Details for: BST2
Associated with
Other Information
Genular Protein ID: 1351465413
Symbol: BST2_HUMAN
Name: Bone marrow stromal antigen 2
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 7607676
Title: Molecular cloning and chromosomal mapping of a bone marrow stromal cell surface gene, BST2, that may be involved in pre-B-cell growth.
PubMed ID: 7607676
PubMed ID: 10329429
Title: Molecular cloning and characterization of a surface antigen preferentially overexpressed on multiple myeloma cells.
PubMed ID: 10329429
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057824
Title: The DNA sequence and biology of human chromosome 19.
PubMed ID: 15057824
DOI: 10.1038/nature02399
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 16157322
Title: Characterization of antibodies submitted to the B cell section of the 8th Human Leukocyte Differentiation Antigens Workshop by flow cytometry and immunohistochemistry.
PubMed ID: 16157322
PubMed ID: 16602701
Title: Modification-specific proteomics of plasma membrane proteins: identification and characterization of glycosylphosphatidylinositol-anchored proteins released upon phospholipase D treatment.
PubMed ID: 16602701
DOI: 10.1021/pr050419u
PubMed ID: 17566972
Title: Computational approach for identification and characterization of GPI-anchored peptides in proteomics experiments.
PubMed ID: 17566972
PubMed ID: 18342597
Title: The interferon-induced protein BST-2 restricts HIV-1 release and is downregulated from the cell surface by the viral Vpu protein.
PubMed ID: 18342597
PubMed ID: 18200009
Title: Tetherin inhibits retrovirus release and is antagonized by HIV-1 Vpu.
PubMed ID: 18200009
DOI: 10.1038/nature06553
PubMed ID: 19879838
Title: Tetherin inhibits HIV-1 release by directly tethering virions to cells.
PubMed ID: 19879838
PubMed ID: 19917491
Title: A tail of Tetherin: how pandemic HIV-1 conquered the world.
PubMed ID: 19917491
PubMed ID: 19837671
Title: HIV-1 accessory protein Vpu internalizes cell-surface BST-2/tetherin through transmembrane interactions leading to lysosomes.
PubMed ID: 19837671
PubMed ID: 19564354
Title: Regulation of TLR7/9 responses in plasmacytoid dendritic cells by BST2 and ILT7 receptor interaction.
PubMed ID: 19564354
DOI: 10.1084/jem.20090547
PubMed ID: 19159218
Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.
PubMed ID: 19159218
DOI: 10.1021/pr8008012
PubMed ID: 19036818
Title: Broad-spectrum inhibition of retroviral and filoviral particle release by tetherin.
PubMed ID: 19036818
DOI: 10.1128/jvi.02211-08
PubMed ID: 19740980
Title: Antagonism to and intracellular sequestration of human tetherin by the human immunodeficiency virus type 2 envelope glycoprotein.
PubMed ID: 19740980
DOI: 10.1128/jvi.01515-09
PubMed ID: 19349973
Title: Mass-spectrometric identification and relative quantification of N-linked cell surface glycoproteins.
PubMed ID: 19349973
DOI: 10.1038/nbt.1532
PubMed ID: 19179289
Title: Tetherin-mediated restriction of filovirus budding is antagonized by the Ebola glycoprotein.
PubMed ID: 19179289
PubMed ID: 19737401
Title: The formation of cysteine-linked dimers of BST-2/tetherin is important for inhibition of HIV-1 virus release but not for sensitivity to Vpu.
PubMed ID: 19737401
PubMed ID: 20686043
Title: Infectious Lassa virus, but not filoviruses, is restricted by BST-2/tetherin.
PubMed ID: 20686043
DOI: 10.1128/jvi.00103-10
PubMed ID: 20943977
Title: Interferon-induced cell membrane proteins, IFITM3 and tetherin, inhibit vesicular stomatitis virus infection via distinct mechanisms.
PubMed ID: 20943977
DOI: 10.1128/jvi.01328-10
PubMed ID: 20419159
Title: The RING-CH ligase K5 antagonizes restriction of KSHV and HIV-1 particle release by mediating ubiquitin-dependent endosomal degradation of tetherin.
PubMed ID: 20419159
PubMed ID: 20688520
Title: BST-2/tetherin: a new component of the innate immune response to enveloped viruses.
PubMed ID: 20688520
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 22180752
Title: structural basis for the antiviral activity of Bst-2/tetherin and its viral antagonism.
PubMed ID: 22180752
PubMed ID: 21166593
Title: The interferon-inducible host factor bone marrow stromal antigen 2/tetherin restricts virion release, but is it actually a viral restriction factor?
PubMed ID: 21166593
PubMed ID: 21222046
PubMed ID: 21529378
Title: Tetherin inhibits prototypic foamy virus release.
PubMed ID: 21529378
PubMed ID: 21621240
Title: Influenza virus is not restricted by tetherin whereas influenza VLP production is restricted by tetherin.
PubMed ID: 21621240
PubMed ID: 21994744
Title: Antiviral inhibition of enveloped virus release by tetherin/BST-2: action and counteraction.
PubMed ID: 21994744
DOI: 10.3390/v3050520
PubMed ID: 22509177
PubMed ID: 22065321
Title: BST-2 binding with cellular MT1-MMP blocks cell growth and migration via decreasing MMP2 activity.
PubMed ID: 22065321
DOI: 10.1002/jcb.23433
PubMed ID: 22811908
Title: Restriction of retroviral replication by tetherin/BST-2.
PubMed ID: 22811908
DOI: 10.1155/2012/424768
PubMed ID: 23028328
Title: Identification of alternatively translated Tetherin isoforms with differing antiviral and signaling activities.
PubMed ID: 23028328
PubMed ID: 22814378
Title: N-terminal acetylome analyses and functional insights of the N-terminal acetyltransferase NatB.
PubMed ID: 22814378
PubMed ID: 22520941
Title: Modulation of hepatitis C virus release by the interferon-induced protein BST-2/tetherin.
PubMed ID: 22520941
PubMed ID: 26172439
Title: Vpu exploits the cross-talk between BST2 and the ILT7 receptor to suppress anti-HIV-1 responses by plasmacytoid dendritic Cells.
PubMed ID: 26172439
PubMed ID: 26378163
Title: Severe Acute Respiratory Syndrome Coronavirus ORF7a Inhibits Bone Marrow Stromal Antigen 2 Virion Tethering through a Novel Mechanism of Glycosylation Interference.
PubMed ID: 26378163
DOI: 10.1128/jvi.02274-15
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 31199522
Title: Severe acute respiratory syndrome coronavirus spike protein counteracts BST2-mediated restriction of virus-like particle release.
PubMed ID: 31199522
DOI: 10.1002/jmv.25518
PubMed ID: 20399176
Title: Structural basis of HIV-1 tethering to membranes by the BST-2/tetherin ectodomain.
PubMed ID: 20399176
PubMed ID: 20880831
Title: Structural and functional studies on the extracellular domain of BST2/tetherin in reduced and oxidized conformations.
PubMed ID: 20880831
PubMed ID: 20940320
Title: Structural insight into the mechanisms of enveloped virus tethering by tetherin.
PubMed ID: 20940320
Sequence Information:
- Length: 180
- Mass: 19769
- Checksum: CAF52340D69061EE
- Sequence:
MASTSYDYCR VPMEDGDKRC KLLLGIGILV LLIIVILGVP LIIFTIKANS EACRDGLRAV MECRNVTHLL QQELTEAQKG FQDVEAQAAT CNHTVMALMA SLDAEKAQGQ KKVEELEGEI TTLNHKLQDA SAEVERLRRE NQVLSVRIAD KKYYPSSQDS SSAAAPQLLI VLLGLSALLQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.