Details for: Akirin1

Gene ID: 68050

Symbol: Akirin1

Ensembl ID: ENSMUSG00000023075

Description: akirin 1

Associated with

  • Chromatin
    (GO:0000785)
  • Myoblast migration involved in skeletal muscle regeneration
    (GO:0014839)
  • Negative regulation of satellite cell differentiation
    (GO:1902725)
  • Negative regulation of skeletal muscle satellite cell proliferation
    (GO:1902723)
  • Nuclear membrane
    (GO:0031965)
  • Nucleoplasm
    (GO:0005654)
  • Nucleus
    (GO:0005634)
  • Positive regulation of lamellipodium assembly
    (GO:0010592)
  • Positive regulation of macrophage chemotaxis
    (GO:0010759)
  • Positive regulation of myoblast differentiation
    (GO:0045663)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Transcription coregulator activity
    (GO:0003712)

Other Information

Genular Protein ID: 2225168894

Symbol: AKIR1_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q99LF1 Q9JJB7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 8 Ensembl 1 GO 12 GeneTree 1 Genevisible 1 HOGENOM 1 InParanoid 1 InterPro 1 KEGG 1 MGI 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PaxDb 1 PeptideAtlas 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 RefSeq 1 SAM 1 SMR 1 STRING 1 TreeFam 1 UCSC 1 UniProtKB 2 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 18255059

Title: Mighty is a novel promyogenic factor in skeletal myogenesis.

PubMed ID: 18255059

DOI: 10.1016/j.yexcr.2008.01.004

PubMed ID: 18066067

Title: Akirins are highly conserved nuclear proteins required for NF-kappaB-dependent gene expression in Drosophila and mice.

PubMed ID: 18066067

DOI: 10.1038/ni1543

PubMed ID: 19406121

Title: Akirin1 (Mighty), a novel promyogenic factor regulates muscle regeneration and cell chemotaxis.

PubMed ID: 19406121

DOI: 10.1016/j.yexcr.2009.04.014

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 23516508

Title: Myostatin suppression of Akirin1 mediates glucocorticoid-induced satellite cell dysfunction.

PubMed ID: 23516508

DOI: 10.1371/journal.pone.0058554

PubMed ID: 30746755

Title: Role of Akirin1 in the regulation of skeletal muscle fiber-type switch.

PubMed ID: 30746755

DOI: 10.1002/jcb.28406

Sequence Information:

  • Length: 191
  • Mass: 21676
  • Checksum: 52AFC483184A86A7
  • Sequence:
    • MACGATLKRP MEFEAALLSP GSPKRRRCAP LPGPTPGLRP PDAEPPPLQM QTPPASLQQP 
APPGSERRLP TPEQIFQNIK QEYNRYQRWR HLEVVLSQSE ACTSETQPSS SALTAPGSPG 
AFWMKKDQPT FTLRQVGIIC ERLLKDYEDK VREEYEQILS TKLAEQYESF VKFTHDQIMR 
RYGTRPTSYV S

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.