Rnf146 | ENSMUSG00000038876 | NCBI 68031

Details for: Rnf146

Gene ID: 68031

Symbol: Rnf146

Ensembl ID: ENSMUSG00000038876

Description: ring finger protein 146

Associated with

Degradation of axin
(R-MMU-4641257)
Deubiquitination
(R-MMU-5688426)
Intracellular signaling by second messengers
(R-MMU-9006925)
Metabolism of proteins
(R-MMU-392499)
Pip3 activates akt signaling
(R-MMU-1257604)
Post-translational protein modification
(R-MMU-597592)
Pten regulation
(R-MMU-6807070)
Regulation of pten stability and activity
(R-MMU-8948751)
Signaling by wnt
(R-MMU-195721)
Signal transduction
(R-MMU-162582)
Tcf dependent signaling in response to wnt
(R-MMU-201681)
Ub-specific processing proteases
(R-MMU-5689880)
Cellular response to hydrogen peroxide
(GO:0070301)
Cytoplasm
(GO:0005737)
Cytosol
(GO:0005829)
Enzyme binding
(GO:0019899)
Metal ion binding
(GO:0046872)
Negative regulation of cellular response to oxidative stress
(GO:1900408)
Nucleoplasm
(GO:0005654)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Poly-adp-d-ribose binding
(GO:0072572)
Positive regulation of canonical wnt signaling pathway
(GO:0090263)
Protein autoubiquitination
(GO:0051865)
Protein binding
(GO:0005515)
Protein k48-linked ubiquitination
(GO:0070936)
Transferase activity
(GO:0016740)
Ubiquitin-dependent protein catabolic process
(GO:0006511)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin protein ligase activity
(GO:0061630)
Wnt signaling pathway
(GO:0016055)
Zinc ion binding
(GO:0008270)

Other Information

Proteins

E3 ubiquitin-protein ligase RNF146
Q9CTM5_MOUSE

Genular Protein ID: 3644676196

Symbol: RN146_MOUSE

Name: E3 ubiquitin-protein ligase RNF146

UniProtKB Accession Codes:

Q9CZW6 E0CX97 Q3TF93 Q3U6Y7

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15813938

Title: The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease.

PubMed ID: 15813938

DOI: 10.1111/j.1460-9568.2005.03977.x

PubMed ID: 21602803

Title: Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death.

PubMed ID: 21602803

DOI: 10.1038/nm.2387

PubMed ID: 21825151

Title: Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage.

PubMed ID: 21825151

DOI: 10.1073/pnas.1108799108

Sequence Information:

Length: 359
Mass: 38934
Checksum: B4449DB4897A41E0
Sequence:

MEMAGCGEID HSINMLPTNK KANESCSNTA PSLTVPECAI CLQTCVHPVS LPCKHVFCYL 
CVKGASWLGK RCALCRQEIP EDFLDKPTLL SPEELKAASR GNGEYAWYYE GRNGWWQYDE 
RTSRELEDAF SKGKKNTEML IAGFLYVADL ENMVQYRRNE HGRRRKIKRD IIDIPKKGVA 
GLRLDCDTNT VNLARESSAD GADSGSAQTG ASVQLAVPSS TRPLTSVDGQ LTSPVTPSPD 
AGISLEDSFA HLQLSGDSIA ERSHRGEGEE DHESPSSGRV PDTSVEETES DASSDSEDAP 
VVVAQHSLTQ QRPLVPNGNQ TVADQSDRSG TDRSVAGGGT MSVNVRSRRP DGQCTVTEV

Genular Protein ID: 951626132

Symbol: Q9CTM5_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9CTM5

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 153
Mass: 16728
Checksum: 72D9C1483D2A2F75
Sequence:

MHVPLQLHLY YTHFKGYLVC FPFLAIASKF AGPPHSVSKT SRSFCNASSI YSSRAEQTDF 
FKPLMTCGGP LTNFSSHSCA CSRAVVSSEG CKTSSVKPIF KASLESSLRV PLNTLRACLL 
PMISTRRLVP PQLGTIPISL WTNLITLSSV INL

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Rnf146

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The novel cytosolic RING finger protein dactylidin is up-regulated in brains of patients with Alzheimer's disease. PubMed ID: 15813938

Iduna protects the brain from glutamate excitotoxicity and stroke by interfering with poly(ADP-ribose) polymer-induced cell death. PubMed ID: 21602803

Iduna is a poly(ADP-ribose) (PAR)-dependent E3 ubiquitin ligase that regulates DNA damage. PubMed ID: 21825151

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073