Details for: Rfx4

Gene ID: 71137

Symbol: Rfx4

Ensembl ID: ENSMUSG00000020037

Description: regulatory factor X, 4 (influences HLA class II expression)

Associated with

  • Cilium assembly
    (GO:0060271)
  • Dna-binding transcription activator activity, rna polymerase ii-specific
    (GO:0001228)
  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Negative regulation of smoothened signaling pathway
    (GO:0045879)
  • Nucleus
    (GO:0005634)
  • Positive regulation of transcription by rna polymerase ii
    (GO:0045944)
  • Protein binding
    (GO:0005515)
  • Regulation of protein processing
    (GO:0070613)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Rna polymerase ii cis-regulatory region sequence-specific dna binding
    (GO:0000978)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)
  • Telencephalon development
    (GO:0021537)

Other Information

Genular Protein ID: 1672598423

Symbol: RFX4_MOUSE

Name: Transcription factor RFX4

UniProtKB Accession Codes:

Q7TNK1 B2RS52 Q3V158 Q76KT2 Q8HWA6 Q9D453

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 CCDS 2 CTD 1 DNASU 1 EMBL 9 Ensembl 3 GO 10 Gene3D 1 GeneTree 1 HOGENOM 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 4 RNAct 1 RefSeq 2 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 1

Citations:

PubMed ID: 12925582

Title: Graded phenotypic response to partial and complete deficiency of a brain-specific transcript variant of the winged helix transcription factor RFX4.

PubMed ID: 12925582

DOI: 10.1242/dev.00661

PubMed ID: 14701801

Title: Restricted expression and photic induction of a novel mouse regulatory factor X4 transcript in the suprachiasmatic nucleus.

PubMed ID: 14701801

DOI: 10.1074/jbc.m312761200

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16893423

Title: Identification of potential target genes for RFX4_v3, a transcription factor critical for brain development.

PubMed ID: 16893423

DOI: 10.1111/j.1471-4159.2006.03930.x

PubMed ID: 18218630

Title: G-protein pathway suppressor 2 (GPS2) interacts with the regulatory factor X4 variant 3 (RFX4_v3) and functions as a transcriptional co-activator.

PubMed ID: 18218630

DOI: 10.1074/jbc.m708209200

Sequence Information:

  • Length: 735
  • Mass: 83371
  • Checksum: 5D51484CC26A8338
  • Sequence:
    • MHCGLLEEPD MDSTESWIER CLNESENKRY SSHTSLGNVS NDENEEKENN RASKPHSTPA 
TLQWLEENYE IAEGVCIPRS ALYMHYLDFC EKNDTQPVNA ASFGKIIRQQ FPQLTTRRLG 
TRGQSKYHYY GIAVKESSQY YDVMYSKKGA AWVSETGKRE VTKQTVAYSP RSKLGTLLPD 
FPNVKDLNLP ASLPEEKVST FIMMYRTHCQ RILDTVIRAN FDEVQSFLLH FWQGMPPHML 
PVLGSSTVVN IVGVCDSILY KAISGVLMPT VLQALPDSLT QVIRKFAKQL DEWLKVALHD 
LPENLRNIKF ELSRRFSQIL RRQTSLNHLC QASRTVIHSA DITFQMLEDW RNVDLSSITK 
QTLYTMEDSR DEHRRLIIQL YQEFDHLLEE QSPIESYIEW LDTMVDRCVV KVAAKRQGSL 
KKVAQQFLLM WSCFGTRVIR DMTLHSAPSF GSFHLIHLMF DDYVLYLLES LHCQERANEL 
MRAMKGEGST AEAQEEIILT EATPPTPSPG PSFSPAKSAT SVEVPPPSSP VSNPSPEYTG 
LSTAGAMQSY TWSLTYTVTT AAGSPAENSQ QLPCMRSTHM PSSSVTHRIP VYSHREEHGY 
TGSYNYGSYG NQHPHPLQNQ YPALPHDTAI SGPLHYSPYH RSSAQYPFNS PTSRMEPCLM 
SSTPRLHPTP VTPRWPEVPT ANACYTSPSV HSTRYGNSSD MYTPLTTRRN SEYEHMQHFP 
GFAYINGEAS TGWAK

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.