Mul1 | ENSMUSG00000041241 | NCBI 68350

Details for: Mul1

Gene ID: 68350

Symbol: Mul1

Ensembl ID: ENSMUSG00000041241

Description: mitochondrial ubiquitin ligase activator of NFKB 1

Associated with

Cellular responses to stimuli
(R-MMU-8953897)
Cellular responses to stress
(R-MMU-2262752)
Cellular response to chemical stress
(R-MMU-9711123)
Deubiquitination
(R-MMU-5688426)
Keap1-nfe2l2 pathway
(R-MMU-9755511)
Metabolism of proteins
(R-MMU-392499)
Neddylation
(R-MMU-8951664)
Post-translational protein modification
(R-MMU-597592)
Ub-specific processing proteases
(R-MMU-5689880)
Activation of cysteine-type endopeptidase activity involved in apoptotic process
(GO:0006919)
Apoptotic process
(GO:0006915)
Axon
(GO:0030424)
Cellular response to exogenous dsrna
(GO:0071360)
Identical protein binding
(GO:0042802)
Membrane
(GO:0016020)
Metal ion binding
(GO:0046872)
Mitochondrial fission
(GO:0000266)
Mitochondrial outer membrane
(GO:0005741)
Mitochondrion
(GO:0005739)
Mitochondrion localization
(GO:0051646)
Negative regulation of cell growth
(GO:0030308)
Negative regulation of chemokine (c-c motif) ligand 5 production
(GO:0071650)
Negative regulation of defense response to virus by host
(GO:0050689)
Negative regulation of innate immune response
(GO:0045824)
Negative regulation of mitochondrial fusion
(GO:0010637)
Negative regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051898)
Negative regulation of type i interferon-mediated signaling pathway
(GO:0060339)
Neuronal cell body
(GO:0043025)
Organelle organization
(GO:0006996)
P53 binding
(GO:0002039)
Peroxisome
(GO:0005777)
Positive regulation of autophagy of mitochondrion in response to mitochondrial depolarization
(GO:1904925)
Positive regulation of dendrite extension
(GO:1903861)
Positive regulation of mitochondrial fission
(GO:0090141)
Positive regulation of protein sumoylation
(GO:0033235)
Protein destabilization
(GO:0031648)
Protein polyubiquitination
(GO:0000209)
Protein stabilization
(GO:0050821)
Protein ubiquitination
(GO:0016567)
Regulation of mitochondrial membrane potential
(GO:0051881)
Regulation of mitochondrial outer membrane permeabilization involved in apoptotic signaling pathway
(GO:1901028)
Regulation of mitochondrion organization
(GO:0010821)
Regulation of protein stability
(GO:0031647)
Sumo transferase activity
(GO:0019789)
Transferase activity
(GO:0016740)
Ubiquitin-protein transferase activity
(GO:0004842)
Ubiquitin protein ligase activity
(GO:0061630)
Ubiquitin protein ligase binding
(GO:0031625)

Other Information

Proteins

Mitochondrial ubiquitin ligase activator of NFKB 1

Genular Protein ID: 2492657282

Symbol: MUL1_MOUSE

Name: Mitochondrial ubiquitin ligase activator of NFKB 1

UniProtKB Accession Codes:

Q8VCM5 A2AM82 A2AM84 B5M498 Q3TDK4 Q8BHF2 Q9DCV9

Database IDs:

Citations:

PubMed ID: 18591963

Title: GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth.

PubMed ID: 18591963

DOI: 10.1038/cr.2008.75

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 24898855

Title: MUL1 acts in parallel to the PINK1/parkin pathway in regulating mitofusin and compensates for loss of PINK1/parkin.

PubMed ID: 24898855

DOI: 10.7554/elife.01958

Sequence Information:

Length: 352
Mass: 39835
Checksum: 252530F1BD917871
Sequence:

MESGSRPSLG QVILLGTSSM VTAVLYSIYR QKAQVAQELK GAKKIHLGED LKGILSEAPG 
KCVPYAVIEG AVRSVKETLN SQFVENCKGV IQRLSLQEHK MVWNRTTHLW NDYSKIIHQR 
TNTVPFDLVP HEDGVAVSVR VLKPLDSVDL GLETVYEKFH PSVQSFTDAI GHYISGERPK 
GIQETEEMLK VGATLTGIGE LVLDNNAVRL QPPKQGMQYY LSSQDFDSLL HRQESSVRLW 
KILVLVFGFA TCATLFFILR KQYLHRQERL RQQQLQEEFL EHEAQLLSQA SPEDRESLKS 
ACVVCLSNFK SCVFLECGHV CSCRQCYLAL PEPKRCPICR REITRVIPLY NS

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Mul1

Associated with

Other Information

GIDE is a mitochondrial E3 ubiquitin ligase that induces apoptosis and slows growth. PubMed ID: 18591963

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079