Details for: C1QBP
Associated with
Other Information
Genular Protein ID: 2822119728
Symbol: C1QBP_HUMAN
Name: Complement component 1 Q subcomponent-binding protein, mitochondrial
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 8262387
Title: Cloning and expression of a cDNA covering the complete coding region of the P32 subunit of human pre-mRNA splicing factor SF2.
PubMed ID: 8262387
PubMed ID: 8195709
Title: Isolation, cDNA cloning, and overexpression of a 33-kD cell surface glycoprotein that binds to the globular 'heads' of C1q.
PubMed ID: 8195709
PubMed ID: 11278463
Title: The human gC1qR/p32 gene, C1qBP. Genomic organization and promoter analysis.
PubMed ID: 11278463
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 1830244
Title: Functional expression of cloned human splicing factor SF2: homology to RNA-binding proteins, U1 70K, and Drosophila splicing regulators.
PubMed ID: 1830244
PubMed ID: 8662673
Title: Isolation and characterization of the kininogen-binding protein p33 from endothelial cells. Identity with the gC1q receptor.
PubMed ID: 8662673
PubMed ID: 8567680
Title: Molecular cloning of human fibroblast hyaluronic acid-binding protein confirms its identity with P-32, a protein co-purified with splicing factor SF2. Hyaluronic acid-binding protein as P-32 protein, co-purified with splicing factor SF2.
PubMed ID: 8567680
PubMed ID: 8900153
Title: The binding protein for globular heads of complement C1q, gC1qR. Functional expression and characterization as a novel vitronectin binding factor.
PubMed ID: 8900153
PubMed ID: 8710908
Title: Identification of the zinc-dependent endothelial cell binding protein for high molecular weight kininogen and factor XII: identity with the receptor that binds to the globular 'heads' of C1q (gC1q-R).
PubMed ID: 8710908
PubMed ID: 9191880
Title: The C1q-binding cell membrane proteins cC1q-R and gC1q-R are released from activated cells: subcellular distribution and immunochemical characterization.
PubMed ID: 9191880
PubMed ID: 9299613
Title: P32/TAP, a cellular protein that interacts with EBNA-1 of Epstein-Barr virus.
PubMed ID: 9299613
PubMed ID: 9305894
Title: p32 protein, a splicing factor 2-associated protein, is localized in mitochondrial matrix and is functionally important in maintaining oxidative phosphorylation.
PubMed ID: 9305894
PubMed ID: 9233640
Title: Evidence that the two C1q binding membrane proteins, gC1q-R and cC1q-R, associate to form a complex.
PubMed ID: 9233640
PubMed ID: 9461517
Title: C1q-mediated chemotaxis by human neutrophils: involvement of gClqR and G-protein signalling mechanisms.
PubMed ID: 9461517
DOI: 10.1042/bj3300247
PubMed ID: 10479529
Title: Cytokeratin 1 and gC1qR mediate high molecular weight kininogen binding to endothelial cells.
PubMed ID: 10479529
PubMed ID: 10022843
Title: The splicing factor-associated protein, p32, regulates RNA splicing by inhibiting ASF/SF2 RNA binding and phosphorylation.
PubMed ID: 10022843
PubMed ID: 10747014
Title: gC1q-R/p32, a C1q-binding protein, is a receptor for the InlB invasion protein of Listeria monocytogenes.
PubMed ID: 10747014
PubMed ID: 10722602
Title: Staphylococcus aureus protein A recognizes platelet gC1qR/p33: a novel mechanism for staphylococcal interactions with platelets.
PubMed ID: 10722602
PubMed ID: 11086025
Title: Interaction between complement receptor gC1qR and hepatitis C virus core protein inhibits T-lymphocyte proliferation.
PubMed ID: 11086025
DOI: 10.1172/jci10323
PubMed ID: 10823864
Title: Rubella virus capsid associates with host cell protein p32 and localizes to mitochondria.
PubMed ID: 10823864
PubMed ID: 11493647
Title: Retargeting of the mitochondrial protein p32/gC1Qr to a cytoplasmic compartment and the cell surface.
PubMed ID: 11493647
PubMed ID: 12411480
Title: GW domains of the Listeria monocytogenes invasion protein InlB are SH3-like and mediate binding to host ligands.
PubMed ID: 12411480
DOI: 10.1093/emboj/cdf558
PubMed ID: 11859136
Title: Cooperation of C1q receptors and integrins in C1q-mediated endothelial cell adhesion and spreading.
PubMed ID: 11859136
PubMed ID: 12034482
Title: The N-terminal conserved domain of rubella virus capsid interacts with the C-terminal region of cellular p32 and overexpression of p32 enhances the viral infectivity.
PubMed ID: 12034482
PubMed ID: 12833064
Title: Human p32 protein relieves a post-transcriptional block to HIV replication in murine cells.
PubMed ID: 12833064
DOI: 10.1038/ncb1000
PubMed ID: 12574814
Title: Activation-dependent surface expression of gC1qR/p33 on human blood platelets.
PubMed ID: 12574814
DOI: 10.1267/THRO03020331
PubMed ID: 15031724
Title: Physical and functional interaction between BH3-only protein Hrk and mitochondrial pore-forming protein p32.
PubMed ID: 15031724
PubMed ID: 15243141
Title: Human p32, interacts with B subunit of the CCAAT-binding factor, CBF/NF-Y, and inhibits CBF-mediated transcription activation in vitro.
PubMed ID: 15243141
DOI: 10.1093/nar/gkh692
PubMed ID: 16177118
Title: gC1q receptor ligation selectively down-regulates human IL-12 production through activation of the phosphoinositide 3-kinase pathway.
PubMed ID: 16177118
PubMed ID: 16721827
Title: CDC2L5, a Cdk-like kinase with RS domain, interacts with the ASF/SF2-associated protein p32 and affects splicing in vivo.
PubMed ID: 16721827
DOI: 10.1002/jcb.20986
PubMed ID: 16537587
Title: Acetylated Tat regulates human immunodeficiency virus type 1 splicing through its interaction with the splicing regulator p32.
PubMed ID: 16537587
PubMed ID: 16140380
Title: Chemotaxis of human monocyte-derived dendritic cells to complement component C1q is mediated by the receptors gC1qR and cC1qR.
PubMed ID: 16140380
PubMed ID: 17881511
Title: HCV core protein interaction with gC1q receptor inhibits Th1 differentiation of CD4+ T cells via suppression of dendritic cell IL-12 production.
PubMed ID: 17881511
DOI: 10.1189/jlb.0507268
PubMed ID: 17693683
Title: Quantitative phosphoproteome profiling of Wnt3a-mediated signaling network: indicating the involvement of ribonucleoside-diphosphate reductase M2 subunit phosphorylation at residue serine 20 in canonical Wnt signal transduction.
PubMed ID: 17693683
PubMed ID: 17486078
Title: The autophagic inducer smARF interacts with and is stabilized by the mitochondrial p32 protein.
PubMed ID: 17486078
PubMed ID: 18191643
Title: Novel tyrosine phosphorylated and cardiolipin-binding protein CLPABP functions as mitochondrial RNA granule.
PubMed ID: 18191643
PubMed ID: 18676636
Title: Human p32 is a novel FOXC1-interacting protein that regulates FOXC1 transcriptional activity in ocular cells.
PubMed ID: 18676636
DOI: 10.1167/iovs.07-1625
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19004836
Title: Evidence for inhibitory interaction of hyaluronan-binding protein 1 (HABP1/p32/gC1qR) with Streptococcus pneumoniae hyaluronidase.
PubMed ID: 19004836
PubMed ID: 19164550
Title: Inhibition of RIG-I and MDA5-dependent antiviral response by gC1qR at mitochondria.
PubMed ID: 19164550
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 19608861
Title: Lysine acetylation targets protein complexes and co-regulates major cellular functions.
PubMed ID: 19608861
PubMed ID: 20810993
Title: An alternative role of C1q in cell migration and tissue remodeling: contribution to trophoblast invasion and placental development.
PubMed ID: 20810993
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 20950273
Title: Complement 1q-binding protein inhibits the mitochondrial permeability transition pore and protects against oxidative stress-induced death.
PubMed ID: 20950273
DOI: 10.1042/bj20101431
PubMed ID: 21536856
Title: Splicing factor 2-associated protein p32 participates in ribosome biogenesis by regulating the binding of Nop52 and fibrillarin to preribosome particles.
PubMed ID: 21536856
PubMed ID: 21544310
Title: Interaction of high-molecular-weight kininogen with endothelial cell binding proteins suPAR, gC1qR and cytokeratin 1 determined by surface plasmon resonance (BiaCore).
PubMed ID: 21544310
DOI: 10.1160/th10-09-0591
PubMed ID: 22700724
Title: DC-SIGN, C1q, and gC1qR form a trimolecular receptor complex on the surface of monocyte-derived immature dendritic cells.
PubMed ID: 22700724
PubMed ID: 22238231
Title: Binding of cellular p32 protein to the rubella virus P150 replicase protein via PxxPxR motifs.
PubMed ID: 22238231
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
PubMed ID: 32958672
Title: Unusually efficient CUG initiation of an overlapping reading frame in POLG mRNA yields novel protein POLGARF.
PubMed ID: 32958672
PubMed ID: 28942965
Title: Biallelic C1QBP mutations cause severe neonatal-, childhood-, or later-onset cardiomyopathy associated with combined respiratory-chain deficiencies.
PubMed ID: 28942965
PubMed ID: 10097078
Title: Crystal structure of human p32, a doughnut-shaped acidic mitochondrial matrix protein.
PubMed ID: 10097078
Sequence Information:
- Length: 282
- Mass: 31362
- Checksum: 2F747FA73BB1314B
- Sequence:
MLPLLRCVPR VLGSSVAGLR AAAPASPFRQ LLQPAPRLCT RPFGLLSVRA GSERRPGLLR PRGPCACGCG CGSLHTDGDK AFVDFLSDEI KEERKIQKHK TLPKMSGGWE LELNGTEAKL VRKVAGEKIT VTFNINNSIP PTFDGEEEPS QGQKVEEQEP ELTSTPNFVV EVIKNDDGKK ALVLDCHYPE DEVGQEDEAE SDIFSIREVS FQSTGESEWK DTNYTLNTDS LDWALYDHLM DFLADRGVDN TFADELVELS TALEHQEYIT FLEDLKSFVK SQ
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.