Details for: KLF5
Associated with
Cells (max top 100)
(Marker Scores and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: basal cell of prostate epithelium (CL0002341)
Fold Change: 3.5
Marker Score: 8,551 - Cell Name: epithelial cell of urethra (CL1000296)
Fold Change: 3.45
Marker Score: 2,716 - Cell Name: conjunctival epithelial cell (CL1000432)
Fold Change: 3.23
Marker Score: 3,395 - Cell Name: colon epithelial cell (CL0011108)
Fold Change: 3.12
Marker Score: 9,805 - Cell Name: basal cell of epithelium of trachea (CL1000348)
Fold Change: 3.12
Marker Score: 23,209 - Cell Name: nasal mucosa goblet cell (CL0002480)
Fold Change: 2.85
Marker Score: 1,904 - Cell Name: foveolar cell of stomach (CL0002179)
Fold Change: 2.68
Marker Score: 17,122 - Cell Name: epithelial cell of esophagus (CL0002252)
Fold Change: 2.68
Marker Score: 23,119 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: 2.59
Marker Score: 3,822 - Cell Name: stem cell (CL0000034)
Fold Change: 2.58
Marker Score: 6,132 - Cell Name: mucous neck cell (CL0000651)
Fold Change: 2.54
Marker Score: 5,759 - Cell Name: stem cell of epidermis (CL1000428)
Fold Change: 2.5
Marker Score: 847 - Cell Name: enterocyte (CL0000584)
Fold Change: 2.49
Marker Score: 11,972 - Cell Name: squamous epithelial cell (CL0000076)
Fold Change: 2.47
Marker Score: 1,679 - Cell Name: stratified epithelial cell (CL0000079)
Fold Change: 2.43
Marker Score: 18,965 - Cell Name: epithelial cell of prostate (CL0002231)
Fold Change: 2.42
Marker Score: 1,681 - Cell Name: basal cell (CL0000646)
Fold Change: 2.37
Marker Score: 3,062 - Cell Name: secretory cell (CL0000151)
Fold Change: 2.33
Marker Score: 4,260 - Cell Name: intestine goblet cell (CL0019031)
Fold Change: 2.32
Marker Score: 2,222 - Cell Name: thyroid follicular cell (CL0002258)
Fold Change: 2.28
Marker Score: 1,784 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: 2.18
Marker Score: 2,469 - Cell Name: corneal epithelial cell (CL0000575)
Fold Change: 2.17
Marker Score: 2,399 - Cell Name: epithelial cell (CL0000066)
Fold Change: 2.16
Marker Score: 3,439 - Cell Name: respiratory goblet cell (CL0002370)
Fold Change: 2.13
Marker Score: 614 - Cell Name: bronchial goblet cell (CL1000312)
Fold Change: 2.11
Marker Score: 1,039 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: 2.07
Marker Score: 4,380 - Cell Name: epithelial cell of stratum germinativum of esophagus (CL1000447)
Fold Change: 2.01
Marker Score: 485 - Cell Name: duct epithelial cell (CL0000068)
Fold Change: 1.92
Marker Score: 897 - Cell Name: glandular cell of esophagus (CL0002657)
Fold Change: 1.9
Marker Score: 603 - Cell Name: intestinal crypt stem cell (CL0002250)
Fold Change: 1.88
Marker Score: 706 - Cell Name: taste receptor cell (CL0000209)
Fold Change: 1.87
Marker Score: 1,619 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: 1.87
Marker Score: 1,862 - Cell Name: cortical thymic epithelial cell (CL0002364)
Fold Change: 1.87
Marker Score: 6,912 - Cell Name: cell in vitro (CL0001034)
Fold Change: 1.86
Marker Score: 64,481 - Cell Name: luminal cell of prostate epithelium (CL0002340)
Fold Change: 1.86
Marker Score: 1,081 - Cell Name: ciliated columnar cell of tracheobronchial tree (CL0002145)
Fold Change: 1.82
Marker Score: 15,837 - Cell Name: lung secretory cell (CL1000272)
Fold Change: 1.77
Marker Score: 1,583 - Cell Name: lung goblet cell (CL1000143)
Fold Change: 1.77
Marker Score: 511 - Cell Name: medullary thymic epithelial cell (CL0002365)
Fold Change: 1.74
Marker Score: 2,859 - Cell Name: type I pneumocyte (CL0002062)
Fold Change: 1.74
Marker Score: 2,095 - Cell Name: type II pneumocyte (CL0002063)
Fold Change: 1.71
Marker Score: 11,124 - Cell Name: club cell (CL0000158)
Fold Change: 1.64
Marker Score: 1,916 - Cell Name: ciliated cell (CL0000064)
Fold Change: 1.63
Marker Score: 5,594 - Cell Name: multi-ciliated epithelial cell (CL0005012)
Fold Change: 1.55
Marker Score: 2,945 - Cell Name: enterocyte of colon (CL1000347)
Fold Change: 1.53
Marker Score: 2,363 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 1.49
Marker Score: 370 - Cell Name: mural cell (CL0008034)
Fold Change: 1.47
Marker Score: 168,162 - Cell Name: respiratory epithelial cell (CL0002368)
Fold Change: 1.44
Marker Score: 791 - Cell Name: epithelial cell of lung (CL0000082)
Fold Change: 1.42
Marker Score: 7,481 - Cell Name: papillary tips cell (CL1000597)
Fold Change: 1.41
Marker Score: 285 - Cell Name: placental villous trophoblast (CL2000060)
Fold Change: 1.38
Marker Score: 5,408 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: 1.37
Marker Score: 3,113 - Cell Name: sst GABAergic cortical interneuron (CL4023017)
Fold Change: 1.34
Marker Score: 26,692 - Cell Name: mucus secreting cell (CL0000319)
Fold Change: 1.3
Marker Score: 330 - Cell Name: keratinocyte (CL0000312)
Fold Change: 1.27
Marker Score: 1,064 - Cell Name: basal cell of epidermis (CL0002187)
Fold Change: 1.27
Marker Score: 555 - Cell Name: epithelial cell of alveolus of lung (CL0010003)
Fold Change: 1.27
Marker Score: 569 - Cell Name: kidney loop of Henle epithelial cell (CL1000909)
Fold Change: 1.24
Marker Score: 780 - Cell Name: type G enteroendocrine cell (CL0000508)
Fold Change: 1.24
Marker Score: 427 - Cell Name: lactocyte (CL0002325)
Fold Change: 1.23
Marker Score: 19,703 - Cell Name: precursor cell (CL0011115)
Fold Change: 1.17
Marker Score: 285 - Cell Name: pneumocyte (CL0000322)
Fold Change: 1.16
Marker Score: 1,864 - Cell Name: serous secreting cell (CL0000313)
Fold Change: 1.15
Marker Score: 461 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: 1.15
Marker Score: 592 - Cell Name: basal epithelial cell of prostatic duct (CL0002236)
Fold Change: 1.14
Marker Score: 1,010 - Cell Name: P/D1 enteroendocrine cell (CL0002268)
Fold Change: 1.13
Marker Score: 422 - Cell Name: paneth cell of colon (CL0009009)
Fold Change: 1.1
Marker Score: 317 - Cell Name: kidney collecting duct cell (CL1001225)
Fold Change: 1.06
Marker Score: 208 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 1.04
Marker Score: 251,766 - Cell Name: peptic cell (CL0000155)
Fold Change: 1.04
Marker Score: 434 - Cell Name: epithelial fate stem cell (CL0000036)
Fold Change: 1.01
Marker Score: 289 - Cell Name: cerebral cortex GABAergic interneuron (CL0010011)
Fold Change: 1
Marker Score: 71,784 - Cell Name: forebrain radial glial cell (CL0013000)
Fold Change: 1
Marker Score: 48,009 - Cell Name: absorptive cell (CL0000212)
Fold Change: 0.98
Marker Score: 30,403 - Cell Name: epithelial cell of lower respiratory tract (CL0002632)
Fold Change: 0.97
Marker Score: 4,059 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.96
Marker Score: 496 - Cell Name: BEST4+ intestinal epithelial cell, human (CL4030026)
Fold Change: 0.95
Marker Score: 451 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.95
Marker Score: 2,410 - Cell Name: intestinal epithelial cell (CL0002563)
Fold Change: 0.94
Marker Score: 1,534 - Cell Name: ovarian surface epithelial cell (CL2000064)
Fold Change: 0.94
Marker Score: 2,555 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.94
Marker Score: 1,776 - Cell Name: lung ciliated cell (CL1000271)
Fold Change: 0.93
Marker Score: 444 - Cell Name: transit amplifying cell (CL0009010)
Fold Change: 0.93
Marker Score: 5,324 - Cell Name: luminal epithelial cell of mammary gland (CL0002326)
Fold Change: 0.93
Marker Score: 1,640 - Cell Name: abnormal cell (CL0001061)
Fold Change: 0.91
Marker Score: 2,729 - Cell Name: male germ cell (CL0000015)
Fold Change: 0.91
Marker Score: 262 - Cell Name: oocyte (CL0000023)
Fold Change: 0.91
Marker Score: 224 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.91
Marker Score: 14,162 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: 0.89
Marker Score: 1,818 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.88
Marker Score: 318 - Cell Name: paneth cell (CL0000510)
Fold Change: 0.88
Marker Score: 610 - Cell Name: large intestine goblet cell (CL1000320)
Fold Change: 0.88
Marker Score: 232 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.87
Marker Score: 5,271 - Cell Name: skeletal muscle satellite stem cell (CL0008011)
Fold Change: 0.87
Marker Score: 928 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.81
Marker Score: 27,632 - Cell Name: early T lineage precursor (CL0002425)
Fold Change: 0.8
Marker Score: 611 - Cell Name: enteroendocrine cell (CL0000164)
Fold Change: 0.8
Marker Score: 413 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 0.77
Marker Score: 660 - Cell Name: enterocyte of epithelium proper of ileum (CL1000342)
Fold Change: 0.76
Marker Score: 219 - Cell Name: Cajal-Retzius cell (CL0000695)
Fold Change: 0.75
Marker Score: 387
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Marker Score to the Marker Score Threshold, indicating how much the gene expression has changed compared to a baseline.
Marker Score: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 240671694
Symbol: KLF5_HUMAN
Name: Krueppel-like factor 5
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10572182
Title: Isolation and characterization of a gene encoding human Kruppel-like factor 5 (IKLF): binding to the CAAT/GT box of the mouse lactoferrin gene promoter.
PubMed ID: 10572182
PubMed ID: 23134681
Title: Shaking the family tree: Identification of novel and biologically active alternatively spliced isoforms across the KLF family of transcription factors.
PubMed ID: 23134681
DOI: 10.1096/fj.12-220319
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15057823
Title: The DNA sequence and analysis of human chromosome 13.
PubMed ID: 15057823
DOI: 10.1038/nature02379
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 8479902
Title: cDNA cloning and transcriptional properties of a novel GC box-binding protein, BTEB2.
PubMed ID: 8479902
PubMed ID: 15735697
Title: Ubiquitin-proteasome degradation of KLF5 transcription factor in cancer and untransformed epithelial cells.
PubMed ID: 15735697
PubMed ID: 18039846
Title: Promoter region-specific histone incorporation by the novel histone chaperone ANP32B and DNA-binding factor KLF5.
PubMed ID: 18039846
DOI: 10.1128/mcb.01396-07
PubMed ID: 28112733
Title: Site-specific mapping of the human SUMO proteome reveals co-modification with phosphorylation.
PubMed ID: 28112733
DOI: 10.1038/nsmb.3366
PubMed ID: 31375868
Title: The evolution of the 9aaTAD domain in Sp2 proteins: inactivation with valines and intron reservoirs.
PubMed ID: 31375868
PubMed ID: 16959974
Title: The consensus coding sequences of human breast and colorectal cancers.
PubMed ID: 16959974
PubMed ID: 26079537
Title: Ataxin-3 like (ATXN3L), a member of the Josephin family of deubiquitinating enzymes, promotes breast cancer proliferation by deubiquitinating Krueppel-like factor 5 (KLF5).
PubMed ID: 26079537
Sequence Information:
- Length: 457
- Mass: 50792
- Checksum: 3BF12BE272716E57
- Sequence:
MATRVLSMSA RLGPVPQPPA PQDEPVFAQL KPVLGAANPA RDAALFPGEE LKHAHHRPQA QPAPAQAPQP AQPPATGPRL PPEDLVQTRC EMEKYLTPQL PPVPIIPEHK KYRRDSASVV DQFFTDTEGL PYSINMNVFL PDITHLRTGL YKSQRPCVTH IKTEPVAIFS HQSETTAPPP APTQALPEFT SIFSSHQTAA PEVNNIFIKQ ELPTPDLHLS VPTQQGHLYQ LLNTPDLDMP SSTNQTAAMD TLNVSMSAAM AGLNTHTSAV PQTAVKQFQG MPPCTYTMPS QFLPQQATYF PPSPPSSEPG SPDRQAEMLQ NLTPPPSYAA TIASKLAIHN PNLPTTLPVN SQNIQPVRYN RRSNPDLEKR RIHYCDYPGC TKVYTKSSHL KAHLRTHTGE KPYKCTWEGC DWRFARSDEL TRHYRKHTGA KPFQCGVCNR SFSRSDHLAL HMKRHQN
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.