Details for: ZFP36L2

Gene ID: 678

Symbol: ZFP36L2

Ensembl ID: ENSG00000152518

Description: ZFP36 ring finger protein like 2

Associated with

  • Developmental biology
    (R-HSA-1266738)
  • M-decay: degradation of maternal mrnas by maternally stored factors
    (R-HSA-9820841)
  • Maternal to zygotic transition (mzt)
    (R-HSA-9816359)
  • 3'-utr-mediated mrna destabilization
    (GO:0061158)
  • Cellular response to epidermal growth factor stimulus
    (GO:0071364)
  • Cellular response to fibroblast growth factor stimulus
    (GO:0044344)
  • Cellular response to glucocorticoid stimulus
    (GO:0071385)
  • Cellular response to granulocyte macrophage colony-stimulating factor stimulus
    (GO:0097011)
  • Cellular response to transforming growth factor beta stimulus
    (GO:0071560)
  • Cellular response to tumor necrosis factor
    (GO:0071356)
  • Cytoplasm
    (GO:0005737)
  • Definitive hemopoiesis
    (GO:0060216)
  • Erk1 and erk2 cascade
    (GO:0070371)
  • Hemopoiesis
    (GO:0030097)
  • Metal ion binding
    (GO:0046872)
  • Mrna 3'-utr au-rich region binding
    (GO:0035925)
  • Mrna catabolic process
    (GO:0006402)
  • Negative regulation of fat cell differentiation
    (GO:0045599)
  • Negative regulation of mitotic cell cycle phase transition
    (GO:1901991)
  • Negative regulation of stem cell differentiation
    (GO:2000737)
  • Nuclear-transcribed mrna catabolic process, deadenylation-dependent decay
    (GO:0000288)
  • Nucleus
    (GO:0005634)
  • Positive regulation of nuclear-transcribed mrna catabolic process, deadenylation-dependent decay
    (GO:1900153)
  • Protein binding
    (GO:0005515)
  • Regulation of b cell differentiation
    (GO:0045577)
  • Regulation of mrna stability
    (GO:0043488)
  • Response to wounding
    (GO:0009611)
  • Ribonucleoprotein complex
    (GO:1990904)
  • Rna binding
    (GO:0003723)
  • Somatic stem cell division
    (GO:0048103)
  • Somatic stem cell population maintenance
    (GO:0035019)
  • T cell differentiation in thymus
    (GO:0033077)

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 653.9577
    Cell Significance Index: -101.7200
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 308.7800
    Cell Significance Index: -78.3200
  • Cell Name: embryonic stem cell (CL0002322)
    Fold Change: 297.3072
    Cell Significance Index: -122.4800
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 247.4357
    Cell Significance Index: -116.8200
  • Cell Name: peripheral blood mononuclear cell (CL2000001)
    Fold Change: 244.7387
    Cell Significance Index: -125.8900
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 174.3907
    Cell Significance Index: -117.0200
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 90.2303
    Cell Significance Index: -111.2500
  • Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
    Fold Change: 33.4955
    Cell Significance Index: -102.8800
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 29.7234
    Cell Significance Index: -117.2900
  • Cell Name: epidermal Langerhans cell (CL0002457)
    Fold Change: 28.1871
    Cell Significance Index: -61.6900
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 24.4542
    Cell Significance Index: 65.5100
  • Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
    Fold Change: 23.1852
    Cell Significance Index: -62.1100
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: 4.9262
    Cell Significance Index: 317.8200
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 4.8741
    Cell Significance Index: 132.6700
  • Cell Name: endothelial cell of venule (CL1000414)
    Fold Change: 4.8449
    Cell Significance Index: 55.0400
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: 4.6499
    Cell Significance Index: 218.5400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: 3.9252
    Cell Significance Index: 277.6100
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: 3.8884
    Cell Significance Index: 478.1200
  • Cell Name: vascular lymphangioblast (CL0005022)
    Fold Change: 3.8568
    Cell Significance Index: 68.1600
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: 3.7765
    Cell Significance Index: 1669.6700
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 3.7152
    Cell Significance Index: 106.5000
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 3.5975
    Cell Significance Index: 268.1200
  • Cell Name: stem cell of epidermis (CL1000428)
    Fold Change: 3.4902
    Cell Significance Index: 10.3800
  • Cell Name: lactocyte (CL0002325)
    Fold Change: 3.1810
    Cell Significance Index: 410.9600
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 3.1543
    Cell Significance Index: 433.1700
  • Cell Name: odontoblast (CL0000060)
    Fold Change: 2.9673
    Cell Significance Index: 380.3900
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: 2.7284
    Cell Significance Index: 50.4300
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: 2.0159
    Cell Significance Index: 363.4000
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.8153
    Cell Significance Index: 1639.0800
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: 1.4870
    Cell Significance Index: 67.4000
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 1.4807
    Cell Significance Index: 28.9000
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 1.3558
    Cell Significance Index: 35.6500
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 1.1645
    Cell Significance Index: 635.9400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.0584
    Cell Significance Index: 210.0500
  • Cell Name: peg cell (CL4033014)
    Fold Change: 0.9553
    Cell Significance Index: 22.0700
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: 0.8145
    Cell Significance Index: 12.3700
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: 0.7898
    Cell Significance Index: 22.7600
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.7795
    Cell Significance Index: 39.4000
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.7150
    Cell Significance Index: 70.7300
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: 0.6556
    Cell Significance Index: 77.3100
  • Cell Name: fibroblast of dermis (CL0002551)
    Fold Change: 0.4723
    Cell Significance Index: 9.8900
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: 0.4624
    Cell Significance Index: 21.5600
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: 0.3905
    Cell Significance Index: 21.9200
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.2865
    Cell Significance Index: 54.5200
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.2849
    Cell Significance Index: 19.7100
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0734
    Cell Significance Index: 2.0500
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0333
    Cell Significance Index: 62.7400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 0.0323
    Cell Significance Index: 5.5100
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: 0.0029
    Cell Significance Index: 2.1000
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0051
    Cell Significance Index: -0.1800
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0140
    Cell Significance Index: -1.4300
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0505
    Cell Significance Index: -93.0800
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0665
    Cell Significance Index: -49.2500
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0729
    Cell Significance Index: -112.2900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0941
    Cell Significance Index: -59.7700
  • Cell Name: pancreatic PP cell (CL0002275)
    Fold Change: -0.0955
    Cell Significance Index: -59.6600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0994
    Cell Significance Index: -75.2100
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.1004
    Cell Significance Index: -136.4600
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.1545
    Cell Significance Index: -87.1200
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: -0.1673
    Cell Significance Index: -115.7200
  • Cell Name: skeletal muscle fibroblast (CL0011027)
    Fold Change: -0.2229
    Cell Significance Index: -1.5100
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.2363
    Cell Significance Index: -107.2700
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: -0.3172
    Cell Significance Index: -51.5900
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.3237
    Cell Significance Index: -68.1900
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: -0.3271
    Cell Significance Index: -117.3100
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: -0.3295
    Cell Significance Index: -5.5200
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: -0.3427
    Cell Significance Index: -98.6100
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.3949
    Cell Significance Index: -45.2400
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.4124
    Cell Significance Index: -13.2100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.5332
    Cell Significance Index: -77.5100
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: -0.5731
    Cell Significance Index: -114.9700
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.6102
    Cell Significance Index: -71.1100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: -0.6265
    Cell Significance Index: -15.6600
  • Cell Name: pro-T cell (CL0000827)
    Fold Change: -0.6294
    Cell Significance Index: -16.0800
  • Cell Name: luminal hormone-sensing cell of mammary gland (CL4033058)
    Fold Change: -0.7312
    Cell Significance Index: -4.5000
  • Cell Name: pancreatic endocrine cell (CL0008024)
    Fold Change: -0.7644
    Cell Significance Index: -87.2600
  • Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
    Fold Change: -0.7767
    Cell Significance Index: -13.3900
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: -1.0724
    Cell Significance Index: -28.6900
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -1.1127
    Cell Significance Index: -115.8600
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -1.1662
    Cell Significance Index: -89.4900
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: -1.1888
    Cell Significance Index: -31.8600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -1.2536
    Cell Significance Index: -65.1200
  • Cell Name: mesonephric nephron tubule epithelial cell (CL1000022)
    Fold Change: -1.2547
    Cell Significance Index: -43.6000
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -1.2650
    Cell Significance Index: -100.1900
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -1.3958
    Cell Significance Index: -57.1900
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: -1.6003
    Cell Significance Index: -20.5000
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -1.6352
    Cell Significance Index: -100.2500
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: -1.6414
    Cell Significance Index: -35.5600
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -1.7972
    Cell Significance Index: -18.6100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -1.8108
    Cell Significance Index: -111.3000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -1.8178
    Cell Significance Index: -122.2300
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -1.8387
    Cell Significance Index: -115.8900
  • Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
    Fold Change: -2.0004
    Cell Significance Index: -58.7500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -2.1944
    Cell Significance Index: -29.9400
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -2.4486
    Cell Significance Index: -128.5600
  • Cell Name: umbrella cell of urothelium (CL4030056)
    Fold Change: -2.4634
    Cell Significance Index: -22.6900
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -2.6081
    Cell Significance Index: -76.8200
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: -2.6306
    Cell Significance Index: -40.7000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -2.6489
    Cell Significance Index: -97.2400
  • Cell Name: fibroblast of cardiac tissue (CL0002548)
    Fold Change: -2.6929
    Cell Significance Index: -38.6700

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** The ZFP36L2 gene is a member of the ZFP36 family of proteins, which are characterized by their ring finger protein-like domain. This gene is specifically expressed in immune cells, including T cells, natural killer cells, and dendritic cells. ZFP36L2 is localized to the cytoplasm and nucleus, where it interacts with various signaling pathways and transcription factors to regulate mRNA stability and translation. **Pathways and Functions:** ZFP36L2 is involved in multiple cellular processes, including: 1. **mRNA destabilization and translation regulation**: ZFP36L2 binds to AREs in target mRNAs, leading to their degradation or translational repression. This regulates the expression of genes involved in immune cell development, function, and homeostasis. 2. **Cellular response to growth factors**: ZFP36L2 is activated by growth factors such as epidermal growth factor (EGF) and fibroblast growth factor (FGF), leading to the regulation of immune cell proliferation and differentiation. 3. **Negative regulation of fat cell differentiation**: ZFP36L2 has been shown to inhibit the differentiation of adipocytes, highlighting its role in regulating metabolic processes. 4. **Regulation of stem cell differentiation**: ZFP36L2 has been implicated in the regulation of stem cell differentiation in various cell types, including immune cells. **Clinical Significance:** Dysregulation of ZFP36L2 has been associated with various immune-related disorders, including: 1. **Autoimmune diseases**: ZFP36L2 has been implicated in the regulation of immune cell function and homeostasis, and its dysregulation has been linked to autoimmune diseases such as rheumatoid arthritis and lupus. 2. **Cancer**: ZFP36L2 has been shown to regulate tumor cell growth and survival, and its dysregulation has been associated with cancer progression. 3. **Infectious diseases**: ZFP36L2 has been implicated in the regulation of immune cell function and response to infection, and its dysregulation has been linked to infectious diseases such as HIV and tuberculosis. In conclusion, the ZFP36L2 gene is a critical regulator of immune cell development and function, and its dysregulation has been associated with various immune-related disorders. Further research is needed to fully understand the mechanisms by which ZFP36L2 regulates immune cell function and to develop therapeutic strategies to target its dysregulation in disease.

Genular Protein ID: 2812763884

Symbol: TISD_HUMAN

Name: N/A

UniProtKB Accession Codes:

P47974 Q53TB4 Q9BSJ3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CORUM 1 CTD 1 ChiTaRS 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 5 Ensembl 1 EvolutionaryTrace 1 GO 28 Gene3D 1 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyGen 1 HGNC 1 HOGENOM 1 HPA 1 IDEAL 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 1 PDBsum 1 PIR 1 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 2 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 1 RefSeq 1 SMART 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 8545129

Title: Identification of a member of the TIS11 early response gene family at the insertion point of a DNA fragment containing a gene for the T-cell receptor beta chain in an acute T-cell leukemia.

PubMed ID: 8545129

PubMed ID: 7835719

Title: ERF-2, the human homologue of the murine Tis11d early response gene.

PubMed ID: 7835719

DOI: 10.1016/0378-1119(94)00696-p

PubMed ID: 15815621

Title: Generation and annotation of the DNA sequences of human chromosomes 2 and 4.

PubMed ID: 15815621

DOI: 10.1038/nature03466

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 10367403

Title: Differential effects of sodium butyrate on the transcription of the human TIS11 family of early-response genes in colorectal cancer cells.

PubMed ID: 10367403

PubMed ID: 18669648

Title: A quantitative atlas of mitotic phosphorylation.

PubMed ID: 18669648

DOI: 10.1073/pnas.0805139105

PubMed ID: 20166898

Title: ZFP36L1 is regulated by growth factors and cytokines in keratinocytes and influences their VEGF production.

PubMed ID: 20166898

DOI: 10.3109/08977190903578660

PubMed ID: 20506496

Title: A computational study of RNA binding and specificity in the tandem zinc finger domain of TIS11d.

PubMed ID: 20506496

DOI: 10.1002/pro.401

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21109922

Title: Mutation in the RNA binding protein TIS11D/ZFP36L2 is associated with the pathogenesis of acute leukemia.

PubMed ID: 21109922

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25106868

Title: ZFP36L1 and ZFP36L2 control LDLR mRNA stability via the ERK-RSK pathway.

PubMed ID: 25106868

DOI: 10.1093/nar/gku652

PubMed ID: 27182009

Title: Functional analysis of ZFP36 proteins in keratinocytes.

PubMed ID: 27182009

DOI: 10.1016/j.ejcb.2016.04.007

PubMed ID: 34611029

Title: Biallelic variants in ZFP36L2 cause female infertility characterised by recurrent preimplantation embryo arrest.

PubMed ID: 34611029

DOI: 10.1136/jmedgenet-2021-107933

PubMed ID: 14981510

Title: Recognition of the mRNA AU-rich element by the zinc finger domain of TIS11d.

PubMed ID: 14981510

DOI: 10.1038/nsmb738

Sequence Information:

  • Length: 494
  • Mass: 51063
  • Checksum: 10E23FA9E2DDABD4
  • Sequence:
    • MSTTLLSAFY DVDFLCKTEK SLANLNLNNM LDKKAVGTPV AAAPSSGFAP GFLRRHSASN 
LHALAHPAPS PGSCSPKFPG AANGSSCGSA AAGGPTSYGT LKEPSGGGGT ALLNKENKFR 
DRSFSENGDR SQHLLHLQQQ QKGGGGSQIN STRYKTELCR PFEESGTCKY GEKCQFAHGF 
HELRSLTRHP KYKTELCRTF HTIGFCPYGP RCHFIHNADE RRPAPSGGAS GDLRAFGTRD 
ALHLGFPREP RPKLHHSLSF SGFPSGHHQP PGGLESPLLL DSPTSRTPPP PSCSSASSCS 
SSASSCSSAS AASTPSGAPT CCASAAAAAA AALLYGTGGA EDLLAPGAPC AACSSASCAN 
NAFAFGPELS SLITPLAIQT HNFAAVAAAA YYRSQQQQQQ QGLAPPAQPP APPSATLPAG 
AAAPPSPPFS FQLPRRLSDS PVFDAPPSPP DSLSDRDSYL SGSLSSGSLS GSESPSLDPG 
RRLPIFSRLS ISDD

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.