Arl13b | ENSMUSG00000022911 | NCBI 68146

Details for: Arl13b

Gene ID: 68146

Symbol: Arl13b

Ensembl ID: ENSMUSG00000022911

Description: ADP-ribosylation factor-like 13B

Associated with

Aggrephagy
(R-MMU-9646399)
Arl13b-mediated ciliary trafficking of inpp5e
(R-MMU-5624958)
Autophagy
(R-MMU-9612973)
Cargo trafficking to the periciliary membrane
(R-MMU-5620920)
Macroautophagy
(R-MMU-1632852)
Organelle biogenesis and maintenance
(R-MMU-1852241)
Rho gtpase cycle
(R-MMU-9012999)
Rhoq gtpase cycle
(R-MMU-9013406)
Selective autophagy
(R-MMU-9663891)
Signaling by rho gtpases
(R-MMU-194315)
Signaling by rho gtpases, miro gtpases and rhobtb3
(R-MMU-9716542)
Signal transduction
(R-MMU-162582)
Axoneme
(GO:0005930)
Cell projection
(GO:0042995)
Ciliary membrane
(GO:0060170)
Cilium
(GO:0005929)
Cilium assembly
(GO:0060271)
Cytosol
(GO:0005829)
Determination of left/right symmetry
(GO:0007368)
Dorsal/ventral pattern formation
(GO:0009953)
Formation of radial glial scaffolds
(GO:0021943)
Gtpase activity
(GO:0003924)
Gtp binding
(GO:0005525)
Heart looping
(GO:0001947)
Interneuron migration from the subpallium to the cortex
(GO:0021830)
Left/right axis specification
(GO:0070986)
Membrane
(GO:0016020)
Motile cilium
(GO:0031514)
Multicellular organism development
(GO:0007275)
Neural tube patterning
(GO:0021532)
Non-motile cilium
(GO:0097730)
Non-motile cilium assembly
(GO:1905515)
Nucleotide binding
(GO:0000166)
Plasma membrane
(GO:0005886)
Protein binding
(GO:0005515)
Receptor localization to non-motile cilium
(GO:0097500)
Smoothened signaling pathway
(GO:0007224)

Other Information

Proteins

ADP-ribosylation factor-like protein 13B
Q9CUD0_MOUSE

Genular Protein ID: 2436230656

Symbol: AR13B_MOUSE

Name: ADP-ribosylation factor-like protein 13B

UniProtKB Accession Codes:

Q640N2 G3X9K5

Database IDs:

Citations:

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 17488627

Title: The graded response to Sonic Hedgehog depends on cilia architecture.

PubMed ID: 17488627

DOI: 10.1016/j.devcel.2007.03.004

PubMed ID: 19144319

Title: The phagosomal proteome in interferon-gamma-activated macrophages.

PubMed ID: 19144319

DOI: 10.1016/j.immuni.2008.11.006

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 20643351

Title: Pitchfork regulates primary cilia disassembly and left-right asymmetry.

PubMed ID: 20643351

DOI: 10.1016/j.devcel.2010.06.005

PubMed ID: 20231383

Title: Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans.

PubMed ID: 20231383

DOI: 10.1083/jcb.200908133

PubMed ID: 21539826

Title: Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13b hnn stems from abnormal Shh signaling.

PubMed ID: 21539826

DOI: 10.1016/j.ydbio.2011.04.019

PubMed ID: 21976698

Title: Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins.

PubMed ID: 21976698

DOI: 10.1091/mbc.e10-12-0994

PubMed ID: 22554696

Title: Defective Nodal and Cerl2 expression in the Arl13b(hnn) mutant node underlie its heterotaxia.

PubMed ID: 22554696

DOI: 10.1016/j.ydbio.2012.04.011

PubMed ID: 23153492

Title: Arl13b in primary cilia regulates the migration and placement of interneurons in the developing cerebral cortex.

PubMed ID: 23153492

DOI: 10.1016/j.devcel.2012.09.019

PubMed ID: 23014696

Title: Temporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over time.

PubMed ID: 23014696

DOI: 10.1242/dev.082321

PubMed ID: 24120134

Title: Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division.

PubMed ID: 24120134

DOI: 10.1016/j.cell.2013.08.060

PubMed ID: 23817546

Title: Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation.

PubMed ID: 23817546

DOI: 10.1038/nn.3451

PubMed ID: 24339792

Title: Active transport and diffusion barriers restrict Joubert syndrome-associated ARL13B/ARL-13 to an inv-like ciliary membrane subdomain.

PubMed ID: 24339792

DOI: 10.1371/journal.pgen.1003977

PubMed ID: 25138100

Title: Identification of a novel ARL13B variant in a Joubert syndrome-affected patient with retinal impairment and obesity.

PubMed ID: 25138100

DOI: 10.1038/ejhg.2014.156

PubMed ID: 26582389

Title: Arl13b and the exocyst interact synergistically in ciliogenesis.

PubMed ID: 26582389

DOI: 10.1091/mbc.e15-02-0061

Sequence Information:

Length: 427
Mass: 48144
Checksum: AC131D386B999ABB
Sequence:

MFSLMANCCN LFKRWREPVR KVTLVMVGLD NAGKTATAKG IQGEHPEDVA PTVGFSKIDL 
RQGKFQVTIF DLGGGKRIRG IWKNYYAESY GVIFVVDSSD EERMEETKET MSEVLRHPRI 
SGKPILVLAN KQDKEGALGE ADVIECLSLE KLVNEHKCLC QIEPCSAVLG YGKKIDKSIK 
KGLYWLLHII AKDFDALSER IQKDTTEQRA LEEQEKRERA ERVRKLREER EREQTELDGT 
SGLAEIDSGP VLANPFQPIA AVIIENEKKQ EKEKKKQTVE KDSDVGLLEH KVEPEQAAPQ 
SEADCCLQNP DERVVDSYRE ALSQQLDSED EQDQRGSESG ENSKKKTKKL RMKRSHRVEP 
VNTDESTPKS PTPPQPPPPV GWGTPKVTRL PKLEPLGETR HNDFYGKPLP PLAVRQRPNG 
DAQDTIS

Genular Protein ID: 3080880327

Symbol: Q9CUD0_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q9CUD0

Database IDs:

Citations:

PubMed ID: 10349636

Title: High-efficiency full-length cDNA cloning.

PubMed ID: 10349636

DOI: 10.1016/S0076-6879(99)03004-9

PubMed ID: 11042159

Title: Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes.

PubMed ID: 11042159

DOI: 10.1101/gr.145100

PubMed ID: 11076861

Title: RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer.

PubMed ID: 11076861

DOI: 10.1101/gr.152600

PubMed ID: 11217851

Title: Functional annotation of a full-length mouse cDNA collection.

PubMed ID: 11217851

DOI: 10.1038/35055500

PubMed ID: 12466851

Title: Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs.

PubMed ID: 12466851

DOI: 10.1038/nature01266

PubMed ID: 16141073

Title: Antisense Transcription in the Mammalian Transcriptome.

PubMed ID: 16141073

DOI: 10.1126/science.1112009

Sequence Information:

Length: 269
Mass: 30406
Checksum: 74465112B9BCBB20
Sequence:

MFSLMANCCN LFKRWREPVR KVTLVMVGLD NAGKTATAKG IQGEHPEDVA PTVGFSKIDL 
RQGKFQVTIF DLGGGKRIRG IWKNYYAESY GVIFVVDSSD EERMEETKET MSEVLRHPRI 
SGKPILVLAN KQDKEGALGE ADVIECLSLE KLVNEHKCLC QIEPCSAVLG YGKKIDKSIK 
KGLYWLLHII AKDFDALSER IQKDTTEQRA LEEQEKRERA ERVRKLREER EREQTELDGT 
SGLAEIDSGP VLANPFQPIA AVIIENEKK

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Arl13b

Associated with

Other Information

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

The graded response to Sonic Hedgehog depends on cilia architecture. PubMed ID: 17488627

The phagosomal proteome in interferon-gamma-activated macrophages. PubMed ID: 19144319

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Pitchfork regulates primary cilia disassembly and left-right asymmetry. PubMed ID: 20643351

Joubert syndrome Arl13b functions at ciliary membranes and stabilizes protein transport in Caenorhabditis elegans. PubMed ID: 20231383

Disrupted dorsal neural tube BMP signaling in the cilia mutant Arl13b hnn stems from abnormal Shh signaling. PubMed ID: 21539826

Arl13b regulates ciliogenesis and the dynamic localization of Shh signaling proteins. PubMed ID: 21976698

Defective Nodal and Cerl2 expression in the Arl13b(hnn) mutant node underlie its heterotaxia. PubMed ID: 22554696

Arl13b in primary cilia regulates the migration and placement of interneurons in the developing cerebral cortex. PubMed ID: 23153492

Temporal deletion of Arl13b reveals that a mispatterned neural tube corrects cell fate over time. PubMed ID: 23014696

Asymmetric inheritance of centrosome-associated primary cilium membrane directs ciliogenesis after cell division. PubMed ID: 24120134

Arl13b-regulated cilia activities are essential for polarized radial glial scaffold formation. PubMed ID: 23817546

Active transport and diffusion barriers restrict Joubert syndrome-associated ARL13B/ARL-13 to an inv-like ciliary membrane subdomain. PubMed ID: 24339792

Identification of a novel ARL13B variant in a Joubert syndrome-affected patient with retinal impairment and obesity. PubMed ID: 25138100

Arl13b and the exocyst interact synergistically in ciliogenesis. PubMed ID: 26582389

High-efficiency full-length cDNA cloning. PubMed ID: 10349636

Normalization and subtraction of cap-trapper-selected cDNAs to prepare full-length cDNA libraries for rapid discovery of new genes. PubMed ID: 11042159

RIKEN integrated sequence analysis (RISA) system--384-format sequencing pipeline with 384 multicapillary sequencer. PubMed ID: 11076861

Functional annotation of a full-length mouse cDNA collection. PubMed ID: 11217851

Analysis of the mouse transcriptome based on functional annotation of 60,770 full-length cDNAs. PubMed ID: 12466851

Antisense Transcription in the Mammalian Transcriptome. PubMed ID: 16141073