C1QB | ENSG00000173369 | NCBI 713

Details for: C1QB

Gene ID: 713

Symbol: C1QB

Ensembl ID: ENSG00000173369

Description: complement C1q B chain

Associated with

Classical antibody-mediated complement activation
(R-HSA-173623)
Complement cascade
(R-HSA-166658)
Creation of c4 and c2 activators
(R-HSA-166786)
Immune system
(R-HSA-168256)
Initial triggering of complement
(R-HSA-166663)
Innate immune system
(R-HSA-168249)
Regulation of complement cascade
(R-HSA-977606)
Blood microparticle
(GO:0072562)
Collagen-containing extracellular matrix
(GO:0062023)
Collagen trimer
(GO:0005581)
Complement activation
(GO:0006956)
Complement activation, classical pathway
(GO:0006958)
Complement component c1 complex
(GO:0005602)
Complement component c1q complex
(GO:0062167)
Extracellular region
(GO:0005576)
Innate immune response
(GO:0045087)
Postsynapse
(GO:0098794)
Protein binding
(GO:0005515)
Synapse
(GO:0045202)
Synapse pruning
(GO:0098883)

Other Information

Proteins

Complement C1q subcomponent subunit B

Genular Protein ID: 1102049999

Symbol: C1QB_HUMAN

Name: Complement C1q subcomponent subunit B

UniProtKB Accession Codes:

P02746 Q5T959 Q96H17

Database IDs:

Citations:

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3000358

Title: Molecular cloning and characterization of the complementary DNA and gene coding for the B-chain of subcomponent C1q of the human complement system.

PubMed ID: 3000358

DOI: 10.1042/bj2310729

PubMed ID: 708376

Title: Amino acid sequence of the N-terminal 108 amino acid residues of the B chain of subcomponent C1q of the first component of human complement.

PubMed ID: 708376

DOI: 10.1042/bj1730863

PubMed ID: 486087

Title: Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement.

PubMed ID: 486087

DOI: 10.1042/bj1790367

PubMed ID: 6981411

Title: Completion of the amino acid sequences of the A and B chains of subcomponent C1q of the first component of human complement.

PubMed ID: 6981411

DOI: 10.1042/bj2030559

PubMed ID: 6208566

Title: Cloning and characterization of the complementary DNA for the B chain of normal human serum C1q.

PubMed ID: 6208566

DOI: 10.1098/rstb.1984.0095

PubMed ID: 12847249

Title: Modular organization of the carboxyl-terminal, globular head region of human C1q A, B, and C chains.

PubMed ID: 12847249

DOI: 10.4049/jimmunol.171.2.812

PubMed ID: 19006321

Title: Interaction of human C1q with IgG and IgM: revisited.

PubMed ID: 19006321

DOI: 10.1021/bi801131h

PubMed ID: 6286235

Title: Comparable content of hydroxylysine-linked glycosides in subcomponents C1q of the first component of human, bovine and mouse complement.

PubMed ID: 6286235

DOI: 10.1016/s0174-173x(81)80015-5

PubMed ID: 12960167

Title: The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties.

PubMed ID: 12960167

DOI: 10.1074/jbc.m307764200

PubMed ID: 9777412

Title: Molecular basis of hereditary C1q deficiency.

PubMed ID: 9777412

DOI: 10.1016/s0171-2985(98)80033-8

PubMed ID: 9476130

Title: Molecular basis of a new type of C1q-deficiency associated with a non-functional low molecular weight (LMW) C1q: parallels and differences to other known genetic C1q-defects.

PubMed ID: 9476130

DOI: 10.1016/s0162-3109(97)00065-9

PubMed ID: 16959974

Title: The consensus coding sequences of human breast and colorectal cancers.

PubMed ID: 16959974

DOI: 10.1126/science.1133427

Sequence Information:

Length: 253
Mass: 26722
Checksum: D80C753C0D430EDC
Sequence:

MMMKIPWGSI PVLMLLLLLG LIDISQAQLS CTGPPAIPGI PGIPGTPGPD GQPGTPGIKG 
EKGLPGLAGD HGEFGEKGDP GIPGNPGKVG PKGPMGPKGG PGAPGAPGPK GESGDYKATQ 
KIAFSATRTI NVPLRRDQTI RFDHVITNMN NNYEPRSGKF TCKVPGLYYF TYHASSRGNL 
CVNLMRGRER AQKVVTFCDY AYNTFQVTTG GMVLKLEQGE NVFLQATDKN SLLGMEGANS 
IFSGFLLFPD MEA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: C1QB

Associated with

Other Information

The DNA sequence and biological annotation of human chromosome 1. PubMed ID: 16710414

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

Molecular cloning and characterization of the complementary DNA and gene coding for the B-chain of subcomponent C1q of the human complement system. PubMed ID: 3000358

Amino acid sequence of the N-terminal 108 amino acid residues of the B chain of subcomponent C1q of the first component of human complement. PubMed ID: 708376

Complete amino acid sequences of the three collagen-like regions present in subcomponent C1q of the first component of human complement. PubMed ID: 486087

Completion of the amino acid sequences of the A and B chains of subcomponent C1q of the first component of human complement. PubMed ID: 6981411

Cloning and characterization of the complementary DNA for the B chain of normal human serum C1q. PubMed ID: 6208566

Modular organization of the carboxyl-terminal, globular head region of human C1q A, B, and C chains. PubMed ID: 12847249

Interaction of human C1q with IgG and IgM: revisited. PubMed ID: 19006321

Comparable content of hydroxylysine-linked glycosides in subcomponents C1q of the first component of human, bovine and mouse complement. PubMed ID: 6286235

The crystal structure of the globular head of complement protein C1q provides a basis for its versatile recognition properties. PubMed ID: 12960167

Molecular basis of hereditary C1q deficiency. PubMed ID: 9777412

Molecular basis of a new type of C1q-deficiency associated with a non-functional low molecular weight (LMW) C1q: parallels and differences to other known genetic C1q-defects. PubMed ID: 9476130

The consensus coding sequences of human breast and colorectal cancers. PubMed ID: 16959974