Details for: Isx

Gene ID: 71597

Symbol: Isx

Ensembl ID: ENSMUSG00000031621

Description: intestine specific homeobox

Associated with

  • Dna-binding transcription factor activity, rna polymerase ii-specific
    (GO:0000981)
  • Dna-binding transcription repressor activity, rna polymerase ii-specific
    (GO:0001227)
  • Negative regulation of intestinal absorption
    (GO:1904479)
  • Negative regulation of transcription by rna polymerase ii
    (GO:0000122)
  • Nucleus
    (GO:0005634)
  • Regulation of transcription by rna polymerase ii
    (GO:0006357)
  • Regulation of vitamin a metabolic process
    (GO:1901738)
  • Rna polymerase ii transcription regulatory region sequence-specific dna binding
    (GO:0000977)
  • Sequence-specific dna binding
    (GO:0043565)
  • Sequence-specific double-stranded dna binding
    (GO:1990837)

Other Information

Genular Protein ID: 3714633928

Symbol: ISX_MOUSE

Name: Intestine-specific homeobox

UniProtKB Accession Codes:

A1A546 A1A545 Q9D2Z0

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID-ORCS 1 CCDS 2 CDD 1 CTD 1 EMBL 3 Ensembl 2 ExpressionAtlas 1 GO 8 Gene3D 1 GeneTree 1 HOGENOM 1 InParanoid 1 InterPro 4 KEGG 1 MGI 1 NCBI Taxonomy 1 OMA 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PaxDb 1 Pfam 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 RNAct 1 RefSeq 2 SMART 1 SMR 1 STRING 1 SUPFAM 1 TreeFam 1 UCSC 2 VEuPathDB 1 eggNOG 1 iPTMnet 1

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 16971476

Title: A dynamic expression survey identifies transcription factors relevant in mouse digestive tract development.

PubMed ID: 16971476

DOI: 10.1242/dev.02537

PubMed ID: 18093975

Title: Isx participates in the maintenance of vitamin A metabolism by regulation of beta-carotene 15,15'-monooxygenase (Bcmo1) expression.

PubMed ID: 18093975

DOI: 10.1074/jbc.m707928200

Sequence Information:

  • Length: 240
  • Mass: 27169
  • Checksum: C7BFA37A5950FA1B
  • Sequence:
    • MAGPTIHRDM EKSSGYCEAP ENLGLSFSIE AILKKPTERR SLPRPQSICK EDSRQTTIPG 
SKLERPPQDQ PQEEKKNKRR VRTTFTTEQL QELEKLFHFT HYPDIHVRSQ LASRINLPEA 
RVQIWFQNQR AKWRKQEKSG NLSAPQQPGE AGLALPSNMD VSGPVLTPTA MTTLVPPTEC 
CLLSQTQLPS SWFPTQIPLV PWHPWDLQPL PGPLTQHPCV PTFMFPPLHP KWGSICATST

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.