P2ry12 | ENSMUSG00000036353 | NCBI 70839

Details for: P2ry12

Gene ID: 70839

Symbol: P2ry12

Ensembl ID: ENSMUSG00000036353

Description: purinergic receptor P2Y, G-protein coupled 12

Associated with

Adp signalling through p2y purinoceptor 12
(R-MMU-392170)
Class a/1 (rhodopsin-like receptors)
(R-MMU-373076)
G alpha (i) signalling events
(R-MMU-418594)
Gpcr downstream signalling
(R-MMU-388396)
Gpcr ligand binding
(R-MMU-500792)
Hemostasis
(R-MMU-109582)
Nucleotide-like (purinergic) receptors
(R-MMU-418038)
P2y receptors
(R-MMU-417957)
Platelet activation, signaling and aggregation
(R-MMU-76002)
Signal amplification
(R-MMU-392518)
Signaling by gpcr
(R-MMU-372790)
Signal transduction
(R-MMU-162582)
Adenylate cyclase-inhibiting g protein-coupled receptor signaling pathway
(GO:0007193)
Adenylate cyclase-modulating g protein-coupled receptor signaling pathway
(GO:0007188)
Basal plasma membrane
(GO:0009925)
Calcium-mediated signaling
(GO:0019722)
Calcium ion transmembrane transport
(GO:0070588)
Caveola
(GO:0005901)
Cell body membrane
(GO:0044298)
Cell projection membrane
(GO:0031253)
Cell projection organization
(GO:0030030)
Cellular response to atp
(GO:0071318)
Cellular response to organic cyclic compound
(GO:0071407)
Cerebral cortex radial glia-guided migration
(GO:0021801)
Establishment of localization in cell
(GO:0051649)
External side of plasma membrane
(GO:0009897)
Glial cell migration
(GO:0008347)
G protein-coupled adenosine receptor activity
(GO:0001609)
G protein-coupled adenosine receptor signaling pathway
(GO:0001973)
G protein-coupled adp receptor activity
(GO:0001621)
G protein-coupled purinergic nucleotide receptor activity
(GO:0045028)
G protein-coupled purinergic nucleotide receptor signaling pathway
(GO:0035589)
G protein-coupled receptor signaling pathway
(GO:0007186)
Lamellipodium assembly
(GO:0030032)
Membrane
(GO:0016020)
Monoatomic ion transport
(GO:0006811)
Negative regulation of cell differentiation
(GO:0045596)
Negative regulation of norepinephrine secretion
(GO:0010700)
Phospholipase c-activating g protein-coupled receptor signaling pathway
(GO:0007200)
Plasma membrane
(GO:0005886)
Platelet activation
(GO:0030168)
Platelet aggregation
(GO:0070527)
Positive regulation of cell adhesion mediated by integrin
(GO:0033630)
Positive regulation of chemotaxis
(GO:0050921)
Positive regulation of integrin activation by cell surface receptor linked signal transduction
(GO:0033626)
Positive regulation of microglial cell migration
(GO:1904141)
Positive regulation of monoatomic ion transport
(GO:0043270)
Positive regulation of phosphatidylinositol 3-kinase/protein kinase b signal transduction
(GO:0051897)
Positive regulation of ruffle assembly
(GO:1900029)
Potassium ion transmembrane transport
(GO:0071805)
Regulation of calcium ion transport
(GO:0051924)
Regulation of chemotaxis
(GO:0050920)
Regulation of microglial cell migration
(GO:1904139)
Response to axon injury
(GO:0048678)
Substrate-dependent cell migration, cell extension
(GO:0006930)
Visual system development
(GO:0150063)

Other Information

Proteins

P2Y purinoceptor 12

Genular Protein ID: 1340554113

Symbol: P2Y12_MOUSE

Name: P2Y purinoceptor 12

UniProtKB Accession Codes:

Q9CPV9

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 12897207

Title: P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries.

PubMed ID: 12897207

DOI: 10.1172/jci17864

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

Sequence Information:

Length: 347
Mass: 39474
Checksum: F107488E57E025F1
Sequence:

MDVPGVNTTS ANTTFSPGTS TLCVRDYKIT QVLFPLLYTV LFFAGLITNS LAMRIFFQIR 
SKSNFIIFLK NTVISDLLMI LTFPFKILSD AKLGAGPLRT LVCQVTSVTF YFTMYISISF 
LGLITIDRYL KTTRPFKTSS PSNLLGAKIL SVVIWAFMFL ISLPNMILTN RRPKDKDVTK 
CSFLKSEFGL VWHEIVNYIC QVIFWINFLI VIVCYSLITK ELYRSYVRTR GSAKVPKKKV 
NVKVFIIIAV FFICFVPFHF ARIPYTLSQT RAVFDCSAEN TLFYVKESTL WLTSLNACLD 
PFIYFFLCKS FRNSLTSMLR CSNSTSTSGT NKKKGQEGGE PSEETPM

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: P2ry12

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries. PubMed ID: 12897207

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

Database document:

PubMed ID: 16141072

PubMed ID: 15489334

PubMed ID: 12897207

PubMed ID: 21183079