Derl1 | ENSMUSG00000022365 | NCBI 67819

Details for: Derl1

Gene ID: 67819

Symbol: Derl1

Ensembl ID: ENSMUSG00000022365

Description: Der1-like domain family, member 1

Associated with

Abc-family proteins mediated transport
(R-MMU-382556)
Asparagine n-linked glycosylation
(R-MMU-446203)
Metabolism of proteins
(R-MMU-392499)
N-glycan trimming in the er and calnexin/calreticulin cycle
(R-MMU-532668)
Post-translational protein modification
(R-MMU-597592)
Transport of small molecules
(R-MMU-382551)
Atpase binding
(GO:0051117)
Cellular response to misfolded protein
(GO:0071218)
Cellular response to unfolded protein
(GO:0034620)
Derlin-1 retrotranslocation complex
(GO:0036513)
Derlin-1-vimp complex
(GO:0036502)
Early endosome
(GO:0005769)
Endoplasmic reticulum
(GO:0005783)
Endoplasmic reticulum membrane
(GO:0005789)
Endoplasmic reticulum quality control compartment
(GO:0044322)
Endoplasmic reticulum unfolded protein response
(GO:0030968)
Erad pathway
(GO:0036503)
Hrd1p ubiquitin ligase erad-l complex
(GO:0000839)
Identical protein binding
(GO:0042802)
Late endosome
(GO:0005770)
Membrane
(GO:0016020)
Mhc class i protein binding
(GO:0042288)
Misfolded protein binding
(GO:0051787)
Positive regulation of protein ubiquitination
(GO:0031398)
Protease binding
(GO:0002020)
Proteasome-mediated ubiquitin-dependent protein catabolic process
(GO:0043161)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Protein destabilization
(GO:0031648)
Protein transport
(GO:0015031)
Response to unfolded protein
(GO:0006986)
Retrograde protein transport, er to cytosol
(GO:0030970)
Signal recognition particle binding
(GO:0005047)
Ubiquitin-specific protease binding
(GO:1990381)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

Degradation in endoplasmic reticulum protein 1

Genular Protein ID: 299503278

Symbol: DERL1_MOUSE

Name: Degradation in endoplasmic reticulum protein 1

UniProtKB Accession Codes:

Q99J56 Q3U6Z2 Q9D918

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16186509

Title: Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane.

PubMed ID: 16186509

DOI: 10.1073/pnas.0505014102

PubMed ID: 16449189

Title: Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation.

PubMed ID: 16449189

DOI: 10.1083/jcb.200507057

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22016385

Title: Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis.

PubMed ID: 22016385

DOI: 10.1074/jbc.m111.310920

PubMed ID: 22267725

Title: ERdj4 protein is a soluble endoplasmic reticulum (ER) DnaJ family protein that interacts with ER-associated degradation machinery.

PubMed ID: 22267725

DOI: 10.1074/jbc.m111.311290

PubMed ID: 24160817

Title: Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex.

PubMed ID: 24160817

DOI: 10.1042/bj20130710

PubMed ID: 25009997

Title: Contribution of calumin to embryogenesis through participation in the endoplasmic reticulum-associated degradation activity.

PubMed ID: 25009997

DOI: 10.1016/j.ydbio.2014.06.024

Sequence Information:

Length: 251
Mass: 28835
Checksum: 2E1B79DEAFD3FDC8
Sequence:

MSDIGDWFRS IPAITRYWFA ATVAVPLIGK LGIISPAYFF LWPEAFLYRF QIWRPFTATF 
YFPVGPGTGF LYLVNLYFLY QYSTRLEAGA FDGRPADYLF MLLFNWICIV ITGLAMDMQL 
LMIPLIMSVL YVWAQLNRDL IVSFWFGTRF KACYLPWVIL GFNYIIGGSV INELIGNLVG 
HLYFFLMFRY PMDLGGRNFL STPQFLYRWL PSRRGGVSGF GVPPASMRRA ADQNGGGGRH 
NWGQGFRLGD Q

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Derl1

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Multiprotein complexes that link dislocation, ubiquitination, and extraction of misfolded proteins from the endoplasmic reticulum membrane. PubMed ID: 16186509

Derlin-2 and Derlin-3 are regulated by the mammalian unfolded protein response and are required for ER-associated degradation. PubMed ID: 16449189

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Selenoprotein K binds multiprotein complexes and is involved in the regulation of endoplasmic reticulum homeostasis. PubMed ID: 22016385

ERdj4 protein is a soluble endoplasmic reticulum (ER) DnaJ family protein that interacts with ER-associated degradation machinery. PubMed ID: 22267725

Signal-peptide-mediated translocation is regulated by a p97-AIRAPL complex. PubMed ID: 24160817

Contribution of calumin to embryogenesis through participation in the endoplasmic reticulum-associated degradation activity. PubMed ID: 25009997