Details for: Prdm16

Gene ID: 70673

Symbol: Prdm16

Ensembl ID: ENSMUSG00000039410

Description: PR domain containing 16

Associated with

Other Information

Genular Protein ID: 2266762126

Symbol: PRD16_MOUSE

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 12816872

Title: A novel EVI1 gene family, MEL1, lacking a PR domain (MEL1S) is expressed mainly in t(1;3)(p36;q21)-positive AML and blocks G-CSF-induced myeloid differentiation.

PubMed ID: 12816872

DOI: 10.1182/blood-2002-12-3944

PubMed ID: 19468303

Title: Lineage-specific biology revealed by a finished genome assembly of the mouse.

PubMed ID: 19468303

DOI: 10.1371/journal.pbio.1000112

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15368895

Title: Prediction of the coding sequences of mouse homologues of KIAA gene: IV. The complete nucleotide sequences of 500 mouse KIAA-homologous cDNAs identified by screening of terminal sequences of cDNA clones randomly sampled from size-fractionated libraries.

PubMed ID: 15368895

DOI: 10.1093/dnares/11.3.205

PubMed ID: 17467076

Title: PRDM16/MEL1: a novel Smad binding protein expressed in murine embryonic orofacial tissue.

PubMed ID: 17467076

DOI: 10.1016/j.bbamcr.2007.03.016

PubMed ID: 17618855

Title: Transcriptional control of brown fat determination by PRDM16.

PubMed ID: 17618855

DOI: 10.1016/j.cmet.2007.06.001

PubMed ID: 18483224

Title: Regulation of the brown and white fat gene programs through a PRDM16/CtBP transcriptional complex.

PubMed ID: 18483224

DOI: 10.1101/gad.1666108

PubMed ID: 18719582

Title: PRDM16 controls a brown fat/skeletal muscle switch.

PubMed ID: 18719582

DOI: 10.1038/nature07182

PubMed ID: 19641492

Title: Initiation of myoblast to brown fat switch by a PRDM16-C/EBP-beta transcriptional complex.

PubMed ID: 19641492

DOI: 10.1038/nature08262

PubMed ID: 22939622

Title: Prdm3 and Prdm16 are H3K9me1 methyltransferases required for mammalian heterochromatin integrity.

PubMed ID: 22939622

DOI: 10.1016/j.cell.2012.06.048

PubMed ID: 23768516

Title: Fine mapping of the 1p36 deletion syndrome identifies mutation of PRDM16 as a cause of cardiomyopathy.

PubMed ID: 23768516

DOI: 10.1016/j.ajhg.2013.05.015

PubMed ID: 25578880

Title: Cold-inducible Zfp516 activates UCP1 transcription to promote browning of white fat and development of brown fat.

PubMed ID: 25578880

DOI: 10.1016/j.molcel.2014.12.005

Sequence Information:

  • Length: 1275
  • Mass: 140858
  • Checksum: 2F1F6B6C3EBFEC10
  • Sequence:
  • MRSKARARKL AKSDGDVVNN MYEPDPDLLA GQSAEEETED GILSPIPMGP PSPFPTSEDF 
    TPKEGSPYEA PVYIPEDIPI PPDFELRESS IPGAGLGIWA KRKMEIGERF GPYVVTPRAA 
    LKEADFGWEM LTDTEVSSQE SCIKKQISED LGSEKFCVDA NQAGSGSWLK YIRVACSCDD 
    QNLAMCQINE QIYYKVIKDI EPGEELLVHV KEGAYSLGVM APSLDEDPTF RCDECDELFQ 
    CRLDLRRHKK YACSSAGAQL YEGLGEELKP EGLGVGSDGQ AHECKDCERM FPNKYSLEQH 
    MIVHTEEREY KCDQCPKAFN WKSNLIRHQM SHDSGKRFEC ENCVKVFTDP SNLQRHIRSQ 
    HVGARAHACP DCGKTFATSS GLKQHKHIHS TVKPFICEVC HKSYTQFSNL CRHKRMHADC 
    RTQIKCKDCG QMFSTTSSLN KHRRFCEGKN HYTPGSIFTP GLPLTPSPMM DKTKPSPTLN 
    HGGLGFSEYF PSRPHPGSLP FSAAPPAFPA LTPGFPGIFP PSLYPRPPLL PPTPLLKSPL 
    NHAQDAKLPS PLGNPALPLV SAVSNSSQGA TAATGSEEKF DGRLEDAYAE KVKNRSPDMS 
    DGSDFEDINT TTGTDLDTTT GTGSDLDSDL DSDRDKGKDK GKPVESKPEF GGASVPPGAM 
    NSVAEVPAFY SQHSFFPPPE EQLLTASGAA GDSIKAIASI AEKYFGPGFM SMQEKKLGSL 
    PYHSVFPFQF LPNFPHSLYP FTDRALAHNL LVKAEPKSPR DALKVGGPSA ECPFDLTTKP 
    KEAKPALLAP KVPLIPSSGE EQPLDLSIGS RARASQNGGG REPRKNHVYG ERKPGVSEGL 
    PKVCPAQLPQ QPSLHYAKPS PFFMDPIYRV EKRKVADPVG VLKEKYLRPS PLLFHPQMSA 
    IETMTEKLES FAAMKADSGS SLQPLPHHPF NFRSPPPTLS DPILRKGKER YTCRYCGKIF 
    PRSANLTRHL RTHTGEQPYR CKYCDRSFSI SSNLQRHVRN IHNKEKPFKC HLCNRCFGQQ 
    TNLDRHLKKH EHEGAPVSQH SGVLTNHLGT SASSPTSESD NHALLDEKED SYFSEIRNFI 
    ANSEMNQAST RMDKRPEIQD LDSNPPCPGS ASAKPEDVEE EEEEELEEED DDSLAGKSQE 
    DTVSPTPEPQ GVYEDEEDEE PPSLTMGFDH TRRCVEERGG GLLALEPTPT FGKGLDLRRA 
    AEEAFEVKDV LNSTLDSEVL KQTLYRQAKN QAYAMMLSLS EDTPLHAPSQ SSLDAWLNIT 
    GPSSESGAFN PINHL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.