Tradd | ENSMUSG00000031887 | NCBI 71609

Details for: Tradd

Gene ID: 71609

Symbol: Tradd

Ensembl ID: ENSMUSG00000031887

Description: TNFRSF1A-associated via death domain

Associated with

Apoptosis
(R-MMU-109581)
Casp8 activity is inhibited
(R-MMU-5218900)
Caspase activation via death receptors in the presence of ligand
(R-MMU-140534)
Caspase activation via extrinsic apoptotic signalling pathway
(R-MMU-5357769)
Death receptor signaling
(R-MMU-73887)
Dimerization of procaspase-8
(R-MMU-69416)
Programmed cell death
(R-MMU-5357801)
Regulated necrosis
(R-MMU-5218859)
Regulation by c-flip
(R-MMU-3371378)
Regulation of necroptotic cell death
(R-MMU-5675482)
Regulation of tnfr1 signaling
(R-MMU-5357905)
Ripk1-mediated regulated necrosis
(R-MMU-5213460)
Signal transduction
(R-MMU-162582)
Tnfr1-induced nf-kappa-b signaling pathway
(R-MMU-5357956)
Tnfr1-induced proapoptotic signaling
(R-MMU-5357786)
Tnf signaling
(R-MMU-75893)
Apoptotic process
(GO:0006915)
Canonical nf-kappab signal transduction
(GO:0007249)
Cell surface receptor protein tyrosine kinase signaling pathway
(GO:0007169)
Cellular response to tumor necrosis factor
(GO:0071356)
Cytoplasm
(GO:0005737)
Cytoskeleton
(GO:0005856)
Death domain binding
(GO:0070513)
Extrinsic apoptotic signaling pathway
(GO:0097191)
Extrinsic apoptotic signaling pathway via death domain receptors
(GO:0008625)
Identical protein binding
(GO:0042802)
Kinase binding
(GO:0019900)
Molecular adaptor activity
(GO:0060090)
Nucleus
(GO:0005634)
Plasma membrane
(GO:0005886)
Positive regulation of canonical nf-kappab signal transduction
(GO:0043123)
Positive regulation of cell migration
(GO:0030335)
Positive regulation of execution phase of apoptosis
(GO:1900119)
Positive regulation of hair follicle development
(GO:0051798)
Positive regulation of inflammatory response
(GO:0050729)
Positive regulation of interferon-beta production
(GO:0032728)
Protein-containing complex
(GO:0032991)
Protein-containing complex binding
(GO:0044877)
Protein binding
(GO:0005515)
Receptor complex
(GO:0043235)
Regulation of apoptotic process
(GO:0042981)
Signaling adaptor activity
(GO:0035591)
Trail-activated apoptotic signaling pathway
(GO:0036462)
Transmembrane receptor protein tyrosine kinase adaptor activity
(GO:0005068)
Tumor necrosis factor-mediated signaling pathway
(GO:0033209)
Tumor necrosis factor receptor binding
(GO:0005164)
Tumor necrosis factor receptor superfamily complex
(GO:0002947)

Other Information

Proteins

TRADD_MOUSE

Genular Protein ID: 3186914678

Symbol: TRADD_MOUSE

Name: N/A

UniProtKB Accession Codes:

Q3U0V2

Database IDs:

Citations:

PubMed ID: 16141072

Title: The transcriptional landscape of the mammalian genome.

PubMed ID: 16141072

DOI: 10.1126/science.1112014

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14585990

Title: TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB.

PubMed ID: 14585990

DOI: 10.1128/mcb.23.22.8334-8344.2003

PubMed ID: 16702408

Title: Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion.

PubMed ID: 16702408

DOI: 10.1101/gad.1387406

PubMed ID: 21183079

Title: A tissue-specific atlas of mouse protein phosphorylation and expression.

PubMed ID: 21183079

DOI: 10.1016/j.cell.2010.12.001

PubMed ID: 22561347

Title: TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation.

PubMed ID: 22561347

DOI: 10.1038/ncb2496

PubMed ID: 30185824

Title: RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development.

PubMed ID: 30185824

DOI: 10.1038/s41418-018-0166-8

PubMed ID: 30902834

Title: Salmonella effectors SseK1 and SseK3 target death domain proteins in the TNF and TRAIL signaling pathways.

PubMed ID: 30902834

DOI: 10.1074/mcp.ra118.001093

Sequence Information:

Length: 310
Mass: 34577
Checksum: 225F00D4022691BB
Sequence:

MAAGQNGHEE WVGSAYLFLE SAVDKVILSE AYTDPKKKVA IYKALQTALS ESGDSSDVLQ 
ILKIHCSDPQ LIVQLRFCGR VLCGRFLQAY REGALRTALQ RCMAPALAQE ALRLQLELRA 
GAEQLDSWLT DEERCLNYIL AQKPDRLRDE ELAELEDELC KLTCDCTGQG GAIQVASAGS 
KFPVSSPTEE KPLPAACQTF LFHGQLVVNR PLTLQDQQTF ARSVGLKWRR VGRSLQRNCR 
ALRDPALDSL AYEYERDGLY EQAFQLLRRF MQAEGRRATL QRLVEALEEN ELTSLAEDLL 
GQAEPDGGLA

The gene details are incomplete or unavailable at the moment.

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.

Details for: Tradd

Associated with

Other Information

The transcriptional landscape of the mammalian genome. PubMed ID: 16141072

The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC). PubMed ID: 15489334

TRUSS, a novel tumor necrosis factor receptor 1 scaffolding protein that mediates activation of the transcription factor NF-kappaB. PubMed ID: 14585990

Keratin 17 modulates hair follicle cycling in a TNFalpha-dependent fashion. PubMed ID: 16702408

A tissue-specific atlas of mouse protein phosphorylation and expression. PubMed ID: 21183079

TRADD contributes to tumour suppression by regulating ULF-dependent p19Arf ubiquitylation. PubMed ID: 22561347

RIPK1 prevents TRADD-driven, but TNFR1 independent, apoptosis during development. PubMed ID: 30185824

Salmonella effectors SseK1 and SseK3 target death domain proteins in the TNF and TRAIL signaling pathways. PubMed ID: 30902834