Details for: BRDT

Gene ID: 676

Symbol: BRDT

Ensembl ID: ENSG00000137948

Description: bromodomain testis associated

Associated with

Other Information

Genular Protein ID: 1665577132

Symbol: BRDT_HUMAN

Name: Bromodomain testis-specific protein

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9367677

Title: Identification and characterization of BRDT: a testis-specific gene related to the bromodomain genes RING3 and Drosophila fsh.

PubMed ID: 9367677

DOI: 10.1006/geno.1997.5000

PubMed ID: 15647849

Title: Molecular cloning and expression of a novel alternative splice variant of BRDT gene.

PubMed ID: 15647849

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10704737

Title: Expression of cancer-testis antigens in lung cancer: definition of bromodomain testis-specific gene (BRDT) as a new CT gene, CT9.

PubMed ID: 10704737

DOI: 10.1016/s0304-3835(99)00385-7

PubMed ID: 17344846

Title: Patterns of somatic mutation in human cancer genomes.

PubMed ID: 17344846

DOI: 10.1038/nature05610

PubMed ID: 20538714

Title: The interaction of modified histones with the bromodomain testis-specific (BRDT) gene and its mRNA level in sperm of fertile donors and subfertile men.

PubMed ID: 20538714

DOI: 10.1530/rep-10-0139

PubMed ID: 22971749

Title: The conserved 12-amino acid stretch in the inter-bromodomain region of BET family proteins functions as a nuclear localization signal.

PubMed ID: 22971749

DOI: 10.1248/bpb.b12-00527

PubMed ID: 25593309

Title: Screen identifies bromodomain protein ZMYND8 in chromatin recognition of transcription-associated DNA damage that promotes homologous recombination.

PubMed ID: 25593309

DOI: 10.1101/gad.252189.114

PubMed ID: 22464331

Title: Histone recognition and large-scale structural analysis of the human bromodomain family.

PubMed ID: 22464331

DOI: 10.1016/j.cell.2012.02.013

PubMed ID: 22901802

Title: Small-molecule inhibition of BRDT for male contraception.

PubMed ID: 22901802

DOI: 10.1016/j.cell.2012.06.045

PubMed ID: 28199965

Title: Whole-exome sequencing identified a homozygous BRDT mutation in a patient with acephalic spermatozoa.

PubMed ID: 28199965

DOI: 10.18632/oncotarget.15251

Sequence Information:

  • Length: 947
  • Mass: 107954
  • Checksum: 09C0FD8690E217BB
  • Sequence:
  • MSLPSRQTAI IVNPPPPEYI NTKKNGRLTN QLQYLQKVVL KDLWKHSFSW PFQRPVDAVK 
    LQLPDYYTII KNPMDLNTIK KRLENKYYAK ASECIEDFNT MFSNCYLYNK PGDDIVLMAQ 
    ALEKLFMQKL SQMPQEEQVV GVKERIKKGT QQNIAVSSAK EKSSPSATEK VFKQQEIPSV 
    FPKTSISPLN VVQGASVNSS SQTAAQVTKG VKRKADTTTP ATSAVKASSE FSPTFTEKSV 
    ALPPIKENMP KNVLPDSQQQ YNVVKTVKVT EQLRHCSEIL KEMLAKKHFS YAWPFYNPVD 
    VNALGLHNYY DVVKNPMDLG TIKEKMDNQE YKDAYKFAAD VRLMFMNCYK YNPPDHEVVT 
    MARMLQDVFE THFSKIPIEP VESMPLCYIK TDITETTGRE NTNEASSEGN SSDDSEDERV 
    KRLAKLQEQL KAVHQQLQVL SQVPFRKLNK KKEKSKKEKK KEKVNNSNEN PRKMCEQMRL 
    KEKSKRNQPK KRKQQFIGLK SEDEDNAKPM NYDEKRQLSL NINKLPGDKL GRVVHIIQSR 
    EPSLSNSNPD EIEIDFETLK ASTLRELEKY VSACLRKRPL KPPAKKIMMS KEELHSQKKQ 
    ELEKRLLDVN NQLNSRKRQT KSDKTQPSKA VENVSRLSES SSSSSSSSES ESSSSDLSSS 
    DSSDSESEMF PKFTEVKPND SPSKENVKKM KNECIPPEGR TGVTQIGYCV QDTTSANTTL 
    VHQTTPSHVM PPNHHQLAFN YQELEHLQTV KNISPLQILP PSGDSEQLSN GITVMHPSGD 
    SDTTMLESEC QAPVQKDIKI KNADSWKSLG KPVKPSGVMK SSDELFNQFR KAAIEKEVKA 
    RTQELIRKHL EQNTKELKAS QENQRDLGNG LTVESFSNKI QNKCSGEEQK EHQQSSEAQD 
    KSKLWLLKDR DLARQKEQER RRREAMVGTI DMTLQSDIMT MFENNFD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.