Details for: C2

Gene ID: 717

Symbol: C2

Ensembl ID: ENSG00000166278

Description: complement C2

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: polychromatophilic erythroblast (CL0000550)
    Fold Change: 83.8663
    Cell Significance Index: -13.0500
  • Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
    Fold Change: 51.6473
    Cell Significance Index: -13.1000
  • Cell Name: smooth muscle fiber of ileum (CL1000278)
    Fold Change: 32.8305
    Cell Significance Index: -15.5000
  • Cell Name: ileal goblet cell (CL1000326)
    Fold Change: 23.2034
    Cell Significance Index: -15.5700
  • Cell Name: orthochromatic erythroblast (CL0000552)
    Fold Change: 10.6066
    Cell Significance Index: -13.0800
  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 3.5672
    Cell Significance Index: 9.4100
  • Cell Name: stromal cell of bone marrow (CL0010001)
    Fold Change: 3.3071
    Cell Significance Index: -13.0500
  • Cell Name: tuft cell of colon (CL0009041)
    Fold Change: 1.1778
    Cell Significance Index: 1063.4600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 1.0960
    Cell Significance Index: 65.8000
  • Cell Name: intestinal crypt stem cell of colon (CL0009043)
    Fold Change: 0.9915
    Cell Significance Index: 107.8500
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.7837
    Cell Significance Index: 127.4600
  • Cell Name: neutrophil progenitor cell (CL0000834)
    Fold Change: 0.7580
    Cell Significance Index: 20.2800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.7249
    Cell Significance Index: 10.7000
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.4573
    Cell Significance Index: 91.7400
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 0.4301
    Cell Significance Index: 85.3600
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.3986
    Cell Significance Index: 142.9900
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: 0.3366
    Cell Significance Index: 6.5700
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: 0.2142
    Cell Significance Index: 8.1100
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: 0.1953
    Cell Significance Index: 9.8700
  • Cell Name: colon goblet cell (CL0009039)
    Fold Change: 0.1748
    Cell Significance Index: 17.2900
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: 0.1702
    Cell Significance Index: 128.8200
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: 0.1698
    Cell Significance Index: 7.5100
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: 0.1585
    Cell Significance Index: 23.0400
  • Cell Name: fallopian tube secretory epithelial cell (CL4030006)
    Fold Change: 0.1299
    Cell Significance Index: 2.0100
  • Cell Name: enteroendocrine cell of small intestine (CL0009006)
    Fold Change: 0.1096
    Cell Significance Index: 2.7400
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0847
    Cell Significance Index: 159.4700
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: 0.0842
    Cell Significance Index: 11.5600
  • Cell Name: enteroendocrine cell of colon (CL0009042)
    Fold Change: 0.0785
    Cell Significance Index: 14.9400
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: 0.0501
    Cell Significance Index: 1.4000
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: 0.0387
    Cell Significance Index: 59.5900
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: 0.0255
    Cell Significance Index: 16.2000
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: 0.0241
    Cell Significance Index: 44.3700
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.0078
    Cell Significance Index: 0.1700
  • Cell Name: GABAergic interneuron (CL0011005)
    Fold Change: 0.0032
    Cell Significance Index: 2.1900
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: 0.0005
    Cell Significance Index: 0.6500
  • Cell Name: Hofbauer cell (CL3000001)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0124
    Cell Significance Index: -2.2300
  • Cell Name: small intestine goblet cell (CL1000495)
    Fold Change: -0.0125
    Cell Significance Index: -0.4400
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: -0.0136
    Cell Significance Index: -7.4200
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0140
    Cell Significance Index: -10.4000
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0152
    Cell Significance Index: -1.8700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: -0.0154
    Cell Significance Index: -0.3300
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0182
    Cell Significance Index: -8.2400
  • Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
    Fold Change: -0.0200
    Cell Significance Index: -14.6400
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0210
    Cell Significance Index: -11.8700
  • Cell Name: hair follicular keratinocyte (CL2000092)
    Fold Change: -0.0224
    Cell Significance Index: -9.9000
  • Cell Name: odontoblast (CL0000060)
    Fold Change: -0.0228
    Cell Significance Index: -2.9200
  • Cell Name: enterocyte of epithelium of large intestine (CL0002071)
    Fold Change: -0.0254
    Cell Significance Index: -1.1500
  • Cell Name: epithelial cell of stomach (CL0002178)
    Fold Change: -0.0408
    Cell Significance Index: -4.7600
  • Cell Name: leptomeningeal cell (CL0000708)
    Fold Change: -0.0470
    Cell Significance Index: -1.0100
  • Cell Name: abnormal cell (CL0001061)
    Fold Change: -0.0559
    Cell Significance Index: -5.7100
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: -0.0612
    Cell Significance Index: -1.9600
  • Cell Name: bladder urothelial cell (CL1001428)
    Fold Change: -0.0668
    Cell Significance Index: -3.4700
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0743
    Cell Significance Index: -15.6400
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0760
    Cell Significance Index: -12.9800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0824
    Cell Significance Index: -6.3200
  • Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
    Fold Change: -0.0949
    Cell Significance Index: -9.8900
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: -0.0974
    Cell Significance Index: -1.6700
  • Cell Name: placental villous trophoblast (CL2000060)
    Fold Change: -0.0985
    Cell Significance Index: -2.6300
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.1097
    Cell Significance Index: -14.1700
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.1150
    Cell Significance Index: -13.1700
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.1162
    Cell Significance Index: -6.5200
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: -0.1177
    Cell Significance Index: -1.9800
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: -0.1334
    Cell Significance Index: -1.9100
  • Cell Name: tonsil germinal center B cell (CL2000006)
    Fold Change: -0.1338
    Cell Significance Index: -15.7800
  • Cell Name: intestinal tuft cell (CL0019032)
    Fold Change: -0.1346
    Cell Significance Index: -8.2500
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: -0.1486
    Cell Significance Index: -2.2400
  • Cell Name: sebum secreting cell (CL0000317)
    Fold Change: -0.1609
    Cell Significance Index: -11.3800
  • Cell Name: glycinergic neuron (CL1001509)
    Fold Change: -0.1716
    Cell Significance Index: -9.0100
  • Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
    Fold Change: -0.1843
    Cell Significance Index: -14.6000
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.1864
    Cell Significance Index: -8.7600
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: -0.1974
    Cell Significance Index: -14.7100
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.2016
    Cell Significance Index: -5.7800
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.2209
    Cell Significance Index: -10.3000
  • Cell Name: eye photoreceptor cell (CL0000287)
    Fold Change: -0.2267
    Cell Significance Index: -14.2900
  • Cell Name: keratocyte (CL0002363)
    Fold Change: -0.2288
    Cell Significance Index: -3.6300
  • Cell Name: early pro-B cell (CL0002046)
    Fold Change: -0.2421
    Cell Significance Index: -15.6200
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.2545
    Cell Significance Index: -8.0500
  • Cell Name: conjunctival epithelial cell (CL1000432)
    Fold Change: -0.2639
    Cell Significance Index: -3.6000
  • Cell Name: pulmonary alveolar type 2 cell (CL0002063)
    Fold Change: -0.2648
    Cell Significance Index: -2.1900
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.2655
    Cell Significance Index: -5.6400
  • Cell Name: eukaryotic cell (CL0000255)
    Fold Change: -0.2679
    Cell Significance Index: -11.6500
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.2788
    Cell Significance Index: -8.8800
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.2820
    Cell Significance Index: -9.8800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.2935
    Cell Significance Index: -9.6100
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.2960
    Cell Significance Index: -10.8700
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: -0.3025
    Cell Significance Index: -5.1000
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: -0.3051
    Cell Significance Index: -6.6800
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.3112
    Cell Significance Index: -8.0000
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.3141
    Cell Significance Index: -9.0500
  • Cell Name: peg cell (CL4033014)
    Fold Change: -0.3194
    Cell Significance Index: -7.3800
  • Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
    Fold Change: -0.3268
    Cell Significance Index: -6.0400
  • Cell Name: kidney epithelial cell (CL0002518)
    Fold Change: -0.3344
    Cell Significance Index: -9.8500
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.3381
    Cell Significance Index: -13.8600
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.3598
    Cell Significance Index: -7.5100
  • Cell Name: OFF midget ganglion cell (CL4033047)
    Fold Change: -0.3625
    Cell Significance Index: -4.5200
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.3636
    Cell Significance Index: -9.0700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.3666
    Cell Significance Index: -7.9200
  • Cell Name: intestinal epithelial cell (CL0002563)
    Fold Change: -0.3680
    Cell Significance Index: -3.8100
  • Cell Name: GABAergic amacrine cell (CL4030027)
    Fold Change: -0.3943
    Cell Significance Index: -4.8900

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics:** Complement C2 is a serine-type endopeptidase that belongs to the serpin superfamily. It is a key component of the classical pathway of complement activation, where it cleaves and activates C4, generating C4a and C4b fragments. These fragments then form the C3 convertase, a critical enzyme in the complement cascade. Complement C2 also exhibits metal ion binding and protein binding properties, which are essential for its function in regulating complement activation. **Pathways and Functions:** Complement C2 is involved in several key pathways, including: 1. **Activation of C3 and C5:** Complement C2 is crucial for the activation of C3 and C5, which are essential components of the complement cascade. 2. **Complement activation:** Complement C2 is involved in the regulation of complement activation, including the classical pathway, alternative pathway, and lectin pathway. 3. **Apoptotic cell clearance:** Complement C2 plays a role in the clearance of apoptotic cells, which is essential for maintaining tissue homeostasis. 4. **Metal ion binding:** Complement C2 exhibits metal ion binding properties, which are essential for its function in regulating complement activation. **Clinical Significance:** Dysregulation of the complement system, including the C2 gene, has been implicated in various diseases, including: 1. **Autoimmune disorders:** Complement C2 deficiency has been associated with autoimmune disorders, such as systemic lupus erythematosus (SLE) and rheumatoid arthritis (RA). 2. **Infectious diseases:** Complement C2 is involved in the clearance of pathogens, including bacteria and viruses. Dysregulation of the complement system has been implicated in the pathogenesis of infectious diseases. 3. **Cancer:** Complement C2 has been implicated in the clearance of apoptotic cells, which is essential for maintaining tissue homeostasis. Dysregulation of the complement system has been associated with cancer progression. 4. **Neurological disorders:** Complement C2 has been implicated in the pathogenesis of neurological disorders, including Alzheimer's disease and multiple sclerosis. In conclusion, the complement C2 gene plays a critical role in the innate immune response. Its dysregulation has been implicated in various diseases, highlighting the importance of understanding the function and regulation of this gene in maintaining immune homeostasis.

Genular Protein ID: 329913789

Symbol: CO2_HUMAN

Name: Complement C2

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2949737

Title: Primary structure of human complement component C2. Homology to two unrelated protein families.

PubMed ID: 2949737

DOI: 10.1042/bj2390339

PubMed ID: 2493504

Title: cDNA cloning and expression of human complement component C2.

PubMed ID: 2493504

PubMed ID: 8326124

Title: Structure of the human C2 gene.

PubMed ID: 8326124

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 6922702

Title: The purification and properties of the second component of guinea-pig complement.

PubMed ID: 6922702

DOI: 10.1042/bj2050059

PubMed ID: 2997031

Title: DNA polymorphism of the C2 locus.

PubMed ID: 2997031

DOI: 10.1007/bf00430921

PubMed ID: 10734221

Title: A Schistosoma protein, Sh-TOR, is a novel inhibitor of complement which binds human C2.

PubMed ID: 10734221

DOI: 10.1016/s0014-5793(00)01304-1

PubMed ID: 6149575

Title: Structure and activation of complement components C2 and factor B.

PubMed ID: 6149575

DOI: 10.1098/rstb.1984.0091

PubMed ID: 6555044

Title: The reaction of iodine and thiol-blocking reagents with human complement components C2 and factor B. Purification and N-terminal amino acid sequence of a peptide from C2a containing a free thiol group.

PubMed ID: 6555044

DOI: 10.1042/bj2130201

PubMed ID: 6199794

Title: Isolation of cDNA clones for human complement component C2.

PubMed ID: 6199794

DOI: 10.1073/pnas.81.4.1212

PubMed ID: 3643061

Title: Cell-specific expression of the human complement protein factor B gene: evidence for the role of two distinct 5'-flanking elements.

PubMed ID: 3643061

DOI: 10.1016/0092-8674(87)90436-3

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 17027507

Title: Structure of complement component C2A: implications for convertase formation and substrate binding.

PubMed ID: 17027507

DOI: 10.1016/j.str.2006.08.008

PubMed ID: 19237749

Title: The structure of C2b, a fragment of complement component C2 produced during C3 convertase formation.

PubMed ID: 19237749

DOI: 10.1107/s0907444909000389

PubMed ID: 8621452

Title: Type II human complement C2 deficiency. Allele-specific amino acid substitutions (Ser189 --> Phe; Gly444 --> Arg) cause impaired C2 secretion.

PubMed ID: 8621452

DOI: 10.1074/jbc.271.10.5824

PubMed ID: 9670930

Title: A novel type II complement C2 deficiency allele in an African-American family.

PubMed ID: 9670930

PubMed ID: 16518403

Title: Variation in factor B (BF) and complement component 2 (C2) genes is associated with age-related macular degeneration.

PubMed ID: 16518403

DOI: 10.1038/ng1750

Sequence Information:

  • Length: 752
  • Mass: 83268
  • Checksum: 5A96A13E700CF444
  • Sequence:
  • MGPLMVLFCL LFLYPGLADS APSCPQNVNI SGGTFTLSHG WAPGSLLTYS CPQGLYPSPA 
    SRLCKSSGQW QTPGATRSLS KAVCKPVRCP APVSFENGIY TPRLGSYPVG GNVSFECEDG 
    FILRGSPVRQ CRPNGMWDGE TAVCDNGAGH CPNPGISLGA VRTGFRFGHG DKVRYRCSSN 
    LVLTGSSERE CQGNGVWSGT EPICRQPYSY DFPEDVAPAL GTSFSHMLGA TNPTQKTKES 
    LGRKIQIQRS GHLNLYLLLD CSQSVSENDF LIFKESASLM VDRIFSFEIN VSVAIITFAS 
    EPKVLMSVLN DNSRDMTEVI SSLENANYKD HENGTGTNTY AALNSVYLMM NNQMRLLGME 
    TMAWQEIRHA IILLTDGKSN MGGSPKTAVD HIREILNINQ KRNDYLDIYA IGVGKLDVDW 
    RELNELGSKK DGERHAFILQ DTKALHQVFE HMLDVSKLTD TICGVGNMSA NASDQERTPW 
    HVTIKPKSQE TCRGALISDQ WVLTAAHCFR DGNDHSLWRV NVGDPKSQWG KEFLIEKAVI 
    SPGFDVFAKK NQGILEFYGD DIALLKLAQK VKMSTHARPI CLPCTMEANL ALRRPQGSTC 
    RDHENELLNK QSVPAHFVAL NGSKLNINLK MGVEWTSCAE VVSQEKTMFP NLTDVREVVT 
    DQFLCSGTQE DESPCKGESG GAVFLERRFR FFQVGLVSWG LYNPCLGSAD KNSRKRAPRS 
    KVPPPRDFHI NLFRMQPWLR QHLGDVLNFL PL

Genular Protein ID: 2021909498

Symbol: B4DQI1_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 506
  • Mass: 56466
  • Checksum: 3069E8D3AF10CC4D
  • Sequence:
  • MGTRSAIAAP RILCSRGLRS GSARATGSGV ERSPSAAIFS FEINVSVAII TFASEPKVLM 
    SVLNDNSRDM TEVISSLENA NYKDHENGTG TNTYAALNSV YLMMNNQMRL LGMETMAWQE 
    IRHAIILLTD GKSNMGGSPK TAVDHIREIL NINQKRNDYL DIYAIGVGKL DVDWRELNEL 
    GSKKDGERHA FILQDTKALH QVFEHMLDVS KLTDTICGVG NMSANASDQE RTPWHVTIKP 
    KSQETCRGAL ISDQWVLTAA HCFRDGNDHS LWRVNVGDPK SQWGKEFLIE KAVISPGFDV 
    FAKKNQGILE FYGDDIALLK LAQKVKMSTH ARPICLPCTM EANLALRRPQ GSTCRDHENE 
    LLNKQSVPAH FVALNGSKLN INLKMGVEWT SCAEVVSQEK TMFPNLTDVR EVVTDQFLCS 
    GTQEDESPCK GESGGAVFLE RRFRFFQVGL VSWGLYNPCL GSADKNSRKR APRSKVPPPR 
    DFHINLFRMQ PWLRQHLGDV LNFLPL

Genular Protein ID: 2492507287

Symbol: Q53HP3_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 8125298

Title: Oligo-capping: a simple method to replace the cap structure of eukaryotic mRNAs with oligoribonucleotides.

PubMed ID: 8125298

DOI: 10.1016/0378-1119(94)90802-8

PubMed ID: 9373149

Title: Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library.

PubMed ID: 9373149

DOI: 10.1016/S0378-1119(97)00411-3

Sequence Information:

  • Length: 752
  • Mass: 83284
  • Checksum: B9AF4D3E700CF443
  • Sequence:
  • MGPLMVLFCL LFLYPGLADS APSCPQNVNI SGGTFTLSHG WAPGSLLTYS CPQGLYPSPA 
    SRLCKSSGQW QTPGATRSLS KAVCKPVRCP APVSFENGIY TPRLGSYPVG GNVSFECEDG 
    FILRGSPVRQ CRPNGMWDGE TAVCDNGAGH CPNPGISLGA VRTGFRFGHG DKVRYRCSSN 
    LVLTGSSERE CQGNGVWSGT EPICRQPYSY DFPEDVAPAL GTSFSHMLGA TNLTQKTKES 
    LGRKIQIQRS GHLNLYLLLD CSQSVSENDF LIFKESASLM VDRIFSFEIN VSVAIITFAS 
    EPKVLMSVLN DNSRDMTEVI SSLENANYKD HENGTGTNTY AALNSVYLMM NNQMRLLGME 
    TMAWQEIRHA IILLTDGKSN MGGSPKTAVD HIREILNINQ KRNDYLDIYA IGVGKLDVDW 
    RELNELGSKK DGERHAFILQ DTKALHQVFE HMLDVSKLTD TICGVGNMSA NASDQERTPW 
    HVTIKPKSQE TCRGALISDQ WVLTAAHCFR DGNDHSLWRV NVGDPKSQWG KEFLIEKAVI 
    SPGFDVFAKK NQGILEFYGD DIALLKLAQK VKMSTHARPI CLPCTMEANL ALRRPQGSTC 
    RDHENELLNK QSVPAHFVAL NGSKLNINLK MGVEWTSCAE VVSQEKTMFP NLTDVREVVT 
    DQFLCSGTQE DESPCKGESG GAVFLERRFR FFQVGLVSWG LYNPCLGSAD KNSRKRAPRS 
    KVPPPRDFHI NLFRMQPWLR QHLGDVLNFL PL

Genular Protein ID: 1536608682

Symbol: B4DV48_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 723
  • Mass: 80106
  • Checksum: B8D36BDA8762DDD6
  • Sequence:
  • MAGLLGAFSP TPAPRACTHP QHHGCARAAD SGRPQEPPGL CLRRSANVRL PAGFAQAVRC 
    PAPVSFENGI YTPRLGSYPV GGNVSFECED GFILRGSPVR QCRPNGMWDG ETAVCDNGAG 
    HCPNPGISLG AVRTGFRFGH GDKVRYRCSS NLVLTGSSER ECQGNGVWSG TEPICRQPYS 
    YDFPEDVAPA LGTSFSHMLG ATNPTQKTKE SLGRKIQIQR SGHLNLYLLL DCSQSVSEND 
    FLIFKESASP MVDRIFSFEI NVSVAIITFA SEPKVLMSVL NDNSRDMTEV ISSLENANYK 
    DHENGTGTNT YAALNSVYLM MNNQMRLLGM ETMAWQEIRH AIILLTDGKS NMGGSPKTAV 
    DHIREILNIN QKRNDYLDIY AIGVGKLDVD WRELNELGSK KDGERHAFIL QDTKALHQVF 
    EHMLDVSKLT DTICGVGNMS ANASDQERTP WHVTIKPKSQ ETCRGALISD QWVLTAAHCF 
    RDGNDHSLWR VNVGDPKSQW GKEFLIEKAV ISPGFDVFAK KNQGILEFYG DDIALLKLAQ 
    KVKMSTHARP ICLPCTMEAN LALRRPQGST CRDHENELLN KQSVPAHFVA LNGSKLNINL 
    KMGVEWTSCA EVVSQEKTMF PNLTDVREVV TDQFLCSGTQ EDESPCKGES GGAVFLERRF 
    RFFQVGLVSW GLYNPCLGSA DKNSRKRAPR SKVPPPRDFH INLFRMQPWL RQHLGDVLNF 
    LPL

Genular Protein ID: 243375752

Symbol: A0A0G2JL69_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

Sequence Information:

  • Length: 723
  • Mass: 80150
  • Checksum: 40EB07EA5B050DD5
  • Sequence:
  • MAGLLGAFSP TPAPRACTHP QHHGCARAAD SGRPQEPPGL CLRRSANVRL PVGFAQAVRC 
    PAPVSFENGI YTPRLGSYPV GGNVSFECED GFILRGSPVR QCRPNGMWDG ETAVCDNGAG 
    HCPNPGISLG AVRTGFRFGH GDKVRYRCSS NLVLTGSSER ECQGNGVWSG TEPICRQPYS 
    YDFPEDVAPA LGTSFSHMLG ATNPTQKTKE SLGRKIQIQR SGHLNLYLLL DCSQSVSEND 
    FLIFKESASL MVDRIFSFEI NVSVAIITFA SEPKVLMSVL NDNSRDMTEV ISSLENANYK 
    DHENGTGTNT YAALNSVYLM MNNQMRLLGM ETMAWQEIRH AIILLTDGKS NMGGSPKTAV 
    DHIREILNIN QKRNDYLDIY AIGVGKLDVD WRELNELGSK KDGERHAFIL QDTKALHQVF 
    EHMLDVSKLT DTICGVGNMS ANASDQERTP WHVTIKPKSQ ETCRGALISD QWVLTAAHCF 
    RDGNDHSLWR VNVGDPKSQW GKEFLIEKAV ISPGFDVFAK KNQGILEFYG DDIALLKLAQ 
    KVKMSTHARP ICLPCTMEAN LALRRPQGST CRDHENELLN KQSVPAHFVA LNGSKLNINL 
    KMGVEWTSCA EVVSQEKTMF PNLTDVREVV TDQFLCSGTQ EDESPCKGES GGAVFLERRF 
    RFFQVGLVSW GLYNPCLGSA DKNSRKRAPR SKVPPPRDFH INLFRMQPWL RQHLGDVLNF 
    LPL

Genular Protein ID: 1968148032

Symbol: Q8N6L6_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11237011

Title: Initial sequencing and analysis of the human genome.

PubMed ID: 11237011

DOI: 10.1038/35057062

PubMed ID: 14574404

Title: The DNA sequence and analysis of human chromosome 6.

PubMed ID: 14574404

DOI: 10.1038/nature02055

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 15496913

Title: Finishing the euchromatic sequence of the human genome.

PubMed ID: 15496913

DOI: 10.1038/nature03001

Sequence Information:

  • Length: 328
  • Mass: 35451
  • Checksum: 3EE77FE0818959C5
  • Sequence:
  • MGPLMVLFCL LFLYPGLADS APSCPQNVNI SGGTFTLSHG WAPGSLLTYS CPQGLYPSPA 
    SRLCKSSGQW QTPGATRSLS KAVCKPVRCP APVSFENGIY TPRLGSYPVG GNVSFECEDG 
    FILRGSPVRQ CRPNGMWDGE TAVCDNGAGH CPNPGISLGA VRTGFRFGHG DKVRYRCSSN 
    LVLTGSSERE CQGNGVWSGT EPICRQPYSY DFPEDVAPAL GTSFSHMLGA TNPTQKTKES 
    LGRKIQIQRS GHLNLYLLLD CSQSVSENDF LIFKESASLM VDRVRNQESA CSRGLPVLTI 
    SLCLLPLLRT PLTAHLLQEV FSDYTHAM

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.