Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 39.7531
Cell Significance Index: -16.1500 - Cell Name: smooth muscle fiber of ileum (CL1000278)
Fold Change: 37.2361
Cell Significance Index: -17.5800 - Cell Name: theca cell (CL0000503)
Fold Change: 19.5863
Cell Significance Index: 115.0700 - Cell Name: ciliated cell of the bronchus (CL0002332)
Fold Change: 16.8841
Cell Significance Index: -16.1200 - Cell Name: pulmonary interstitial fibroblast (CL0002241)
Fold Change: 13.4780
Cell Significance Index: 83.3900 - Cell Name: interstitial cell of ovary (CL0002094)
Fold Change: 10.5574
Cell Significance Index: 135.2100 - Cell Name: fibroblast of cardiac tissue (CL0002548)
Fold Change: 6.2346
Cell Significance Index: 89.5300 - Cell Name: Leydig cell (CL0000178)
Fold Change: 5.9533
Cell Significance Index: 29.7000 - Cell Name: cortical cell of adrenal gland (CL0002097)
Fold Change: 5.3795
Cell Significance Index: 144.1500 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: 4.8384
Cell Significance Index: 296.6400 - Cell Name: granulocyte monocyte progenitor cell (CL0000557)
Fold Change: 3.5003
Cell Significance Index: 39.1200 - Cell Name: leptomeningeal cell (CL0000708)
Fold Change: 3.4603
Cell Significance Index: 73.9700 - Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
Fold Change: 2.9779
Cell Significance Index: 10.3600 - Cell Name: preadipocyte (CL0002334)
Fold Change: 2.8001
Cell Significance Index: 54.6500 - Cell Name: endocardial cell (CL0002350)
Fold Change: 2.2434
Cell Significance Index: 13.2500 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 1.1659
Cell Significance Index: 115.3400 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: 1.0605
Cell Significance Index: 53.6000 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.8439
Cell Significance Index: 761.9800 - Cell Name: ventricular cardiac muscle cell (CL2000046)
Fold Change: 0.7535
Cell Significance Index: 3.3400 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.6677
Cell Significance Index: 72.6300 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: 0.6240
Cell Significance Index: 37.4600 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.6058
Cell Significance Index: 98.5200 - Cell Name: pancreatic stellate cell (CL0002410)
Fold Change: 0.5638
Cell Significance Index: 7.1000 - Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
Fold Change: 0.4440
Cell Significance Index: 3.5100 - Cell Name: odontoblast (CL0000060)
Fold Change: 0.3946
Cell Significance Index: 50.5900 - Cell Name: prostate stromal cell (CL0002622)
Fold Change: 0.3780
Cell Significance Index: 1.8000 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: 0.3428
Cell Significance Index: 23.7100 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: 0.2972
Cell Significance Index: 22.8100 - Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
Fold Change: 0.2909
Cell Significance Index: 2.7700 - Cell Name: fibroblast of connective tissue of nonglandular part of prostate (CL1000304)
Fold Change: 0.2794
Cell Significance Index: 3.0500 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.2712
Cell Significance Index: 51.6200 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: 0.2532
Cell Significance Index: 45.6500 - Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
Fold Change: 0.2060
Cell Significance Index: 4.9900 - Cell Name: fibroblast of mammary gland (CL0002555)
Fold Change: 0.1524
Cell Significance Index: 4.3700 - Cell Name: BEST4+ enteroycte (CL4030026)
Fold Change: 0.1486
Cell Significance Index: 2.2400 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: 0.1050
Cell Significance Index: 5.4700 - Cell Name: neoplastic cell (CL0001063)
Fold Change: 0.0785
Cell Significance Index: 15.5800 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: 0.0609
Cell Significance Index: 8.3700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: 0.0448
Cell Significance Index: 28.0000 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: 0.0125
Cell Significance Index: 0.3600 - Cell Name: fallopian tube secretory epithelial cell (CL4030006)
Fold Change: 0.0097
Cell Significance Index: 0.1500 - Cell Name: cardiac endothelial cell (CL0010008)
Fold Change: 0.0042
Cell Significance Index: 0.0600 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0011
Cell Significance Index: -0.0400 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0058
Cell Significance Index: -4.2800 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0059
Cell Significance Index: -11.1200 - Cell Name: mesenchymal cell (CL0008019)
Fold Change: -0.0090
Cell Significance Index: -0.1500 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: -0.0092
Cell Significance Index: -0.2000 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0105
Cell Significance Index: -19.4300 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0144
Cell Significance Index: -22.1700 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0162
Cell Significance Index: -9.1200 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0174
Cell Significance Index: -23.6100 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0193
Cell Significance Index: -14.6200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0225
Cell Significance Index: -1.0200 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0234
Cell Significance Index: -14.8800 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.0242
Cell Significance Index: -4.1300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0244
Cell Significance Index: -17.9000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0349
Cell Significance Index: -19.0700 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0357
Cell Significance Index: -16.2200 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0430
Cell Significance Index: -9.0600 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: -0.0446
Cell Significance Index: -16.0000 - Cell Name: epithelial cell of pancreas (CL0000083)
Fold Change: -0.0485
Cell Significance Index: -0.8000 - Cell Name: fibroblast of dermis (CL0002551)
Fold Change: -0.0516
Cell Significance Index: -1.0800 - Cell Name: microcirculation associated smooth muscle cell (CL0008035)
Fold Change: -0.0560
Cell Significance Index: -0.4700 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0603
Cell Significance Index: -17.3600 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.0637
Cell Significance Index: -2.0400 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.0664
Cell Significance Index: -7.7400 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.0747
Cell Significance Index: -1.5500 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: -0.0823
Cell Significance Index: -16.5000 - Cell Name: lung microvascular endothelial cell (CL2000016)
Fold Change: -0.0833
Cell Significance Index: -0.7100 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.0849
Cell Significance Index: -10.4400 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0925
Cell Significance Index: -9.4500 - Cell Name: decidual cell (CL2000002)
Fold Change: -0.0960
Cell Significance Index: -1.5400 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1044
Cell Significance Index: -15.1700 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.1045
Cell Significance Index: -2.2300 - Cell Name: kidney interstitial fibroblast (CL1000692)
Fold Change: -0.1076
Cell Significance Index: -1.2500 - Cell Name: connective tissue cell (CL0002320)
Fold Change: -0.1224
Cell Significance Index: -1.1800 - Cell Name: pancreatic endocrine cell (CL0008024)
Fold Change: -0.1259
Cell Significance Index: -14.3700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1435
Cell Significance Index: -18.5400 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1582
Cell Significance Index: -18.1200 - Cell Name: endothelial cell of venule (CL1000414)
Fold Change: -0.1690
Cell Significance Index: -1.9200 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1781
Cell Significance Index: -18.5400 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.2008
Cell Significance Index: -5.0200 - Cell Name: kidney loop of Henle descending limb epithelial cell (CL1001021)
Fold Change: -0.2275
Cell Significance Index: -18.0200 - Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
Fold Change: -0.2304
Cell Significance Index: -6.4400 - Cell Name: granulosa cell (CL0000501)
Fold Change: -0.2369
Cell Significance Index: -6.2300 - Cell Name: fibroblast of lung (CL0002553)
Fold Change: -0.2389
Cell Significance Index: -2.8400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2411
Cell Significance Index: -17.9700 - Cell Name: skeletal muscle fiber (CL0008002)
Fold Change: -0.2560
Cell Significance Index: -6.5800 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: -0.2756
Cell Significance Index: -18.5300 - Cell Name: immature innate lymphoid cell (CL0001082)
Fold Change: -0.2927
Cell Significance Index: -3.6200 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.3166
Cell Significance Index: -19.4600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3277
Cell Significance Index: -18.3900 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.3449
Cell Significance Index: -16.2100 - Cell Name: hepatic stellate cell (CL0000632)
Fold Change: -0.3635
Cell Significance Index: -3.7500 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.3657
Cell Significance Index: -19.2000 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: -0.3714
Cell Significance Index: -9.9400 - Cell Name: Sertoli cell (CL0000216)
Fold Change: -0.3750
Cell Significance Index: -5.2600 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.3856
Cell Significance Index: -17.9800 - Cell Name: cardiac muscle cell (CL0000746)
Fold Change: -0.3874
Cell Significance Index: -5.7200 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.3942
Cell Significance Index: -20.4800
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 3289066210
Symbol: CO7_HUMAN
Name: Complement component C7
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 3335508
Title: The structure of human complement component C7 and the C5b-7 complex.
PubMed ID: 3335508
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 7730625
Title: Structure of the human C7 gene and comparison with the C6, C8A, C8B and C9 genes.
PubMed ID: 7730625
PubMed ID: 10551839
Title: The four terminal components of the complement system are C-mannosylated on multiple tryptophan residues.
PubMed ID: 10551839
PubMed ID: 14760718
Title: Screening for N-glycosylated proteins by liquid chromatography mass spectrometry.
PubMed ID: 14760718
PubMed ID: 16335952
Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.
PubMed ID: 16335952
DOI: 10.1021/pr0502065
PubMed ID: 19139490
Title: A strategy for precise and large scale identification of core fucosylated glycoproteins.
PubMed ID: 19139490
PubMed ID: 22171320
Title: Human urinary glycoproteomics; attachment site specific analysis of N- and O-linked glycosylations by CID and ECD.
PubMed ID: 22171320
PubMed ID: 19419965
Title: Solution structure of factor I-like modules from complement C7 reveals a pair of follistatin domains in compact pseudosymmetric arrangement.
PubMed ID: 19419965
PubMed ID: 8871666
Title: Molecular bases of combined subtotal deficiencies of C6 and C7: their effects in combination with other C6 and C7 deficiencies.
PubMed ID: 8871666
PubMed ID: 9218625
Title: Molecular bases of C7 deficiency: three different defects.
PubMed ID: 9218625
PubMed ID: 9856499
Title: Complement C7 deficiency: seven further molecular defects and their associated marker haplotypes.
PubMed ID: 9856499
PubMed ID: 22028381
Title: Quantitative detection of single amino acid polymorphisms by targeted proteomics.
PubMed ID: 22028381
DOI: 10.1093/jmcb/mjr024
Sequence Information:
- Length: 843
- Mass: 93518
- Checksum: DBD5D7C92DF71FA5
- Sequence:
MKVISLFILV GFIGEFQSFS SASSPVNCQW DFYAPWSECN GCTKTQTRRR SVAVYGQYGG QPCVGNAFET QSCEPTRGCP TEEGCGERFR CFSGQCISKS LVCNGDSDCD EDSADEDRCE DSERRPSCDI DKPPPNIELT GNGYNELTGQ FRNRVINTKS FGGQCRKVFS GDGKDFYRLS GNVLSYTFQV KINNDFNYEF YNSTWSYVKH TSTEHTSSSR KRSFFRSSSS SSRSYTSHTN EIHKGKSYQL LVVENTVEVA QFINNNPEFL QLAEPFWKEL SHLPSLYDYS AYRRLIDQYG THYLQSGSLG GEYRVLFYVD SEKLKQNDFN SVEEKKCKSS GWHFVVKFSS HGCKELENAL KAASGTQNNV LRGEPFIRGG GAGFISGLSY LELDNPAGNK RRYSAWAESV TNLPQVIKQK LTPLYELVKE VPCASVKKLY LKWALEEYLD EFDPCHCRPC QNGGLATVEG THCLCHCKPY TFGAACEQGV LVGNQAGGVD GGWSCWSSWS PCVQGKKTRS RECNNPPPSG GGRSCVGETT ESTQCEDEEL EHLRLLEPHC FPLSLVPTEF CPSPPALKDG FVQDEGTMFP VGKNVVYTCN EGYSLIGNPV ARCGEDLRWL VGEMHCQKIA CVLPVLMDGI QSHPQKPFYT VGEKVTVSCS GGMSLEGPSA FLCGSSLKWS PEMKNARCVQ KENPLTQAVP KCQRWEKLQN SRCVCKMPYE CGPSLDVCAQ DERSKRILPL TVCKMHVLHC QGRNYTLTGR DSCTLPASAE KACGACPLWG KCDAESSKCV CREASECEEE GFSICVEVNG KEQTMSECEA GALRCRGQSI SVTSIRPCAA ETQ
Genular Protein ID: 784520377
Symbol: Q05CI3_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
Sequence Information:
- Length: 343
- Mass: 39168
- Checksum: 466484955D295E72
- Sequence:
MKVISLFILV GFIGEFQSFS SASSPVNCQW DFYAPWSECN GCTKTQTRRR SVAVYGQYGG QPCVGNAFET QSCEPTRGCP TEEGCGERFR CFSGQCISKS LVCNGDSDCD EDSADEDRCE DSERRPSCDI DKPPPNIELT GNGYNELTGQ FRNRVINTKS FGGQCRKVFS GDGKDFYRLS GNVLSYTFQV KINNDFNYEF YNSTWSYVKH TSTEHTSSSR KRSFFRSSSS SSRSYTSHTN EIHKGKSYQL LVVENTVEVA QFINNNPEFL QLAEPFWKEL SHLPSLYDYS AYRRLIDQYG THYLQSGSLG GEYRVLFYVD SEKLKQNDFN SVEKKKKKKK KKK
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.