Elob | ENSMUSG00000055839 | NCBI 67673

Details for: Elob

Gene ID: 67673

Symbol: Elob

Ensembl ID: ENSMUSG00000055839

Description: elongin B

Associated with

Adaptive immune system
(R-MMU-1280218)
Antigen processing: ubiquitination & proteasome degradation
(R-MMU-983168)
Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to hypoxia
(R-MMU-1234174)
Class i mhc mediated antigen processing & presentation
(R-MMU-983169)
Cytokine signaling in immune system
(R-MMU-1280215)
Formation of rna pol ii elongation complex
(R-MMU-112382)
Gene expression (transcription)
(R-MMU-74160)
Generic transcription pathway
(R-MMU-212436)
Immune system
(R-MMU-168256)
Inactivation of csf3 (g-csf) signaling
(R-MMU-9705462)
Metabolism of proteins
(R-MMU-392499)
Neddylation
(R-MMU-8951664)
Oxygen-dependent proline hydroxylation of hypoxia-inducible factor alpha
(R-MMU-1234176)
Post-translational protein modification
(R-MMU-597592)
Rna polymerase ii pre-transcription events
(R-MMU-674695)
Rna polymerase ii transcription
(R-MMU-73857)
Rna polymerase ii transcription elongation
(R-MMU-75955)
Signaling by csf3 (g-csf)
(R-MMU-9674555)
Tp53 regulates transcription of dna repair genes
(R-MMU-6796648)
Transcriptional regulation by tp53
(R-MMU-3700989)
Cul2-ring ubiquitin ligase complex
(GO:0031462)
Cul5-ring ubiquitin ligase complex
(GO:0031466)
Cytosol
(GO:0005829)
Elongin complex
(GO:0070449)
Nucleus
(GO:0005634)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Target-directed mirna degradation
(GO:0140958)
Transcription coactivator activity
(GO:0003713)
Transcription corepressor binding
(GO:0001222)
Transcription elongation by rna polymerase ii
(GO:0006368)
Transcription initiation at rna polymerase ii promoter
(GO:0006367)
Transcription regulator complex
(GO:0005667)
Ubiquitin protein ligase binding
(GO:0031625)
Vcb complex
(GO:0030891)

Other Information

Proteins

Elongin-B

Genular Protein ID: 2297731870

Symbol: ELOB_MOUSE

Name: Elongin-B

UniProtKB Accession Codes:

P62869 Q63529 Q80W20

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10051596

Title: The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation.

PubMed ID: 10051596

DOI: 10.1073/pnas.96.5.2071

PubMed ID: 11384984

Title: Muf1, a novel elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase.

PubMed ID: 11384984

DOI: 10.1074/jbc.m103093200

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 27863225

Title: EPOP functionally links elongin and Polycomb in pluripotent stem cells.

PubMed ID: 27863225

DOI: 10.1016/j.molcel.2016.10.018

PubMed ID: 27863226

Title: EPOP interacts with elongin BC and USP7 to modulate the chromatin landscape.

PubMed ID: 27863226

DOI: 10.1016/j.molcel.2016.10.019

PubMed ID: 28061330

Title:

PubMed ID: 28061330

DOI: 10.1016/j.molcel.2016.12.006

PubMed ID: 33590678

Title: CUL2LRR1, TRAIP and p97 control CMG helicase disassembly in the mammalian cell cycle.

PubMed ID: 33590678

DOI: 10.15252/embr.202052164

PubMed ID: 16498413

Title: Structural and functional insights into the B30.2/SPRY domain.

PubMed ID: 16498413

DOI: 10.1038/sj.emboj.7600994

Sequence Information:

Length: 118
Mass: 13170
Checksum: BA702F24CEC0FC02
Sequence:

MDVFLMIRRH KTTIFTDAKE SSTVFELKRI VEGILKRPPE EQRLYKDDQL LDDGKTLGEC 
GFTSQTARPQ APATVGLAFR ADDTFEALRI EPFSSPPELP DVMKPQDSGG SANEQAVQ

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Elob

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation. PubMed ID: 10051596

Muf1, a novel elongin BC-interacting leucine-rich repeat protein that can assemble with Cul5 and Rbx1 to reconstitute a ubiquitin ligase. PubMed ID: 11384984

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

EPOP functionally links elongin and Polycomb in pluripotent stem cells. PubMed ID: 27863225

EPOP interacts with elongin BC and USP7 to modulate the chromatin landscape. PubMed ID: 27863226