Details for: C2

Gene ID: 717

Symbol: C2

Ensembl ID: ENSG00000166278

Description: complement C2

Associated with

Other Information

Genular Protein ID: 329913789

Symbol: CO2_HUMAN

Name: Complement C2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2949737

Title: Primary structure of human complement component C2. Homology to two unrelated protein families.

PubMed ID: 2949737

DOI: 10.1042/bj2390339

PubMed ID: 2493504

Title: cDNA cloning and expression of human complement component C2.

PubMed ID: 2493504

PubMed ID: 8326124

Title: Structure of the human C2 gene.

PubMed ID: 8326124

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6922702

Title: The purification and properties of the second component of guinea-pig complement.

PubMed ID: 6922702

DOI: 10.1042/bj2050059

PubMed ID: 2997031

Title: DNA polymorphism of the C2 locus.

PubMed ID: 2997031

DOI: 10.1007/bf00430921

PubMed ID: 10734221

Title: A Schistosoma protein, Sh-TOR, is a novel inhibitor of complement which binds human C2.

PubMed ID: 10734221

DOI: 10.1016/s0014-5793(00)01304-1

PubMed ID: 6149575

Title: Structure and activation of complement components C2 and factor B.

PubMed ID: 6149575

DOI: 10.1098/rstb.1984.0091

PubMed ID: 6555044

Title: The reaction of iodine and thiol-blocking reagents with human complement components C2 and factor B. Purification and N-terminal amino acid sequence of a peptide from C2a containing a free thiol group.

PubMed ID: 6555044

DOI: 10.1042/bj2130201

PubMed ID: 6199794

Title: Isolation of cDNA clones for human complement component C2.

PubMed ID: 6199794

DOI: 10.1073/pnas.81.4.1212

PubMed ID: 3643061

Title: Cell-specific expression of the human complement protein factor B gene: evidence for the role of two distinct 5'-flanking elements.

PubMed ID: 3643061

DOI: 10.1016/0092-8674(87)90436-3

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17027507

Title: Structure of complement component C2A: implications for convertase formation and substrate binding.

PubMed ID: 17027507

DOI: 10.1016/j.str.2006.08.008

PubMed ID: 19237749

Title: The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation.

PubMed ID: 19237749

DOI: 10.1107/s0907444909000389

PubMed ID: 8621452

Title: Type II human complement C2 deficiency. Allele-specific amino acid substitutions (Ser189 --> Phe; Gly444 --> Arg) cause impaired C2 secretion.

PubMed ID: 8621452

DOI: 10.1074/jbc.271.10.5824

PubMed ID: 9670930

Title: A novel type II complement C2 deficiency allele in an African-American family.

PubMed ID: 9670930

PubMed ID: 16518403

Title: Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration.

PubMed ID: 16518403

DOI: 10.1038/ng1750

Sequence Information:

  • Length: 752
  • Mass: 83268
  • Checksum: 5A96A13E700CF444
  • Sequence:
  • MGPLMVLFCL LFLYPGLADS APSCPQNVNI SGGTFTLSHG WAPGSLLTYS CPQGLYPSPA 
    SRLCKSSGQW QTPGATRSLS KAVCKPVRCP APVSFENGIY TPRLGSYPVG GNVSFECEDG 
    FILRGSPVRQ CRPNGMWDGE TAVCDNGAGH CPNPGISLGA VRTGFRFGHG DKVRYRCSSN 
    LVLTGSSERE CQGNGVWSGT EPICRQPYSY DFPEDVAPAL GTSFSHMLGA TNPTQKTKES 
    LGRKIQIQRS GHLNLYLLLD CSQSVSENDF LIFKESASLM VDRIFSFEIN VSVAIITFAS 
    EPKVLMSVLN DNSRDMTEVI SSLENANYKD HENGTGTNTY AALNSVYLMM NNQMRLLGME 
    TMAWQEIRHA IILLTDGKSN MGGSPKTAVD HIREILNINQ KRNDYLDIYA IGVGKLDVDW 
    RELNELGSKK DGERHAFILQ DTKALHQVFE HMLDVSKLTD TICGVGNMSA NASDQERTPW 
    HVTIKPKSQE TCRGALISDQ WVLTAAHCFR DGNDHSLWRV NVGDPKSQWG KEFLIEKAVI 
    SPGFDVFAKK NQGILEFYGD DIALLKLAQK VKMSTHARPI CLPCTMEANL ALRRPQGSTC 
    RDHENELLNK QSVPAHFVAL NGSKLNINLK MGVEWTSCAE VVSQEKTMFP NLTDVREVVT 
    DQFLCSGTQE DESPCKGESG GAVFLERRFR FFQVGLVSWG LYNPCLGSAD KNSRKRAPRS 
    KVPPPRDFHI NLFRMQPWLR QHLGDVLNFL PL

Genular Protein ID: 2021909498

Symbol: B4DQI1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 506
  • Mass: 56466
  • Checksum: 3069E8D3AF10CC4D
  • Sequence:
  • MGTRSAIAAP RILCSRGLRS GSARATGSGV ERSPSAAIFS FEINVSVAII TFASEPKVLM 
    SVLNDNSRDM TEVISSLENA NYKDHENGTG TNTYAALNSV YLMMNNQMRL LGMETMAWQE 
    IRHAIILLTD GKSNMGGSPK TAVDHIREIL NINQKRNDYL DIYAIGVGKL DVDWRELNEL 
    GSKKDGERHA FILQDTKALH QVFEHMLDVS KLTDTICGVG NMSANASDQE RTPWHVTIKP 
    KSQETCRGAL ISDQWVLTAA HCFRDGNDHS LWRVNVGDPK SQWGKEFLIE KAVISPGFDV 
    FAKKNQGILE FYGDDIALLK LAQKVKMSTH ARPICLPCTM EANLALRRPQ GSTCRDHENE 
    LLNKQSVPAH FVALNGSKLN INLKMGVEWT SCAEVVSQEK TMFPNLTDVR EVVTDQFLCS 
    GTQEDESPCK GESGGAVFLE RRFRFFQVGL VSWGLYNPCL GSADKNSRKR APRSKVPPPR 
    DFHINLFRMQ PWLRQHLGDV LNFLPL

Genular Protein ID: 1968148032

Symbol: Q8N6L6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

Sequence Information:

  • Length: 328
  • Mass: 35451
  • Checksum: 3EE77FE0818959C5
  • Sequence:
  • MGPLMVLFCL LFLYPGLADS APSCPQNVNI SGGTFTLSHG WAPGSLLTYS CPQGLYPSPA 
    SRLCKSSGQW QTPGATRSLS KAVCKPVRCP APVSFENGIY TPRLGSYPVG GNVSFECEDG 
    FILRGSPVRQ CRPNGMWDGE TAVCDNGAGH CPNPGISLGA VRTGFRFGHG DKVRYRCSSN 
    LVLTGSSERE CQGNGVWSGT EPICRQPYSY DFPEDVAPAL GTSFSHMLGA TNPTQKTKES 
    LGRKIQIQRS GHLNLYLLLD CSQSVSENDF LIFKESASLM VDRVRNQESA CSRGLPVLTI 
    SLCLLPLLRT PLTAHLLQEV FSDYTHAM

Genular Protein ID: 1536608682

Symbol: B4DV48_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 723
  • Mass: 80106
  • Checksum: B8D36BDA8762DDD6
  • Sequence:
  • MAGLLGAFSP TPAPRACTHP QHHGCARAAD SGRPQEPPGL CLRRSANVRL PAGFAQAVRC 
    PAPVSFENGI YTPRLGSYPV GGNVSFECED GFILRGSPVR QCRPNGMWDG ETAVCDNGAG 
    HCPNPGISLG AVRTGFRFGH GDKVRYRCSS NLVLTGSSER ECQGNGVWSG TEPICRQPYS 
    YDFPEDVAPA LGTSFSHMLG ATNPTQKTKE SLGRKIQIQR SGHLNLYLLL DCSQSVSEND 
    FLIFKESASP MVDRIFSFEI NVSVAIITFA SEPKVLMSVL NDNSRDMTEV ISSLENANYK 
    DHENGTGTNT YAALNSVYLM MNNQMRLLGM ETMAWQEIRH AIILLTDGKS NMGGSPKTAV 
    DHIREILNIN QKRNDYLDIY AIGVGKLDVD WRELNELGSK KDGERHAFIL QDTKALHQVF 
    EHMLDVSKLT DTICGVGNMS ANASDQERTP WHVTIKPKSQ ETCRGALISD QWVLTAAHCF 
    RDGNDHSLWR VNVGDPKSQW GKEFLIEKAV ISPGFDVFAK KNQGILEFYG DDIALLKLAQ 
    KVKMSTHARP ICLPCTMEAN LALRRPQGST CRDHENELLN KQSVPAHFVA LNGSKLNINL 
    KMGVEWTSCA EVVSQEKTMF PNLTDVREVV TDQFLCSGTQ EDESPCKGES GGAVFLERRF 
    RFFQVGLVSW GLYNPCLGSA DKNSRKRAPR SKVPPPRDFH INLFRMQPWL RQHLGDVLNF 
    LPL

Genular Protein ID: 243375752

Symbol: A0A0G2JL69_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 723
  • Mass: 80150
  • Checksum: 40EB07EA5B050DD5
  • Sequence:
  • MAGLLGAFSP TPAPRACTHP QHHGCARAAD SGRPQEPPGL CLRRSANVRL PVGFAQAVRC 
    PAPVSFENGI YTPRLGSYPV GGNVSFECED GFILRGSPVR QCRPNGMWDG ETAVCDNGAG 
    HCPNPGISLG AVRTGFRFGH GDKVRYRCSS NLVLTGSSER ECQGNGVWSG TEPICRQPYS 
    YDFPEDVAPA LGTSFSHMLG ATNPTQKTKE SLGRKIQIQR SGHLNLYLLL DCSQSVSEND 
    FLIFKESASL MVDRIFSFEI NVSVAIITFA SEPKVLMSVL NDNSRDMTEV ISSLENANYK 
    DHENGTGTNT YAALNSVYLM MNNQMRLLGM ETMAWQEIRH AIILLTDGKS NMGGSPKTAV 
    DHIREILNIN QKRNDYLDIY AIGVGKLDVD WRELNELGSK KDGERHAFIL QDTKALHQVF 
    EHMLDVSKLT DTICGVGNMS ANASDQERTP WHVTIKPKSQ ETCRGALISD QWVLTAAHCF 
    RDGNDHSLWR VNVGDPKSQW GKEFLIEKAV ISPGFDVFAK KNQGILEFYG DDIALLKLAQ 
    KVKMSTHARP ICLPCTMEAN LALRRPQGST CRDHENELLN KQSVPAHFVA LNGSKLNINL 
    KMGVEWTSCA EVVSQEKTMF PNLTDVREVV TDQFLCSGTQ EDESPCKGES GGAVFLERRF 
    RFFQVGLVSW GLYNPCLGSA DKNSRKRAPR SKVPPPRDFH INLFRMQPWL RQHLGDVLNF 
    LPL

Genular Protein ID: 2492507287

Symbol: Q53HP3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 752
  • Mass: 83284
  • Checksum: B9AF4D3E700CF443
  • Sequence:
  • MGPLMVLFCL LFLYPGLADS APSCPQNVNI SGGTFTLSHG WAPGSLLTYS CPQGLYPSPA 
    SRLCKSSGQW QTPGATRSLS KAVCKPVRCP APVSFENGIY TPRLGSYPVG GNVSFECEDG 
    FILRGSPVRQ CRPNGMWDGE TAVCDNGAGH CPNPGISLGA VRTGFRFGHG DKVRYRCSSN 
    LVLTGSSERE CQGNGVWSGT EPICRQPYSY DFPEDVAPAL GTSFSHMLGA TNLTQKTKES 
    LGRKIQIQRS GHLNLYLLLD CSQSVSENDF LIFKESASLM VDRIFSFEIN VSVAIITFAS 
    EPKVLMSVLN DNSRDMTEVI SSLENANYKD HENGTGTNTY AALNSVYLMM NNQMRLLGME 
    TMAWQEIRHA IILLTDGKSN MGGSPKTAVD HIREILNINQ KRNDYLDIYA IGVGKLDVDW 
    RELNELGSKK DGERHAFILQ DTKALHQVFE HMLDVSKLTD TICGVGNMSA NASDQERTPW 
    HVTIKPKSQE TCRGALISDQ WVLTAAHCFR DGNDHSLWRV NVGDPKSQWG KEFLIEKAVI 
    SPGFDVFAKK NQGILEFYGD DIALLKLAQK VKMSTHARPI CLPCTMEANL ALRRPQGSTC 
    RDHENELLNK QSVPAHFVAL NGSKLNINLK MGVEWTSCAE VVSQEKTMFP NLTDVREVVT 
    DQFLCSGTQE DESPCKGESG GAVFLERRFR FFQVGLVSWG LYNPCLGSAD KNSRKRAPRS 
    KVPPPRDFHI NLFRMQPWLR QHLGDVLNFL PL

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.