cytoplasm
(GO:0048471)
Positive regulation of dna-binding transcription factor activity
(GO:0051091)
Positive regulation of protein catabolic process
(GO:0045732)
Positive regulation of reactive oxygen species metabolic process
(GO:2000379)
Proteasomal protein catabolic process
(GO:0010498)
Protein autoubiquitination
(GO:0051865)
Protein binding
(GO:0005515)
Protein domain specific binding
(GO:0019904)
Protein polyubiquitination
(GO:0000209)
Protein ubiquitination
(GO:0016567)
Receptor tyrosine kinase binding
(GO:0030971)
Regulation of establishment of cell polarity
(GO:2000114)
Regulation of gene expression
(GO:0010468)
Regulation of lymphocyte differentiation
(GO:0045619)
Regulation of mapk cascade
(GO:0043408)
Regulation of myeloid cell differentiation
(GO:0045637)
Regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051896)
Regulation of reactive oxygen species metabolic process
(GO:2000377)
Small gtpase binding
(GO:0031267)
Transferase activity
(GO:0016740)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin protein ligase activity
(GO:0061630)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

E3 ubiquitin-protein ligase NRDP1

Genular Protein ID: 717811963

Symbol: RNF41_MOUSE

Name: E3 ubiquitin-protein ligase NRDP1

UniProtKB Accession Codes:

Q8BH75 Q8BGJ2 Q8BMC9 Q8VEA2 Q9CRK6 Q9D568

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18495327

Title: E3 ligase FLRF (Rnf41) regulates differentiation of hematopoietic progenitors by governing steady-state levels of cytokine and retinoic acid receptors.

PubMed ID: 18495327

DOI: 10.1016/j.exphem.2008.04.001

PubMed ID: 19483718

Title: The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon.

PubMed ID: 19483718

DOI: 10.1038/ni.1742

PubMed ID: 24949970

Title: The diabetes susceptibility gene Clec16a regulates mitophagy.

PubMed ID: 24949970

DOI: 10.1016/j.cell.2014.05.016

PubMed ID: 17384230

Title: Structure-based mutagenesis of the substrate-recognition domain of Nrdp1/FLRF identifies the binding site for the receptor tyrosine kinase ErbB3.

PubMed ID: 17384230

DOI: 10.1110/ps.062700307

Sequence Information:

Length: 317
Mass: 35891
Checksum: 43FE844C06392802
Sequence:

MGYDVTRFQG DVDEDLICPI CSGVLEEPVQ APHCEHAFCN ACITQWFSQQ QTCPVDRSVV 
TVAHLRPVPR IMRNMLSKLQ IACDNAVFGC SAVVRLDNLM SHLSDCEHNP KRPVTCEQGC 
GLEMPKDELP NHNCIKHLRS VVQQQQSRIA ELEKTSAEHK HQLAEQKRDI QLLKAYMRAI 
RSVNPNLQNL EETIEYNEIL EWVNSLQPAR VTRWGGMIST PDAVLQAVIK RSLVESGCPA 
SIVNELIENA HERSWPQGLA TLETRQMNRR YYENYVAKRI PGKQAVVVMA CENQHMGDDM 
VQEPGLVMIF AHGVEEI

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rnf41

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

E3 ligase FLRF (Rnf41) regulates differentiation of hematopoietic progenitors by governing steady-state levels of cytokine and retinoic acid receptors. PubMed ID: 18495327

The E3 ubiquitin ligase Nrdp1 'preferentially' promotes TLR-mediated production of type I interferon. PubMed ID: 19483718

The diabetes susceptibility gene Clec16a regulates mitophagy. PubMed ID: 24949970