Details for: Dgat2

Gene ID: 67800

Symbol: Dgat2

Ensembl ID: ENSMUSG00000030747

Description: diacylglycerol O-acyltransferase 2

Associated with

Other Information

Genular Protein ID: 2304292756

Symbol: DGAT2_MOUSE

Name: Acyl-CoA retinol O-fatty-acyltransferase

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11481335

Title: Cloning of DGAT2, a second mammalian diacylglycerol acyltransferase, and related family members.

PubMed ID: 11481335

DOI: 10.1074/jbc.m106219200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12413942

Title: Concerted elevation of acyl-coenzyme A:diacylglycerol acyltransferase (DGAT) activity through independent stimulation of mRNA expression of DGAT1 and DGAT2 by carbohydrate and insulin.

PubMed ID: 12413942

DOI: 10.1016/s0006-291x(02)02466-x

PubMed ID: 14521909

Title: A novel diacylglycerol acyltransferase (DGAT2) is decreased in human psoriatic skin and increased in diabetic mice.

PubMed ID: 14521909

DOI: 10.1016/j.bbrc.2003.09.015

PubMed ID: 14668353

Title: Lipopenia and skin barrier abnormalities in DGAT2-deficient mice.

PubMed ID: 14668353

DOI: 10.1074/jbc.m311000200

PubMed ID: 15258194

Title: Niacin noncompetitively inhibits DGAT2 but not DGAT1 activity in HepG2 cells.

PubMed ID: 15258194

DOI: 10.1194/jlr.m300403-jlr200

PubMed ID: 16001399

Title: Antisense oligonucleotide reduction of DGAT2 expression improves hepatic steatosis and hyperlipidemia in obese mice.

PubMed ID: 16001399

DOI: 10.1002/hep.20783

PubMed ID: 15797871

Title: Increased very low density lipoprotein secretion and gonadal fat mass in mice overexpressing liver DGAT1.

PubMed ID: 15797871

DOI: 10.1074/jbc.m412989200

PubMed ID: 15834126

Title: The triacylglycerol synthesis enzyme DGAT1 also catalyzes the synthesis of diacylglycerols, waxes, and retinyl esters.

PubMed ID: 15834126

DOI: 10.1194/jlr.m500036-jlr200

PubMed ID: 16106050

Title: A human skin multifunctional O-acyltransferase that catalyzes the synthesis of acylglycerols, waxes, and retinyl esters.

PubMed ID: 16106050

DOI: 10.1194/jlr.m500168-jlr200

PubMed ID: 17035227

Title: Membrane topology and identification of key functional amino acid residues of murine acyl-CoA:diacylglycerol acyltransferase-2.

PubMed ID: 17035227

DOI: 10.1074/jbc.m607986200

PubMed ID: 21680734

Title: Murine diacylglycerol acyltransferase-2 (DGAT2) can catalyze triacylglycerol synthesis and promote lipid droplet formation independent of its localization to the endoplasmic reticulum.

PubMed ID: 21680734

DOI: 10.1074/jbc.m111.256008

PubMed ID: 23066022

Title: Studies on the substrate and stereo/regioselectivity of adipose triglyceride lipase, hormone-sensitive lipase, and diacylglycerol-O-acyltransferases.

PubMed ID: 23066022

DOI: 10.1074/jbc.m112.400416

PubMed ID: 22493088

Title: The use of stable isotope-labeled glycerol and oleic acid to differentiate the hepatic functions of DGAT1 and -2.

PubMed ID: 22493088

DOI: 10.1194/jlr.m020156

Sequence Information:

  • Length: 388
  • Mass: 43770
  • Checksum: 9C35C37DCAF61D55
  • Sequence:
  • MKTLIAAYSG VLRGERRAEA ARSENKNKGS ALSREGSGRW GTGSSILSAL QDIFSVTWLN 
    RSKVEKQLQV ISVLQWVLSF LVLGVACSVI LMYTFCTDCW LIAVLYFTWL AFDWNTPKKG 
    GRRSQWVRNW AVWRYFRDYF PIQLVKTHNL LTTRNYIFGY HPHGIMGLGA FCNFSTEATE 
    VSKKFPGIRP YLATLAGNFR MPVLREYLMS GGICPVNRDT IDYLLSKNGS GNAIIIVVGG 
    AAESLSSMPG KNAVTLKNRK GFVKLALRHG ADLVPTYSFG ENEVYKQVIF EEGSWGRWVQ 
    KKFQKYIGFA PCIFHGRGLF SSDTWGLVPY SKPITTVVGE PITVPKLEHP TQKDIDLYHA 
    MYMEALVKLF DNHKTKFGLP ETEVLEVN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.