Details for: KLF9
Gene ID: 687
Gene Type: Protein-coding - A gene that serves as a template for producing a messenger RNA (mRNA) molecule, which is then translated into a functional protein.
Symbol: KLF9
Ensembl ID: ENSG00000119138
Description: KLF transcription factor 9
Selected Context(s): Overall
Cell Significance Landscape
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 30.98rCSI 74.48%PRS 54.27
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CSI 19.02rCSI 17.17%PRS 40.87
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CSI 18.6rCSI 25.43%PRS 49.01
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CSI 17.86rCSI 28.21%PRS 45.13
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CSI 15.45rCSI 81.2%PRS 52.59
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CSI 14.7rCSI 40.39%PRS 59.48
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CSI 14.53rCSI 42.08%PRS 46.6
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CSI 13.85rCSI 12.29%PRS 43.24
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CSI 12.63rCSI 10.26%PRS 44.87
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CSI 12.41rCSI 19.81%PRS 47.87
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CSI 11.3rCSI 15.37%PRS 56.89
-
CSI 11.25rCSI 15.58%PRS 49.08
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CSI 11.1rCSI 9.57%PRS 52.63
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CSI 9.24rCSI 22.06%PRS 54.67
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CSI 9.15rCSI 6.16%PRS 54.24
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CSI 9.12rCSI 20.46%PRS 29.68
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CSI 9.11rCSI 42.65%PRS 62.84
-
CSI 9.03rCSI 6.76%PRS 58.66
-
CSI 8.06rCSI 6.25%PRS 44.56
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CSI 8.04rCSI 17.79%PRS 41.53
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CSI 8.02rCSI 8.78%PRS 47.94
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CSI 7.96rCSI 44.16%PRS 67.33
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CSI 7.82rCSI 6.88%PRS 33.69
-
CSI 7.58rCSI 15.73%PRS 42.06
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CSI 7.5rCSI 7.09%PRS 45.1
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CSI 7.32rCSI 42.57%PRS 55.18
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CSI 7.19rCSI 20.61%PRS 61.6
-
CSI 6.95rCSI 38.75%PRS 62.19
-
CSI 6.81rCSI 30.8%PRS 71.42
-
CSI 6.58rCSI 6.08%PRS 64.26
-
CSI 6.49rCSI 52.82%PRS 38.88
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CSI 6.46rCSI 12.32%PRS 60.72
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CSI 6.37rCSI 17.91%PRS 44.3
-
CSI 6.09rCSI 4.55%PRS 62.54
-
CSI 5.81rCSI 11.51%PRS 66.97
-
CSI 5.79rCSI 4.55%PRS 50.52
-
CSI 5.68rCSI 39.03%PRS 62.32
-
CSI 5.57rCSI 4%PRS 56.93
-
CSI 5.53rCSI 10.14%PRS 66.78
-
CSI 5.19rCSI 16.82%PRS 46.88
-
CSI 4.99rCSI 17.97%PRS 27.96
-
CSI 4.83rCSI 5.58%PRS 34.64
-
CSI 4.76rCSI 10.87%PRS 37.83
-
CSI 4.66rCSI 6.61%PRS 41.21
-
CSI 4.55rCSI 12.75%PRS 58.64
-
CSI 4.5rCSI 4.19%PRS 43.95
-
CSI 4.32rCSI 4.16%PRS 44.69
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CSI 4.31rCSI 6.58%PRS 44.81
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CSI 4.19rCSI 5.38%PRS 39.81
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CSI 4.18rCSI 11.42%PRS 72.35
-
CSI 4.12rCSI 6.1%PRS 49.09
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CSI 4.1rCSI 17.02%PRS 53.55
-
CSI 4.06rCSI 3.02%PRS 57.18
-
CSI 3.91rCSI 2.72%PRS 52.55
-
CSI 3.87rCSI 5.92%PRS 53.19
-
CSI 3.8rCSI 4.59%PRS 51.83
-
CSI 3.65rCSI 5.61%PRS 51.04
-
CSI 3.64rCSI 9.4%PRS 40.49
-
CSI 3.41rCSI 5.07%PRS 46.7
-
CSI 3.4rCSI 3.4%PRS 38.6
-
CSI 3.37rCSI 3.79%PRS 60.47
-
CSI 3.28rCSI 13.22%PRS 42.68
-
CSI 3.23rCSI 5.7%PRS 52.67
-
CSI 3.23rCSI 8.42%PRS 52.46
-
CSI 3.17rCSI 2.35%PRS 38.01
-
CSI 3.11rCSI 6.31%PRS 27.29
-
CSI 3.03rCSI 58.53%PRS 68.85
-
CSI 3.02rCSI 7.39%PRS 40.31
-
CSI 3.01rCSI 8.56%PRS 44.14
-
CSI 2.97rCSI 5.21%PRS 36.73
-
CSI 2.95rCSI 16.9%PRS 56.3
-
CSI 2.81rCSI 2.14%PRS 55.37
-
CSI 2.8rCSI 6.28%PRS 64.02
-
CSI 2.76rCSI 4.77%PRS 35.18
-
CSI 2.75rCSI 1.82%PRS 47.91
-
CSI 2.74rCSI 12.23%PRS 67.18
-
CSI 2.64rCSI 2.7%PRS 62.63
-
CSI 2.62rCSI 8.19%PRS 30.18
-
CSI 2.61rCSI 2.7%PRS 49.92
-
CSI 2.55rCSI 4.05%PRS 54.72
-
CSI 2.55rCSI 6.3%PRS 42.19
-
CSI 2.49rCSI 5.15%PRS 50.55
-
CSI 2.47rCSI 1.92%PRS 60.85
-
CSI 2.43rCSI 11.64%PRS 45.69
-
CSI 2.42rCSI 3.24%PRS 45.66
-
CSI 2.39rCSI 10.03%PRS 65.79
-
CSI 2.38rCSI 6.28%PRS 51.62
-
CSI 2.36rCSI 8.85%PRS 37.47
-
CSI 2.31rCSI 22.71%PRS 71.04
-
CSI 2.29rCSI 5.05%PRS 48.06
-
CSI 2.27rCSI 4.08%PRS 37.75
-
CSI 2.25rCSI 12.92%PRS 69.83
-
CSI 2.25rCSI 5.15%PRS 43.53
-
CSI 2.21rCSI 1.83%PRS 42.65
-
CSI 2.2rCSI 6.36%PRS 61.78
-
CSI 2.18rCSI 2.81%PRS 29.9
-
CSI 2.13rCSI 5%PRS 53.28
-
CSI 2.09rCSI 1.58%PRS 56.31
-
CSI 2.03rCSI 5.47%PRS 52.89
-
CSI 2.02rCSI 2.36%PRS 59.6
-
CSI 0.2rCSI 1.1%PRS 36.9%
-
CSI 0.2rCSI 2.0%PRS 64.6%
-
CSI 0.3rCSI 4.1%PRS 68.8%
-
CSI 0.3rCSI 1.2%PRS 60.5%
-
CSI 0.3rCSI 1.8%PRS 66.5%
-
CSI 0.3rCSI 2.0%PRS 30.4%
-
CSI 0.4rCSI 2.2%PRS 55.1%
-
CSI 0.5rCSI 0.6%PRS 53.0%
-
CSI 0.6rCSI 2.9%PRS 58.8%
-
CSI 0.6rCSI 1.2%PRS 34.7%
-
CSI 0.6rCSI 1.1%PRS 60.4%
-
CSI 0.6rCSI 0.8%PRS 46.8%
-
CSI 0.6rCSI 1.0%PRS 29.0%
-
CSI 0.7rCSI 4.8%PRS 69.7%
-
CSI 0.7rCSI 5.3%PRS 62.3%
-
CSI 0.7rCSI 1.6%PRS 32.9%
-
CSI 0.7rCSI 4.3%PRS 58.1%
-
CSI 0.8rCSI 2.5%PRS 33.5%
-
CSI 0.8rCSI 1.8%PRS 34.0%
-
CSI 0.8rCSI 1.0%PRS 22.9%
-
CSI 0.8rCSI 1.0%PRS 39.7%
-
CSI 0.8rCSI 2.2%PRS 37.3%
-
CSI 0.8rCSI 7.4%PRS 72.7%
-
CSI 0.8rCSI 1.2%PRS 47.1%
-
CSI 0.9rCSI 4.6%PRS 59.4%
-
CSI 0.9rCSI 2.9%PRS 43.5%
-
CSI 0.9rCSI 2.6%PRS 41.0%
-
CSI 0.9rCSI 1.4%PRS 51.5%
-
CSI 1.0rCSI 2.1%PRS 59.1%
-
CSI 1.0rCSI 1.2%PRS 64.4%
-
CSI 1.0rCSI 7.6%PRS 64.4%
-
CSI 1.0rCSI 1.5%PRS 57.6%
-
CSI 1.0rCSI 1.2%PRS 29.0%
-
CSI 1.0rCSI 1.4%PRS 40.6%
-
CSI 1.0rCSI 1.5%PRS 60.3%
-
CSI 1.0rCSI 4.1%PRS 55.2%
-
CSI 1.1rCSI 1.1%PRS 46.9%
-
CSI 1.1rCSI 1.7%PRS 23.6%
-
CSI 1.1rCSI 3.3%PRS 56.1%
-
CSI 1.1rCSI 2.8%PRS 43.2%
-
CSI 1.1rCSI 2.6%PRS 28.2%
-
CSI 1.1rCSI 2.8%PRS 43.9%
-
CSI 1.1rCSI 1.5%PRS 35.8%
-
CSI 1.1rCSI 2.4%PRS 54.1%
-
CSI 1.1rCSI 2.2%PRS 43.5%
-
CSI 1.1rCSI 2.0%PRS 70.6%
-
CSI 1.1rCSI 0.9%PRS 43.0%
-
CSI 1.2rCSI 4.4%PRS 30.0%
-
CSI 1.2rCSI 1.8%PRS 41.0%
-
CSI 1.2rCSI 27.9%PRS 28.5%
-
CSI 1.2rCSI 1.4%PRS 54.8%
-
CSI 1.2rCSI 1.5%PRS 27.6%
-
CSI 1.2rCSI 4.7%PRS 53.0%
-
CSI 1.2rCSI 2.2%PRS 27.4%
-
CSI 1.2rCSI 1.1%PRS 53.4%
-
CSI 1.3rCSI 2.6%PRS 66.3%
-
CSI 1.3rCSI 7.5%PRS 70.4%
-
CSI 1.3rCSI 6.0%PRS 66.6%
-
CSI 1.3rCSI 2.5%PRS 67.2%
-
CSI 1.3rCSI 3.0%PRS 50.7%
-
CSI 1.4rCSI 32.7%PRS 29.4%
-
CSI 1.4rCSI 5.9%PRS 59.7%
-
CSI 1.4rCSI 1.8%PRS 57.1%
-
CSI 1.4rCSI 1.7%PRS 46.8%
-
CSI 1.4rCSI 1.9%PRS 52.6%
-
CSI 1.4rCSI 1.9%PRS 48.9%
-
CSI 1.5rCSI 3.5%PRS 59.9%
-
CSI 1.5rCSI 1.2%PRS 49.1%
-
CSI 1.5rCSI 5.8%PRS 59.4%
-
CSI 1.5rCSI 2.4%PRS 35.2%
-
CSI 1.5rCSI 5.7%PRS 37.8%
-
CSI 1.5rCSI 4.0%PRS 66.7%
-
CSI 1.5rCSI 2.5%PRS 49.7%
-
CSI 1.5rCSI 6.2%PRS 41.7%
-
CSI 1.6rCSI 2.9%PRS 34.3%
-
CSI 1.6rCSI 1.2%PRS 47.5%
-
CSI 1.6rCSI 2.0%PRS 48.9%
-
CSI 1.6rCSI 7.4%PRS 63.4%
-
CSI 1.6rCSI 1.5%PRS 51.5%
-
CSI 1.7rCSI 5.3%PRS 41.1%
-
CSI 1.7rCSI 2.4%PRS 46.8%
-
CSI 1.7rCSI 38.6%PRS 66.9%
-
CSI 1.7rCSI 1.3%PRS 66.1%
-
CSI 1.7rCSI 2.6%PRS 46.2%
-
CSI 1.7rCSI 1.8%PRS 41.5%
-
CSI 1.7rCSI 2.2%PRS 57.7%
-
CSI 1.8rCSI 4.4%PRS 52.4%
-
CSI 1.8rCSI 3.2%PRS 42.5%
-
CSI 1.8rCSI 8.6%PRS 42.6%
-
CSI 1.8rCSI 1.8%PRS 59.4%
-
CSI 1.9rCSI 2.8%PRS 40.3%
-
CSI 1.9rCSI 2.0%PRS 42.2%
-
CSI 1.9rCSI 1.3%PRS 56.8%
-
CSI 1.9rCSI 3.4%PRS 28.1%
-
CSI 1.9rCSI 1.1%PRS 59.1%
-
CSI 1.9rCSI 3.1%PRS 37.5%
-
CSI 2.0rCSI 2.4%PRS 59.6%
-
CSI 2.0rCSI 5.5%PRS 52.9%
-
CSI 2.1rCSI 1.6%PRS 56.3%
-
CSI 2.1rCSI 5.0%PRS 53.3%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Genular Protein ID: 3084599731
Symbol: KLF9_HUMAN
Name: Krueppel-like factor 9
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8291025
Title: Chromosomal localization and cDNA sequence of human BTEB, a GC box binding protein.
PubMed ID: 8291025
DOI: 10.1007/bf01233255
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15164053
Title: DNA sequence and analysis of human chromosome 9.
PubMed ID: 15164053
DOI: 10.1038/nature02465
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8051167
Title: Cell-specific translational control of transcription factor BTEB expression. The role of an upstream AUG in the 5'-untranslated region.
PubMed ID: 8051167
PubMed ID: 22711835
Title: Kruppel-like factor 9 is a circadian transcription factor in human epidermis that controls proliferation of keratinocytes.
PubMed ID: 22711835
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 33227311
Title: ZZEF1 is a Histone Reader and Transcriptional Coregulator of Krueppel-Like Factors.
PubMed ID: 33227311
Sequence Information:
- Length: 244
- Mass: 27235
- Checksum: 2D1B5A5BB9D42221
- Sequence:
MSAAAYMDFV AAQCLVSISN RAAVPEHGVA PDAERLRLPE REVTKEHGDP GDTWKDYCTL VTIAKSLLDL NKYRPIQTPS VCSDSLESPD EDMGSDSDVT TESGSSPSHS PEERQDPGSA PSPLSLLHPG VAAKGKHASE KRHKCPYSGC GKVYGKSSHL KAHYRVHTGE RPFPCTWPDC LKKFSRSDEL TRHYRTHTGE KQFRCPLCEK RFMRSDHLTK HARRHTEFHP SMIKRSKKAL ANAL