Dph2 | ENSMUSG00000028540 | NCBI 67728

Details for: Dph2

Gene ID: 67728

Symbol: Dph2

Ensembl ID: ENSMUSG00000028540

Description: DPH2 homolog

Associated with

Gamma carboxylation, hypusinylation, hydroxylation, and arylsulfatase activation
(R-MMU-163841)
Metabolism of proteins
(R-MMU-392499)
Post-translational protein modification
(R-MMU-597592)
Synthesis of diphthamide-eef2
(R-MMU-5358493)
2-(3-amino-3-carboxypropyl)histidine synthase activity
(GO:0090560)
Cellular_component
(GO:0005575)
Iron-sulfur cluster binding
(GO:0051536)
Metal ion binding
(GO:0046872)
Protein binding
(GO:0005515)
Protein histidyl modification to diphthamide
(GO:0017183)

Other Information

Proteins

Diphthamide biosynthesis protein 2

Genular Protein ID: 2116329108

Symbol: DPH2_MOUSE

Name: Diphthamide biosynthesis protein 2

UniProtKB Accession Codes:

Q9CR25 Q8K0L8

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15485916

Title: Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2.

PubMed ID: 15485916

DOI: 10.1128/mcb.24.21.9487-9497.2004

PubMed ID: 17242355

Title: Large-scale phosphorylation analysis of mouse liver.

PubMed ID: 17242355

DOI: 10.1073/pnas.0609836104

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 21203470

Title: A dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxin.

PubMed ID: 21203470

DOI: 10.1371/journal.pone.0015753

Sequence Information:

Length: 489
Mass: 52365
Checksum: 2D94A8FEDE63DD39
Sequence:

MESTFSSPAE AALQREAGVP GQFTPPEDLD RVYELERVTK FVCDLGCQRV TLQFPDQLLG 
DAGAVAARLE EVTGAKMFIL GDTAYGSCCV DVLGAEQAGA QALVHFGPAC LSPPASQLPI 
TFVLGQRPVA LELCAKAFEA QNPDPTAPVV LLSEPACAHA LEPLAMLLLP KYQDLLISRP 
ALPLPVGSPS SQPESLERFG RCFPLNPGRR LEEYGAFYVG ASQASSDSSL DPDLSRLLLG 
WTPGRPFFSC CPDTGQTQDQ GAKAGRLRAR RLYLIERARD ARVVGLLAGT LGVARHREAL 
AHLRKLTEAA GKRSYVLAVG KPTPAKLANF PEMDVFVLLA CPLGALAPQP SGGFFRPVLT 
PCELEAACNP AWPPPGLAPH LTHYAELLPG SPFHVPLPPP ESELWDTPDV SLISGELRPP 
PPWKSSDDTR CSALIPRPQL ELAESSPAAS FLSSRNWQGL EPRLGQTPVK EAVRGRRGIA 
IAYEDEGSS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Dph2

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Identification of the proteins required for biosynthesis of diphthamide, the target of bacterial ADP-ribosylating toxins on translation elongation factor 2. PubMed ID: 15485916

Large-scale phosphorylation analysis of mouse liver. PubMed ID: 17242355

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

A dominant-negative approach that prevents diphthamide formation confers resistance to Pseudomonas exotoxin A and diphtheria toxin. PubMed ID: 21203470