Details for: Eif3h

Gene ID: 68135

Symbol: Eif3h

Ensembl ID: ENSMUSG00000022312

Description: eukaryotic translation initiation factor 3, subunit H

Associated with

  • Activation of the mrna upon binding of the cap-binding complex and eifs, and subsequent binding to 43s
    (R-MMU-72662)
  • Cap-dependent translation initiation
    (R-MMU-72737)
  • Eukaryotic translation initiation
    (R-MMU-72613)
  • Formation of a pool of free 40s subunits
    (R-MMU-72689)
  • Formation of the ternary complex, and subsequently, the 43s complex
    (R-MMU-72695)
  • Gtp hydrolysis and joining of the 60s ribosomal subunit
    (R-MMU-72706)
  • L13a-mediated translational silencing of ceruloplasmin expression
    (R-MMU-156827)
  • Metabolism of proteins
    (R-MMU-392499)
  • Ribosomal scanning and start codon recognition
    (R-MMU-72702)
  • Translation initiation complex formation
    (R-MMU-72649)
  • Cytoplasm
    (GO:0005737)
  • Eukaryotic 43s preinitiation complex
    (GO:0016282)
  • Eukaryotic translation initiation factor 3 complex
    (GO:0005852)
  • Eukaryotic translation initiation factor 3 complex, eif3m
    (GO:0071541)
  • Metal-dependent deubiquitinase activity
    (GO:0140492)
  • Metallopeptidase activity
    (GO:0008237)
  • Negative regulation of proteasomal ubiquitin-dependent protein catabolic process
    (GO:0032435)
  • Peptidase activity
    (GO:0008233)
  • Translation
    (GO:0006412)
  • Translational initiation
    (GO:0006413)
  • Translation initiation factor activity
    (GO:0003743)

Other Information

Genular Protein ID: 4252049840

Symbol: EIF3H_MOUSE

Name: eIF-3-gamma

UniProtKB Accession Codes:

Q91WK2

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 1 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 1 EPD 1 Ensembl 1 ExpressionAtlas 1 GO 11 Gene3D 1 GeneTree 1 Genevisible 1 HAMAP 1 HAMAP-Rule 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MEROPS 1 MGI 1 MINT 1 MaxQB 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PROSITE-ProRule 1 PaxDb 1 Pfam 2 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 Pumba 1 RNAct 1 Reactome 6 RefSeq 1 SAM 1 SMART 1 SMR 1 STRING 1 SwissPalm 1 TreeFam 1 UCSC 1 UniProtKB 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1

Citations:

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17581632

Title: Reconstitution reveals the functional core of mammalian eIF3.

PubMed ID: 17581632

DOI: 10.1038/sj.emboj.7601765

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26100019

Title: The DHX33 RNA Helicase Promotes mRNA Translation Initiation.

PubMed ID: 26100019

DOI: 10.1128/mcb.00315-15

Sequence Information:

  • Length: 352
  • Mass: 39832
  • Checksum: 96F5AB8E2F41F838
  • Sequence:
    • MASRKEGTGS TATSSGSAGG AVGKGKGKGG SGDSAVKQVQ IDGLVVLKII KHYQEEGQGT 
EVVQGVLLGL VVEDRLEITN CFPFPQHTED DADFDEVQYQ MEMMRSLRHV NIDHLHVGWY 
QSTYYGSFVT RALLDSQFSY QHAIEESVVL IYDPIKTAQG SLSLKAYRLT PKLMEVCKEK 
DFSPEALKKA SITFEHMFEE VPIVIKNSHL INVLMWELEK KSAVADKHEL LSLASSNHLG 
KSLQLLMDRV DEMSQDIIKY NTYMRNTSKQ QQQKHQYQQR RQQENMQRQS RGEPPLPEED 
LSKLFKPHQA PARMDSLLIA GQINTYCQNI KEFTAQNLGK LFMAQALQEY NN

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.