Atp6ap2 | ENSMUSG00000031007 | NCBI 70495

Details for: Atp6ap2

Gene ID: 70495

Symbol: Atp6ap2

Ensembl ID: ENSMUSG00000031007

Description: ATPase, H+ transporting, lysosomal accessory protein 2

Associated with

Immune system
(R-MMU-168256)
Innate immune system
(R-MMU-168249)
Metabolism of angiotensinogen to angiotensins
(R-MMU-2022377)
Metabolism of proteins
(R-MMU-392499)
Neutrophil degranulation
(R-MMU-6798695)
Peptide hormone metabolism
(R-MMU-2980736)
Angiotensin maturation
(GO:0002003)
Apical plasma membrane
(GO:0016324)
Autophagosome membrane
(GO:0000421)
Axon
(GO:0030424)
Cell body
(GO:0044297)
Central nervous system maturation
(GO:0021626)
Clathrin-coated vesicle membrane
(GO:0030665)
Dendritic spine membrane
(GO:0032591)
Endoplasmic reticulum membrane
(GO:0005789)
Endosome membrane
(GO:0010008)
External side of plasma membrane
(GO:0009897)
Extracellular space
(GO:0005615)
Eye pigmentation
(GO:0048069)
Head morphogenesis
(GO:0060323)
Lysosomal lumen acidification
(GO:0007042)
Lysosomal membrane
(GO:0005765)
Lysosome
(GO:0005764)
Membrane
(GO:0016020)
Positive regulation of canonical wnt signaling pathway
(GO:0090263)
Positive regulation of transforming growth factor beta1 production
(GO:0032914)
Positive regulation of wnt signaling pathway
(GO:0030177)
Postsynaptic membrane
(GO:0045211)
Regulation of mapk cascade
(GO:0043408)
Rostrocaudal neural tube patterning
(GO:0021903)
Signaling receptor activity
(GO:0038023)
Synaptic vesicle lumen acidification
(GO:0097401)
Synaptic vesicle membrane
(GO:0030672)
Vacuolar proton-transporting v-type atpase, v0 domain
(GO:0000220)
Vacuolar proton-transporting v-type atpase complex
(GO:0016471)

Other Information

Proteins

Renin receptor

Genular Protein ID: 4270863368

Symbol: RENR_MOUSE

Name: Renin receptor

UniProtKB Accession Codes:

Q9CYN9 A2BDN5 Q8BVU6 Q91YU5

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 26376863

Title: Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration.

PubMed ID: 26376863

DOI: 10.1093/hmg/ddv380

PubMed ID: 29127204

Title: Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects.

PubMed ID: 29127204

DOI: 10.1084/jem.20170453

PubMed ID: 30985297

Title: ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration.

PubMed ID: 30985297

DOI: 10.1172/jci79990

Sequence Information:

Length: 350
Mass: 39092
Checksum: 3A90E0C586E7BAC7
Sequence:

MAVLVVLLFF LVAGALGNEF SILRSPGSVV FRNGNWPIPG DRIPDVAALS MGFSVKEDLS 
WPGLAVGNLF HRPRATIMVM VKGVDKLALP AGSVISYPLE NAVPFSLDSV ANSIHSLFSE 
ETPVVLQLAP SEERVYMVGK ANSVFEDLSV TLRQLRNRLF QENSLLNSLP LNSLSRNNEV 
DLLFLSELQV LHDISSLLSR HKHLAKDHSP DLYSLELAGL DELGKRYGED SEQFRDASKI 
LVDALQKFAD DMYSLYGGNA VVELVTVKSF DTSLVRKSRT ILEAKQENTQ SPYNLAYKYN 
LEYSVVFNLV LWIMIGLALA VIITSYNIWN MDPGYDSIIY RMTNQKIRID

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Atp6ap2

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

Lineage-specific biology revealed by a finished genome assembly of the mouse. PubMed ID: 19468303

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Conditional depletion of intellectual disability and Parkinsonism candidate gene ATP6AP2 in fly and mouse induces cognitive impairment and neurodegeneration. PubMed ID: 26376863

Mutations in the X-linked ATP6AP2 cause a glycosylation disorder with autophagic defects. PubMed ID: 29127204

ATP6AP2 variant impairs CNS development and neuronal survival to cause fulminant neurodegeneration. PubMed ID: 30985297