Details for: BSG

Gene ID: 682

Symbol: BSG

Ensembl ID: ENSG00000172270

Description: basigin (Ok blood group)

Associated with

Cells (max top 100)

(Marker Score score is uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: kidney loop of Henle thick ascending limb epithelial cell (CL1001106)
    Fold Change: 3.95
    Marker Score: 10599
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: 3.79
    Marker Score: 7996.5
  • Cell Name: kidney collecting duct principal cell (CL1001431)
    Fold Change: 3.51
    Marker Score: 8850
  • Cell Name: kidney collecting duct intercalated cell (CL1001432)
    Fold Change: 3.4
    Marker Score: 5634
  • Cell Name: renal intercalated cell (CL0005010)
    Fold Change: 3.23
    Marker Score: 1722
  • Cell Name: colon epithelial cell (CL0011108)
    Fold Change: 3.21
    Marker Score: 10076
  • Cell Name: acinar cell (CL0000622)
    Fold Change: 3.2
    Marker Score: 2254
  • Cell Name: mesodermal cell (CL0000222)
    Fold Change: 3.17
    Marker Score: 41770
  • Cell Name: kidney loop of Henle thin ascending limb epithelial cell (CL1001107)
    Fold Change: 3.06
    Marker Score: 3106
  • Cell Name: myeloid leukocyte (CL0000766)
    Fold Change: 3.02
    Marker Score: 3644
  • Cell Name: alveolar capillary type 2 endothelial cell (CL4028003)
    Fold Change: 2.99
    Marker Score: 4325.5
  • Cell Name: mesothelial cell of epicardium (CL0011019)
    Fold Change: 2.95
    Marker Score: 946
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: 2.94
    Marker Score: 3554
  • Cell Name: endocrine cell (CL0000163)
    Fold Change: 2.9
    Marker Score: 1501
  • Cell Name: interstitial cell of ovary (CL0002094)
    Fold Change: 2.9
    Marker Score: 18865
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 2.87
    Marker Score: 99485
  • Cell Name: type G enteroendocrine cell (CL0000508)
    Fold Change: 2.85
    Marker Score: 983
  • Cell Name: glycinergic amacrine cell (CL4030028)
    Fold Change: 2.84
    Marker Score: 2683
  • Cell Name: decidual cell (CL2000002)
    Fold Change: 2.84
    Marker Score: 12255
  • Cell Name: kidney distal convoluted tubule epithelial cell (CL1000849)
    Fold Change: 2.81
    Marker Score: 2980
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: 2.8
    Marker Score: 5698
  • Cell Name: neuroblast (sensu Vertebrata) (CL0000031)
    Fold Change: 2.78
    Marker Score: 1747
  • Cell Name: epithelial cell of proximal tubule (CL0002306)
    Fold Change: 2.76
    Marker Score: 9807
  • Cell Name: supporting cell (CL0000630)
    Fold Change: 2.75
    Marker Score: 5175
  • Cell Name: epithelial cell of nephron (CL1000449)
    Fold Change: 2.75
    Marker Score: 5733
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 2.74
    Marker Score: 1712.5
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 2.74
    Marker Score: 30823
  • Cell Name: epithelial cell of lower respiratory tract (CL0002632)
    Fold Change: 2.69
    Marker Score: 11200
  • Cell Name: decidual natural killer cell, human (CL0002343)
    Fold Change: 2.68
    Marker Score: 7410.5
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 2.68
    Marker Score: 10337.5
  • Cell Name: mucous neck cell (CL0000651)
    Fold Change: 2.67
    Marker Score: 6059
  • Cell Name: regular ventricular cardiac myocyte (CL0002131)
    Fold Change: 2.65
    Marker Score: 59326
  • Cell Name: kidney connecting tubule epithelial cell (CL1000768)
    Fold Change: 2.65
    Marker Score: 3750
  • Cell Name: Mueller cell (CL0000636)
    Fold Change: 2.64
    Marker Score: 3656
  • Cell Name: cerebral cortex endothelial cell (CL1001602)
    Fold Change: 2.63
    Marker Score: 1570
  • Cell Name: erythroid progenitor cell (CL0000038)
    Fold Change: 2.62
    Marker Score: 2736
  • Cell Name: migratory enteric neural crest cell (CL0002607)
    Fold Change: 2.62
    Marker Score: 2462
  • Cell Name: ovarian surface epithelial cell (CL2000064)
    Fold Change: 2.6
    Marker Score: 7085.5
  • Cell Name: fibroblast of lung (CL0002553)
    Fold Change: 2.56
    Marker Score: 6706
  • Cell Name: endocardial cell (CL0002350)
    Fold Change: 2.56
    Marker Score: 1445
  • Cell Name: mesenchymal cell (CL0008019)
    Fold Change: 2.55
    Marker Score: 4340.5
  • Cell Name: myofibroblast cell (CL0000186)
    Fold Change: 2.55
    Marker Score: 3147
  • Cell Name: lung endothelial cell (CL1001567)
    Fold Change: 2.55
    Marker Score: 22372
  • Cell Name: neural crest cell (CL0011012)
    Fold Change: 2.53
    Marker Score: 2709
  • Cell Name: foveolar cell of stomach (CL0002179)
    Fold Change: 2.53
    Marker Score: 16125
  • Cell Name: retinal rod cell (CL0000604)
    Fold Change: 2.53
    Marker Score: 7206
  • Cell Name: enterocyte (CL0000584)
    Fold Change: 2.52
    Marker Score: 12106
  • Cell Name: uterine smooth muscle cell (CL0002601)
    Fold Change: 2.5
    Marker Score: 3258.5
  • Cell Name: granulosa cell (CL0000501)
    Fold Change: 2.49
    Marker Score: 25013
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 2.48
    Marker Score: 591.5
  • Cell Name: erythroid lineage cell (CL0000764)
    Fold Change: 2.45
    Marker Score: 1221
  • Cell Name: lung ciliated cell (CL1000271)
    Fold Change: 2.44
    Marker Score: 1160
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: 2.44
    Marker Score: 83112.5
  • Cell Name: Sertoli cell (CL0000216)
    Fold Change: 2.43
    Marker Score: 14438.5
  • Cell Name: kidney interstitial cell (CL1000500)
    Fold Change: 2.43
    Marker Score: 1730
  • Cell Name: kidney cell (CL1000497)
    Fold Change: 2.43
    Marker Score: 1620
  • Cell Name: blood cell (CL0000081)
    Fold Change: 2.42
    Marker Score: 28171
  • Cell Name: epithelial cell (CL0000066)
    Fold Change: 2.42
    Marker Score: 3842
  • Cell Name: interstitial cell of Cajal (CL0002088)
    Fold Change: 2.41
    Marker Score: 836
  • Cell Name: endothelial cell (CL0000115)
    Fold Change: 2.41
    Marker Score: 2159
  • Cell Name: mature gamma-delta T cell (CL0000800)
    Fold Change: 2.39
    Marker Score: 7550
  • Cell Name: basal cell of prostate epithelium (CL0002341)
    Fold Change: 2.38
    Marker Score: 5819
  • Cell Name: peripheral nervous system neuron (CL2000032)
    Fold Change: 2.38
    Marker Score: 2673
  • Cell Name: enteroendocrine cell (CL0000164)
    Fold Change: 2.37
    Marker Score: 1229
  • Cell Name: NKp46-positive innate lymphoid cell, human (CL0001076)
    Fold Change: 2.37
    Marker Score: 6913.5
  • Cell Name: pneumocyte (CL0000322)
    Fold Change: 2.36
    Marker Score: 3799
  • Cell Name: enteric smooth muscle cell (CL0002504)
    Fold Change: 2.36
    Marker Score: 5562
  • Cell Name: basal cell of epithelium of trachea (CL1000348)
    Fold Change: 2.35
    Marker Score: 17519
  • Cell Name: club cell (CL0000158)
    Fold Change: 2.34
    Marker Score: 2736
  • Cell Name: secretory cell (CL0000151)
    Fold Change: 2.33
    Marker Score: 4257
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: 2.33
    Marker Score: 1200
  • Cell Name: kidney loop of Henle epithelial cell (CL1000909)
    Fold Change: 2.33
    Marker Score: 1460
  • Cell Name: photoreceptor cell (CL0000210)
    Fold Change: 2.32
    Marker Score: 1748
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 2.32
    Marker Score: 41165
  • Cell Name: Unknown (CL0002371)
    Fold Change: 2.32
    Marker Score: 2463
  • Cell Name: endothelial cell of uterus (CL0009095)
    Fold Change: 2.31
    Marker Score: 4614.5
  • Cell Name: lung secretory cell (CL1000272)
    Fold Change: 2.31
    Marker Score: 2060.5
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: 2.31
    Marker Score: 59076.5
  • Cell Name: Unknown (CL0000548)
    Fold Change: 2.3
    Marker Score: 1678
  • Cell Name: smooth muscle cell (CL0000192)
    Fold Change: 2.3
    Marker Score: 1513
  • Cell Name: mesenchymal stem cell (CL0000134)
    Fold Change: 2.3
    Marker Score: 3536
  • Cell Name: PP cell (CL0000696)
    Fold Change: 2.3
    Marker Score: 517
  • Cell Name: type EC enteroendocrine cell (CL0000577)
    Fold Change: 2.29
    Marker Score: 2161
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: 2.28
    Marker Score: 8970
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: 2.28
    Marker Score: 2409
  • Cell Name: reticular cell (CL0000432)
    Fold Change: 2.28
    Marker Score: 830.5
  • Cell Name: P/D1 enteroendocrine cell (CL0002268)
    Fold Change: 2.27
    Marker Score: 847
  • Cell Name: mature T cell (CL0002419)
    Fold Change: 2.27
    Marker Score: 22496
  • Cell Name: capillary endothelial cell (CL0002144)
    Fold Change: 2.27
    Marker Score: 2441
  • Cell Name: inhibitory motor neuron (CL0008015)
    Fold Change: 2.27
    Marker Score: 1071
  • Cell Name: fibroblast (CL0000057)
    Fold Change: 2.26
    Marker Score: 2179
  • Cell Name: pericyte (CL0000669)
    Fold Change: 2.25
    Marker Score: 1316
  • Cell Name: stem cell (CL0000034)
    Fold Change: 2.25
    Marker Score: 5348
  • Cell Name: primary sensory neuron (sensu Teleostei) (CL0000531)
    Fold Change: 2.25
    Marker Score: 756
  • Cell Name: CD4-positive, alpha-beta cytotoxic T cell (CL0000934)
    Fold Change: 2.25
    Marker Score: 1974
  • Cell Name: IgA plasma cell (CL0000987)
    Fold Change: 2.24
    Marker Score: 1908
  • Cell Name: bronchus fibroblast of lung (CL2000093)
    Fold Change: 2.23
    Marker Score: 3063
  • Cell Name: stromal cell (CL0000499)
    Fold Change: 2.22
    Marker Score: 2601
  • Cell Name: bronchial epithelial cell (CL0002328)
    Fold Change: 2.22
    Marker Score: 587.5
  • Cell Name: motor neuron (CL0000100)
    Fold Change: 2.21
    Marker Score: 1312.5

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Other Information

**Key characteristics** * BSG is a cell surface protein that is highly expressed on endothelial cells and some immune cells. * It is a member of the immunoglobulin superfamily, which are involved in cell adhesion, signaling, and immune responses. * BSG is a type I transmembrane protein, meaning it has both extracellular and intracellular domains. * It is responsible for the recognition of the B blood group antigen by immune cells. **Pathways and functions** * BSG is involved in several pathways that are important for maintaining blood homeostasis, including: * Aspirin adme pathway: BSG is a key regulator of the aspirin adme pathway, an inflammatory response that is involved in tissue repair and inflammation. * Basigin interactions: BSG interacts with other proteins on the cell surface, including CD49a and CD62, which are involved in cell adhesion and immune responses. * Cell surface interactions at the vascular wall: BSG is expressed on the surface of vascular endothelial cells, where it plays a role in maintaining blood flow and preventing the leakage of fluid and proteins into the extracellular environment. * Defective slc16a1 causes symptomatic deficiency in lactate transport (sdlt): BSG is a key regulator of the function of the SLC16A1 protein, which is responsible for the transport of lactate, a waste product of anaerobic metabolism, out of the cells. When SLC16A1 is mutated, it leads to the accumulation of lactate in the blood, which can cause a variety of symptoms, including fatigue, weakness, and shortness of breath. **Clinical significance** Mutations in the BSG gene have been linked to several human diseases, including: * Blood disorders: Mutations in BSG can lead to the formation of unstable blood group antigens, which can cause blood type incompatibility. * Cardiovascular disease: BSG mutations have also been linked to an increased risk of cardiovascular disease, likely through their role in maintaining blood flow and preventing the development of blood clots. * Cancer: BSG mutations have been found in a number of human cancers, where they can promote tumor growth and invasion.

Genular Protein ID: 2548920936

Symbol: BASI_HUMAN

Name: 5F7

UniProtKB Accession Codes:

P35613 A6NJW1 D3YLG5 Q7Z796 Q8IZL7

Database IDs:

ABCD 1 AGR 1 AlphaFoldDB 1 Antibodypedia 1 BMRB 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 3 CDD 1 CORUM 1 CPTAC 2 CTD 1 ChEMBL 1 ChiTaRS 1 DIP 1 DMDM 1 DNASU 1 DisGeNET 1 EMBL 23 EMDB 6 EPD 1 Ensembl 7 EvolutionaryTrace 1 ExpressionAtlas 1 GO 37 Gene3D 1 GeneCards 1 GeneTree 1 GeneWiki 1 Genevisible 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 2 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 2 MINT 1 MassIVE 1 MaxQB 1 MetOSite 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PDB 32 PDBsum 16 PIR 1 PRO 1 PROSITE 1 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 Pumba 1 RNAct 1 Reactome 7 RefSeq 6 SAM 1 SIGNOR 1 SMART 2 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TCDB 1 TopDownProteomics 3 TreeFam 1 UCSC 1 UniProtKB 4 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 1634773

Title: Human leukocyte activation antigen M6, a member of the Ig superfamily, is the species homologue of rat OX-47, mouse basigin, and chicken HT7 molecule.

PubMed ID: 1634773

PubMed ID: 1783610

Title: The basigin group of the immunoglobulin superfamily: complete conservation of a segment in and around transmembrane domains of human and mouse basigin and chicken HT7 antigen.

PubMed ID: 1783610

DOI: 10.1093/oxfordjournals.jbchem.a123657

PubMed ID: 7812975

Title: The human tumor cell-derived collagenase stimulatory factor (renamed EMMPRIN) is a member of the immunoglobulin superfamily.

PubMed ID: 7812975

PubMed ID: 9767135

Title: Characterization of the gene for human EMMPRIN, a tumor cell surface inducer of matrix metalloproteinases.

PubMed ID: 9767135

DOI: 10.1016/s0378-1119(98)00400-4

PubMed ID: 12939332

Title: Retina-specific expression of 5A11/Basigin-2, a member of the immunoglobulin gene superfamily.

PubMed ID: 12939332

DOI: 10.1167/iovs.02-0995

PubMed ID: 21536654

Title: Characterization of basigin isoforms and the inhibitory function of basigin-3 in human hepatocellular carcinoma proliferation and invasion.

PubMed ID: 21536654

DOI: 10.1128/mcb.05160-11

PubMed ID: 12975309

Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.

PubMed ID: 12975309

DOI: 10.1101/gr.1293003

PubMed ID: 15057824

Title: The DNA sequence and biology of human chromosome 19.

PubMed ID: 15057824

DOI: 10.1038/nature02399

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15340161

Title: Signal peptide prediction based on analysis of experimentally verified cleavage sites.

PubMed ID: 15340161

DOI: 10.1110/ps.04682504

PubMed ID: 1846736

Title: Partial sequencing and characterization of the tumor cell-derived collagenase stimulatory factor.

PubMed ID: 1846736

DOI: 10.1016/0003-9861(91)90332-d

PubMed ID: 11688976

Title: CD147 is a signaling receptor for cyclophilin B.

PubMed ID: 11688976

DOI: 10.1006/bbrc.2001.5847

PubMed ID: 11353871

Title: CD147 facilitates HIV-1 infection by interacting with virus-associated cyclophilin A.

PubMed ID: 11353871

DOI: 10.1073/pnas.111583198

PubMed ID: 12553375

Title: EMMPRIN-mediated MMP regulation in tumor and endothelial cells.

PubMed ID: 12553375

DOI: 10.1023/a:1021350718226

PubMed ID: 11992541

Title: Basigin (CD147) is expressed on melanoma cells and induces tumor cell invasion by stimulating production of matrix metalloproteinases by fibroblasts.

PubMed ID: 11992541

DOI: 10.1002/ijc.10390

PubMed ID: 11943775

Title: Active site residues of cyclophilin A are crucial for its signaling activity via CD147.

PubMed ID: 11943775

DOI: 10.1074/jbc.m201593200

PubMed ID: 12792908

Title: Basigin (CD147): a multifunctional transmembrane protein involved in reproduction, neural function, inflammation and tumor invasion.

PubMed ID: 12792908

DOI: 10.14670/hh-18.981

PubMed ID: 12754519

Title: Identification and quantification of N-linked glycoproteins using hydrazide chemistry, stable isotope labeling and mass spectrometry.

PubMed ID: 12754519

DOI: 10.1038/nbt827

PubMed ID: 15833850

Title: Extracellular matrix metalloproteinase inducer stimulates tumor angiogenesis by elevating vascular endothelial cell growth factor and matrix metalloproteinases.

PubMed ID: 15833850

DOI: 10.1158/0008-5472.can-04-3605

PubMed ID: 15688292

Title: Function of HAb18G/CD147 in invasion of host cells by severe acute respiratory syndrome coronavirus.

PubMed ID: 15688292

DOI: 10.1086/427811

PubMed ID: 15946952

Title: Cell surface expression of CD147/EMMPRIN is regulated by cyclophilin 60.

PubMed ID: 15946952

DOI: 10.1074/jbc.m503770200

PubMed ID: 17081983

Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.

PubMed ID: 17081983

DOI: 10.1016/j.cell.2006.09.026

PubMed ID: 17081065

Title: Proteomic and bioinformatic characterization of the biogenesis and function of melanosomes.

PubMed ID: 17081065

DOI: 10.1021/pr060363j

PubMed ID: 17127621

Title: The role of charged residues in the transmembrane helices of monocarboxylate transporter 1 and its ancillary protein basigin in determining plasma membrane expression and catalytic activity.

PubMed ID: 17127621

DOI: 10.1080/09687860600841967

PubMed ID: 17267690

Title: junction protein shrew-1 influences cell invasion and interacts with invasion-promoting protein CD147.

PubMed ID: 17267690

DOI: 10.1091/mbc.e06-07-0637

PubMed ID: 19413330

Title: Lys-N and trypsin cover complementary parts of the phosphoproteome in a refined SCX-based approach.

PubMed ID: 19413330

DOI: 10.1021/ac9004309

PubMed ID: 19837976

Title: EMMPRIN promotes angiogenesis through hypoxia-inducible factor-2alpha-mediated regulation of soluble VEGF isoforms and their receptor VEGFR-2.

PubMed ID: 19837976

DOI: 10.1182/blood-2009-04-217380

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 19349973

Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.

PubMed ID: 19349973

DOI: 10.1038/nbt.1532

PubMed ID: 20147391

Title: CD147/EMMPRIN acts as a functional entry receptor for measles virus on epithelial cells.

PubMed ID: 20147391

DOI: 10.1128/jvi.02168-09

PubMed ID: 20068231

Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.

PubMed ID: 20068231

DOI: 10.1126/scisignal.2000475

PubMed ID: 21269460

Title: Initial characterization of the human central proteome.

PubMed ID: 21269460

DOI: 10.1186/1752-0509-5-17

PubMed ID: 21778275

Title: Juvenile cataract-associated mutation of solute carrier SLC16A12 impairs trafficking of the protein to the plasma membrane.

PubMed ID: 21778275

DOI: 10.1167/iovs.10-6579

PubMed ID: 21245143

Title: Cyclophilin A (CyPA) induces chemotaxis independent of its peptidylprolyl cis-trans isomerase activity: direct binding between CyPA and the ectodomain of CD147.

PubMed ID: 21245143

DOI: 10.1074/jbc.c110.181347

PubMed ID: 22080952

Title: Basigin is a receptor essential for erythrocyte invasion by Plasmodium falciparum.

PubMed ID: 22080952

DOI: 10.1038/nature10606

PubMed ID: 21406692

Title: System-wide temporal characterization of the proteome and phosphoproteome of human embryonic stem cell differentiation.

PubMed ID: 21406692

DOI: 10.1126/scisignal.2001570

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 24297912

Title: RH5-Basigin interaction plays a major role in the host tropism of Plasmodium falciparum.

PubMed ID: 24297912

DOI: 10.1073/pnas.1320771110

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 25957687

Title: Rod-derived cone viability factor promotes cone survival by stimulating aerobic glycolysis.

PubMed ID: 25957687

DOI: 10.1016/j.cell.2015.03.023

PubMed ID: 26195724

Title: Basigin is a druggable target for host-oriented antimalarial interventions.

PubMed ID: 26195724

DOI: 10.1084/jem.20150032

PubMed ID: 25825981

Title: EMMPRIN/CD147 is a novel coreceptor of VEGFR-2 mediating its activation by VEGF.

PubMed ID: 25825981

DOI: 10.18632/oncotarget.2870

PubMed ID: 25944712

Title: N-terminome analysis of the human mitochondrial proteome.

PubMed ID: 25944712

DOI: 10.1002/pmic.201400617

PubMed ID: 27503893

Title: Xkr8 phospholipid scrambling complex in apoptotic phosphatidylserine exposure.

PubMed ID: 27503893

DOI: 10.1073/pnas.1610403113

PubMed ID: 28666119

Title: Type 2 diabetes variants disrupt function of SLC16A11 through two distinct mechanisms.

PubMed ID: 28666119

DOI: 10.1016/j.cell.2017.06.011

PubMed ID: 28409866

Title: P. falciparum RH5-Basigin interaction induces changes in the cytoskeleton of the host RBC.

PubMed ID: 28409866

DOI: 10.1111/cmi.12747

PubMed ID: 29739904

Title: CD147 Promotes Entry of Pentamer-Expressing Human Cytomegalovirus into Epithelial and Endothelial Cells.

PubMed ID: 29739904

DOI: 10.1128/mbio.00781-18

PubMed ID: 32307653

Title: CD147 as a Target for COVID-19 Treatment: Suggested Effects of Azithromycin and Stem Cell Engagement.

PubMed ID: 32307653

DOI: 10.1007/s12015-020-09976-7

PubMed ID: 33432067

Title: No evidence for basigin/CD147 as a direct SARS-CoV-2 spike binding receptor.

PubMed ID: 33432067

DOI: 10.1038/s41598-020-80464-1

PubMed ID: 18430721

Title: Crystal structure of HAb18G/CD147: implications for immunoglobulin superfamily homophilic adhesion.

PubMed ID: 18430721

DOI: 10.1074/jbc.m802694200

PubMed ID: 19768682

Title: Structure of the EMMPRIN N-terminal domain 1: dimerization via beta-strand swapping.

PubMed ID: 19768682

DOI: 10.1002/prot.22577

PubMed ID: 21620857

Title: The retinal specific CD147 Ig0 domain: from molecular structure to biological activity.

PubMed ID: 21620857

DOI: 10.1016/j.jmb.2011.04.060

PubMed ID: 25132548

Title: Structure of malaria invasion protein RH5 with erythrocyte basigin and blocking antibodies.

PubMed ID: 25132548

DOI: 10.1038/nature13715

PubMed ID: 33333023

Title: Structural basis of human monocarboxylate transporter 1 inhibition by anti-cancer drug candidates.

PubMed ID: 33333023

DOI: 10.1016/j.cell.2020.11.043

PubMed ID: 9130641

Title: The Ok(a) blood group antigen is a marker for the M6 leukocyte activation antigen, the human homolog of OX-47 antigen, basigin and neurothelin, an immunoglobulin superfamily molecule that is widely expressed in human cells and tissues.

PubMed ID: 9130641

DOI: 10.1002/eji.1830270414

PubMed ID: 32867305

Title: COVID-19 and Genetic Variants of Protein Involved in the SARS-CoV-2 Entry into the Host Cells.

PubMed ID: 32867305

DOI: 10.3390/genes11091010

Sequence Information:

  • Length: 385
  • Mass: 42200
  • Checksum: D74C37455BF26685
  • Sequence:
    • MAAALFVLLG FALLGTHGAS GAAGFVQAPL SQQRWVGGSV ELHCEAVGSP VPEIQWWFEG 
QGPNDTCSQL WDGARLDRVH IHATYHQHAA STISIDTLVE EDTGTYECRA SNDPDRNHLT 
RAPRVKWVRA QAVVLVLEPG TVFTTVEDLG SKILLTCSLN DSATEVTGHR WLKGGVVLKE 
DALPGQKTEF KVDSDDQWGE YSCVFLPEPM GTANIQLHGP PRVKAVKSSE HINEGETAML 
VCKSESVPPV TDWAWYKITD SEDKALMNGS ESRFFVSSSQ GRSELHIENL NMEADPGQYR 
CNGTSSKGSD QAIITLRVRS HLAALWPFLG IVAEVLVLVT IIFIYEKRRK PEDVLDDDDA 
GSAPLKSSGQ HQNDKGKNVR QRNSS

Genular Protein ID: 2335838124

Symbol: Q54A51_HUMAN

Name: N/A

UniProtKB Accession Codes:

Q54A51

Database IDs:

Antibodypedia 1 BioGRID-ORCS 1 CTD 1 ChiTaRS 1 DNASU 1 EMBL 6 ExpressionAtlas 1 GO 1 Gene3D 1 GenomeRNAi 1 IntAct 1 InterPro 4 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 1 PROSITE 2 Pfam 1 PharmGKB 1 RefSeq 2 SAM 3 SMART 1 SMR 1 SUPFAM 1 UCSC 1 VEuPathDB 1

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

Sequence Information:

  • Length: 269
  • Mass: 29221
  • Checksum: 0C9D6BEB966AC258
  • Sequence:
    • MAAALFVLLG FALLGTHGAS GAAGTVFTTV EDLGSKILLT CSLNDSATEV TGHRWLKGGV 
VLKEDALPGQ KTEFKVDSDD QWGEYSCVFL PEPMGTANIQ LHGPPRVKAV KSSEHINEGE 
TAMLVCKSES VPPVTDWAWY KITDSEDKAL MNGSESRFFV SSSQGRSELH IENLNMEADP 
GQYRCNGTSS KGSDQAIITL RVRSHLAALW PFLGIVAEVL VLVTIIFIYE KRRKPEDVLD 
DDDAGSAPLK SSGQHQNDKG KNVRQRNSS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. For the full schema, download it here.