Details for: Necap1

Gene ID: 67602

Symbol: Necap1

Ensembl ID: ENSMUSG00000030327

Description: NECAP endocytosis associated 1

Associated with

Other Information

Genular Protein ID: 1424227621

Symbol: NECP1_MOUSE

Name: Adaptin ear-binding coat-associated protein 1

UniProtKB Accession Codes:

Q9CR95 Q3TH13 Q78JW3 Q8C4P1

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 DIP 1 DNASU 1 EMBL 6 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 7 Gene3D 1 GeneTree 1 Genevisible 1 GlyGen 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 2 KEGG 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PDB 2 PDBsum 1 PRO 1 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 3 RefSeq 1 SAM 1 SMR 1 STRING 1 SUPFAM 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14555962

Title: Identification of a family of endocytic proteins that define a new alpha-adaptin ear-binding motif.

PubMed ID: 14555962

DOI: 10.1038/sj.embor.embor7400004

PubMed ID: 15359277

Title: Two WXXF-based motifs in NECAPs define the specificity of accessory protein binding to AP-1 and AP-2.

PubMed ID: 15359277

DOI: 10.1038/sj.emboj.7600378

PubMed ID: 14665628

Title: Definition of the consensus motif recognized by gamma-adaptin ear domains.

PubMed ID: 14665628

DOI: 10.1074/jbc.m311873200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24399846

Title: NECAP1 loss of function leads to a severe infantile epileptic encephalopathy.

PubMed ID: 24399846

DOI: 10.1136/jmedgenet-2013-102030

Sequence Information:

  • Length: 275
  • Mass: 29639
  • Checksum: B238B083746FF915
  • Sequence:
    • MAAELEYESV LCVKPDVSVY RIPPRASNRG YRASDWKLDQ PDWTGRLRIT SKGKIAYIKL 
EDKVSGELFA QAPVEQYPGI AVETVTDSSR YFVIRIQDGT GRSAFIGIGF TDRGDAFDFN 
VSLQDHFKWV KQETEISKES QEMDNRPKLD LGFKEGQTIK LSIGNITAKK GGASKPRASG 
TGGLSLLPPP PGGKVTIPPP SSSVAISNHV TPPPIPKSNH GGNDSDILLD LDSPAPVSTS 
APAPVSTSND LWGDFSTASS SVPNQAPQPS NWVQF

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.