Details for: C8B

Gene ID: 732

Symbol: C8B

Ensembl ID: ENSG00000021852

Description: complement C8 beta chain

Associated with

Cells (max top 100)

(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)

  • Cell Name: liver dendritic cell (CL2000055)
    Fold Change: 2.8014
    Cell Significance Index: 7.3900
  • Cell Name: centrilobular region hepatocyte (CL0019029)
    Fold Change: 2.6774
    Cell Significance Index: 45.1000
  • Cell Name: neoplastic cell (CL0001063)
    Fold Change: 1.1916
    Cell Significance Index: 236.4700
  • Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
    Fold Change: 1.1814
    Cell Significance Index: 25.1600
  • Cell Name: intrahepatic cholangiocyte (CL0002538)
    Fold Change: 1.0727
    Cell Significance Index: 4.0400
  • Cell Name: paneth cell of epithelium of small intestine (CL1000343)
    Fold Change: 0.9492
    Cell Significance Index: 20.5700
  • Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
    Fold Change: 0.6267
    Cell Significance Index: 8.9800
  • Cell Name: transit amplifying cell of colon (CL0009011)
    Fold Change: 0.5957
    Cell Significance Index: 19.0800
  • Cell Name: BEST4+ enteroycte (CL4030026)
    Fold Change: 0.5594
    Cell Significance Index: 8.4300
  • Cell Name: cytotoxic T cell (CL0000910)
    Fold Change: 0.4652
    Cell Significance Index: 6.7800
  • Cell Name: periportal region hepatocyte (CL0019026)
    Fold Change: 0.4268
    Cell Significance Index: 6.3000
  • Cell Name: midzonal region hepatocyte (CL0019028)
    Fold Change: 0.4246
    Cell Significance Index: 2.4500
  • Cell Name: cholangiocyte (CL1000488)
    Fold Change: 0.1814
    Cell Significance Index: 1.7900
  • Cell Name: hepatic pit cell (CL2000054)
    Fold Change: 0.1708
    Cell Significance Index: 0.4600
  • Cell Name: gut absorptive cell (CL0000677)
    Fold Change: 0.1343
    Cell Significance Index: 8.0600
  • Cell Name: inflammatory macrophage (CL0000863)
    Fold Change: 0.1077
    Cell Significance Index: 0.8300
  • Cell Name: endothelial cell of pericentral hepatic sinusoid (CL0019022)
    Fold Change: 0.1013
    Cell Significance Index: 0.8000
  • Cell Name: endothelial cell of hepatic sinusoid (CL1000398)
    Fold Change: 0.0899
    Cell Significance Index: 0.8600
  • Cell Name: cerebellar granule cell (CL0001031)
    Fold Change: 0.0770
    Cell Significance Index: 1.3200
  • Cell Name: thymocyte (CL0000893)
    Fold Change: 0.0666
    Cell Significance Index: 0.8400
  • Cell Name: hepatoblast (CL0005026)
    Fold Change: 0.0571
    Cell Significance Index: 0.9600
  • Cell Name: germinal center B cell (CL0000844)
    Fold Change: 0.0509
    Cell Significance Index: 0.3600
  • Cell Name: epithelial cell of small intestine (CL0002254)
    Fold Change: 0.0480
    Cell Significance Index: 7.8000
  • Cell Name: chorionic trophoblast cell (CL0011101)
    Fold Change: 0.0435
    Cell Significance Index: 0.1400
  • Cell Name: Purkinje cell (CL0000121)
    Fold Change: 0.0368
    Cell Significance Index: 0.8100
  • Cell Name: dopaminergic neuron (CL0000700)
    Fold Change: 0.0223
    Cell Significance Index: 6.4200
  • Cell Name: cortical cell of adrenal gland (CL0002097)
    Fold Change: 0.0190
    Cell Significance Index: 0.5100
  • Cell Name: alternatively activated macrophage (CL0000890)
    Fold Change: 0.0151
    Cell Significance Index: 0.1400
  • Cell Name: erythroblast (CL0000765)
    Fold Change: 0.0126
    Cell Significance Index: 0.1500
  • Cell Name: microfold cell of epithelium of small intestine (CL1000353)
    Fold Change: 0.0074
    Cell Significance Index: 0.5100
  • Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
    Fold Change: 0.0067
    Cell Significance Index: 0.5000
  • Cell Name: transit amplifying cell of small intestine (CL0009012)
    Fold Change: 0.0034
    Cell Significance Index: 0.0700
  • Cell Name: Kupffer cell (CL0000091)
    Fold Change: 0.0033
    Cell Significance Index: 0.0300
  • Cell Name: endothelial cell of periportal hepatic sinusoid (CL0019021)
    Fold Change: 0.0014
    Cell Significance Index: 0.0100
  • Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
    Fold Change: 0.0009
    Cell Significance Index: 0.3300
  • Cell Name: hepatic stellate cell (CL0000632)
    Fold Change: 0.0005
    Cell Significance Index: 0.0100
  • Cell Name: cell in vitro (CL0001034)
    Fold Change: 0.0004
    Cell Significance Index: 0.2200
  • Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
    Fold Change: 0.0000
    Cell Significance Index: 0.0000
  • Cell Name: pigmented epithelial cell (CL0000529)
    Fold Change: 0.0000
    Cell Significance Index: -0.0500
  • Cell Name: anterior lens cell (CL0002223)
    Fold Change: -0.0002
    Cell Significance Index: -0.4100
  • Cell Name: lens epithelial cell (CL0002224)
    Fold Change: -0.0002
    Cell Significance Index: -0.2700
  • Cell Name: pancreatic A cell (CL0000171)
    Fold Change: -0.0003
    Cell Significance Index: -0.2200
  • Cell Name: secondary lens fiber (CL0002225)
    Fold Change: -0.0004
    Cell Significance Index: -0.5600
  • Cell Name: pulmonary alveolar epithelial cell (CL0000322)
    Fold Change: -0.0008
    Cell Significance Index: -0.6000
  • Cell Name: type B pancreatic cell (CL0000169)
    Fold Change: -0.0009
    Cell Significance Index: -0.5300
  • Cell Name: pancreatic ductal cell (CL0002079)
    Fold Change: -0.0012
    Cell Significance Index: -0.1400
  • Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
    Fold Change: -0.0018
    Cell Significance Index: -1.1500
  • Cell Name: pancreatic acinar cell (CL0002064)
    Fold Change: -0.0020
    Cell Significance Index: -0.3400
  • Cell Name: ciliary muscle cell (CL1000443)
    Fold Change: -0.0022
    Cell Significance Index: -1.0000
  • Cell Name: pancreatic D cell (CL0000173)
    Fold Change: -0.0029
    Cell Significance Index: -0.6200
  • Cell Name: obsolete epithelial cell of alveolus of lung (CL0010003)
    Fold Change: -0.0030
    Cell Significance Index: -0.0700
  • Cell Name: alveolar macrophage (CL0000583)
    Fold Change: -0.0034
    Cell Significance Index: -0.0300
  • Cell Name: enterocyte of epithelium of small intestine (CL1000334)
    Fold Change: -0.0035
    Cell Significance Index: -0.1000
  • Cell Name: hippocampal granule cell (CL0001033)
    Fold Change: -0.0038
    Cell Significance Index: -0.2600
  • Cell Name: pigmented ciliary epithelial cell (CL0002303)
    Fold Change: -0.0045
    Cell Significance Index: -0.6500
  • Cell Name: stromal cell of ovary (CL0002132)
    Fold Change: -0.0045
    Cell Significance Index: -0.6200
  • Cell Name: acinar cell of salivary gland (CL0002623)
    Fold Change: -0.0049
    Cell Significance Index: -0.2300
  • Cell Name: hepatocyte (CL0000182)
    Fold Change: -0.0050
    Cell Significance Index: -0.0700
  • Cell Name: medium spiny neuron (CL1001474)
    Fold Change: -0.0052
    Cell Significance Index: -0.0700
  • Cell Name: lactocyte (CL0002325)
    Fold Change: -0.0052
    Cell Significance Index: -0.6700
  • Cell Name: intermediate cell of urothelium (CL4030055)
    Fold Change: -0.0056
    Cell Significance Index: -1.0100
  • Cell Name: myeloid lineage restricted progenitor cell (CL0000839)
    Fold Change: -0.0071
    Cell Significance Index: -0.1000
  • Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
    Fold Change: -0.0086
    Cell Significance Index: -0.3000
  • Cell Name: alpha-beta T cell (CL0000789)
    Fold Change: -0.0094
    Cell Significance Index: -0.0800
  • Cell Name: cardiac muscle myoblast (CL0000513)
    Fold Change: -0.0100
    Cell Significance Index: -0.7700
  • Cell Name: basal cell of urothelium (CL1000486)
    Fold Change: -0.0101
    Cell Significance Index: -1.2500
  • Cell Name: lens fiber cell (CL0011004)
    Fold Change: -0.0107
    Cell Significance Index: -0.3400
  • Cell Name: neuron associated cell (CL0000095)
    Fold Change: -0.0117
    Cell Significance Index: -0.4800
  • Cell Name: fibro/adipogenic progenitor cell (CL0009099)
    Fold Change: -0.0120
    Cell Significance Index: -0.6000
  • Cell Name: retinal progenitor cell (CL0002672)
    Fold Change: -0.0123
    Cell Significance Index: -0.6900
  • Cell Name: epithelial cell of pancreas (CL0000083)
    Fold Change: -0.0127
    Cell Significance Index: -0.2100
  • Cell Name: forebrain neuroblast (CL1000042)
    Fold Change: -0.0137
    Cell Significance Index: -0.8400
  • Cell Name: basophil (CL0000767)
    Fold Change: -0.0141
    Cell Significance Index: -0.1300
  • Cell Name: leukocyte (CL0000738)
    Fold Change: -0.0141
    Cell Significance Index: -0.2400
  • Cell Name: CD14-low, CD16-positive monocyte (CL0002396)
    Fold Change: -0.0153
    Cell Significance Index: -0.3700
  • Cell Name: skeletal muscle fiber (CL0008002)
    Fold Change: -0.0153
    Cell Significance Index: -0.3900
  • Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
    Fold Change: -0.0159
    Cell Significance Index: -0.7500
  • Cell Name: basal epithelial cell of tracheobronchial tree (CL0002329)
    Fold Change: -0.0161
    Cell Significance Index: -0.4500
  • Cell Name: indirect pathway medium spiny neuron (CL4023029)
    Fold Change: -0.0165
    Cell Significance Index: -0.7300
  • Cell Name: hippocampal pyramidal neuron (CL1001571)
    Fold Change: -0.0166
    Cell Significance Index: -0.4800
  • Cell Name: L6b glutamatergic cortical neuron (CL4023038)
    Fold Change: -0.0173
    Cell Significance Index: -0.5700
  • Cell Name: ON-bipolar cell (CL0000749)
    Fold Change: -0.0177
    Cell Significance Index: -0.2000
  • Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
    Fold Change: -0.0182
    Cell Significance Index: -0.5800
  • Cell Name: direct pathway medium spiny neuron (CL4023026)
    Fold Change: -0.0193
    Cell Significance Index: -0.7300
  • Cell Name: L2/3 intratelencephalic projecting glutamatergic neuron (CL4030059)
    Fold Change: -0.0195
    Cell Significance Index: -0.2600
  • Cell Name: near-projecting glutamatergic cortical neuron (CL4023012)
    Fold Change: -0.0200
    Cell Significance Index: -0.5000
  • Cell Name: stratified epithelial cell (CL0000079)
    Fold Change: -0.0204
    Cell Significance Index: -0.7500
  • Cell Name: skeletal muscle satellite cell (CL0000594)
    Fold Change: -0.0218
    Cell Significance Index: -0.2300
  • Cell Name: preadipocyte (CL0002334)
    Fold Change: -0.0220
    Cell Significance Index: -0.4300
  • Cell Name: chandelier pvalb GABAergic cortical interneuron (CL4023036)
    Fold Change: -0.0230
    Cell Significance Index: -0.4800
  • Cell Name: fibroblast of mammary gland (CL0002555)
    Fold Change: -0.0230
    Cell Significance Index: -0.6600
  • Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
    Fold Change: -0.0231
    Cell Significance Index: -0.4900
  • Cell Name: erythrocyte (CL0000232)
    Fold Change: -0.0235
    Cell Significance Index: -0.6000
  • Cell Name: mature NK T cell (CL0000814)
    Fold Change: -0.0237
    Cell Significance Index: -0.2700
  • Cell Name: lamp5 GABAergic cortical interneuron (CL4023011)
    Fold Change: -0.0245
    Cell Significance Index: -0.5300
  • Cell Name: VIP GABAergic cortical interneuron (CL4023016)
    Fold Change: -0.0249
    Cell Significance Index: -0.5000
  • Cell Name: sncg GABAergic cortical interneuron (CL4023015)
    Fold Change: -0.0249
    Cell Significance Index: -0.4900
  • Cell Name: basal cell of epidermis (CL0002187)
    Fold Change: -0.0252
    Cell Significance Index: -0.3800
  • Cell Name: type I muscle cell (CL0002211)
    Fold Change: -0.0254
    Cell Significance Index: -0.6200
  • Cell Name: sst GABAergic cortical interneuron (CL4023017)
    Fold Change: -0.0258
    Cell Significance Index: -0.5100

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Cell ID: Standard Cell Ontology term used for mapping and comparing cells across experiments. Ensures consistency in analyzing cellular functions across tissues.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.

Other Information

**Key Characteristics** The C8B gene exhibits several key characteristics that are essential to its function in the complement system: 1. **Alternative and classical pathways**: C8B is involved in both the alternative and classical pathways of complement activation, which are two distinct mechanisms of initiating the complement cascade. 2. **Terminal pathway**: As a terminal component, C8B plays a critical role in the formation of the MAC, which is responsible for cell lysis and clearance of pathogens. 3. **Membrane attack complex formation**: The C8B gene encodes for the beta chain of the C8 component, which, along with C9, forms the MAC that inserts into the target cell membrane, causing cell lysis. 4. **Regulation of complement cascade**: The C8B gene is involved in regulating the complement cascade, ensuring that the immune response is tightly controlled and does not cause excessive tissue damage. **Pathways and Functions** The C8B gene is involved in several key pathways and functions, including: 1. **Complement activation**: The C8B gene is involved in the activation of the complement system, which is a critical component of the innate immune response. 2. **Immune response regulation**: The C8B gene plays a role in regulating the immune response, ensuring that it is not excessive and does not cause tissue damage. 3. **Killing of cells of another organism**: The C8B gene is involved in the killing of cells of another organism, which is a critical component of the host's defense against pathogens. 4. **Extracellular vesicle formation**: The C8B gene is involved in the formation of extracellular vesicles, which are small membrane-bound particles that can transmit signals between cells. **Clinical Significance** The C8B gene has significant clinical implications, including: 1. **Complement dysregulation**: Dysregulation of the complement system, including the C8B gene, has been implicated in various diseases, including autoimmune disorders, such as lupus and rheumatoid arthritis, and inflammatory conditions, such as atherosclerosis. 2. **Infectious diseases**: The C8B gene is involved in the clearance of pathogens, and dysregulation of the complement system can lead to increased susceptibility to infections. 3. **Cancer**: The C8B gene has been implicated in the regulation of the immune response, and dysregulation of the complement system has been linked to the development of cancer. 4. **Transplantation**: The C8B gene plays a critical role in the regulation of the immune response, and dysregulation of the complement system can lead to rejection of transplanted organs. In conclusion, the C8B gene is a critical component of the complement system, and its dysregulation can have significant clinical implications. Further research is needed to fully understand the role of the C8B gene in immune responses and to explore its potential as a therapeutic target for various diseases.

Genular Protein ID: 2702548213

Symbol: CO8B_HUMAN

Name: Complement component C8 beta chain

UniProtKB Accession Codes:

P07358 A1L4K7

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ComplexPortal 1 DMDM 1 DNASU 1 DisGeNET 1 DrugBank 3 EMBL 6 EMDB 9 Ensembl 2 EvolutionaryTrace 1 ExpressionAtlas 1 GO 14 Gene3D 2 GeneCards 1 GeneTree 1 GenomeRNAi 1 GlyConnect 1 GlyCosmos 1 GlyGen 1 HGNC 1 HPA 1 InParanoid 1 IntAct 1 InterPro 9 KEGG 1 MANE-Select 1 MIM 3 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 8 PDBsum 8 PIR 1 PRINTS 1 PRO 1 PROSITE 6 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 4 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 2 SIGNOR 1 SMART 3 SMR 1 STRING 1 SUPFAM 2 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 2820472

Title: Complementary DNA and derived amino acid sequence of the beta subunit of human complement protein C8: identification of a close structural and ancestral relationship to the alpha subunit and C9.

PubMed ID: 2820472

DOI: 10.1021/bi00386a047

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3651397

Title: Complementary DNA cloning of complement C8 beta and its sequence homology to C9.

PubMed ID: 3651397

DOI: 10.1021/bi00386a045

PubMed ID: 7440581

Title: The eighth component of human complement. Purification and physicochemical characterization of its unusual subunit structure.

PubMed ID: 7440581

DOI: 10.1016/s0021-9258(19)70233-6

PubMed ID: 10551839

Title: The four terminal components of the complement system are C-mannosylated on multiple tryptophan residues.

PubMed ID: 10551839

DOI: 10.1074/jbc.274.46.32786

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 21454577

Title: Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.

PubMed ID: 21454577

DOI: 10.1074/jbc.m111.219766

PubMed ID: 8131848

Title: Human complement component C8. Molecular basis of the beta-chain polymorphism.

PubMed ID: 8131848

DOI: 10.1016/0014-5793(94)80140-1

Sequence Information:

  • Length: 591
  • Mass: 66948
  • Checksum: 1DBC54FF833AF6BF
  • Sequence:
    • MKNSRTWAWR APVELFLLCA ALGCLSLPGS RGERPHSFGS NAVNKSFAKS RQMRSVDVTL 
MPIDCELSSW SSWTTCDPCQ KKRYRYAYLL QPSQFHGEPC NFSDKEVEDC VTNRPCGSQV 
RCEGFVCAQT GRCVNRRLLC NGDNDCGDQS DEANCRRIYK KCQHEMDQYW GIGSLASGIN 
LFTNSFEGPV LDHRYYAGGC SPHYILNTRF RKPYNVESYT PQTQGKYEFI LKEYESYSDF 
ERNVTEKMAS KSGFSFGFKI PGIFELGISS QSDRGKHYIR RTKRFSHTKS VFLHARSDLE 
VAHYKLKPRS LMLHYEFLQR VKRLPLEYSY GEYRDLFRDF GTHYITEAVL GGIYEYTLVM 
NKEAMERGDY TLNNVHACAK NDFKIGGAIE EVYVSLGVSV GKCRGILNEI KDRNKRDTMV 
EDLVVLVRGG ASEHITTLAY QELPTADLMQ EWGDAVQYNP AIIKVKVEPL YELVTATDFA 
YSSTVRQNMK QALEEFQKEV SSCHCAPCQG NGVPVLKGSR CDCICPVGSQ GLACEVSYRK 
NTPIDGKWNC WSNWSSCSGR RKTRQRQCNN PPPQNGGSPC SGPASETLDC S

Genular Protein ID: 1614822922

Symbol: B7Z550_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z550

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 4 GO 5 Gene3D 2 InterPro 9 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 3 RefSeq 1 SAM 1 SMART 2 SUPFAM 2

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 529
  • Mass: 60140
  • Checksum: 684E69408EB2A118
  • Sequence:
    • MDTCMTLAFT LSGRFFMLLS QYRYAYLLQP SQFHGEPCNF SDKEVEDCVT NRPCRSQVRC 
EGFVCAQTGR CVNRRLLCNG DNDCGDQSDE ANCRRIYKKC QHEMDQYWGI GSLASGINLF 
TNSFEGPVLD HRYYAGGCSP HYILNTRFRK PYNVESYTPQ TQGKYEFILK EYESYSDFER 
NVTEKMASKS GFSFGFKIPG IFELGISSQS DRGKHYIRRT KRFSHTKSVF LHARSDLEVA 
HYKLKPRSLM LHYEFLQRVK RLPLEYSYGE YRDLFRDFGT HYITEAVLGG IYEYTLVMNK 
EAMERGDYTL NNVHACAKND FKIGGAIEEV YVSLGVSVGK CRGILNEIKD RNKRDTMVED 
LVVLVRGGAS EHITTLAYQE LPTADLMQEW GDAVQYNPAI IKVKVEPLYE LVTATDFAYS 
STVRQNMKQA LEEFQKEVSS CHCAPCQGNG VPVLKGSRCD CICPVGSQGL ACEVSYRKNT 
PIDGKWNCWS NWSSCSGRRK TRQRQCNNPP PQNGGSPCSG PASETLDCS

Genular Protein ID: 1381035942

Symbol: B7Z555_HUMAN

Name: N/A

UniProtKB Accession Codes:

B7Z555

Database IDs:

ARBA 13 AlphaFoldDB 1 BioGRID-ORCS 1 CDD 1 CTD 1 DNASU 1 DisGeNET 1 EMBL 2 GO 5 Gene3D 2 InterPro 9 NCBI Taxonomy 1 OrthoDB 1 PANTHER 2 PRINTS 2 PROSITE 6 PROSITE-ProRule 1 PeptideAtlas 1 Pfam 4 RefSeq 1 SAM 1 SMART 3 SUPFAM 2

Sequence Information:

  • Length: 539
  • Mass: 61330
  • Checksum: 5AFF682D2C9E59E5
  • Sequence:
    • MRSVDVTLMP IDCELSSWSS WTTCDPCQKK RYRYAYLLQP SQFHGEPCNF SDKEVEDCVT 
NRPCRSQVRC EGFVCAQTGR CVNRRLLCNG DNDCGDQSDE ANCRRIYKKC QHEMDQYWGI 
GSLASGINLF TNSFEGPVLD HRYYAGGCSP HYILNTRFRK PYNVESYTPQ TQGKYEFILK 
EYESYSDFER NVTEKMASKS GFSFGFKIPG IFELGISSQS DRGKHYIRRT KRFSHTKSVF 
LHARSDLEVA HYKLKPRSLM LHYEFLQRVK RLPLEYSYGE YRDLFRDFGT HYITEAVLGG 
IYEYTLVMNK EAMERGDYTL NNVHACAKND FKIGGAIEEV YVSLGVSVGK CRGILNEIKD 
RNKRDTMVED LVVLVRGGAS EHITTLAYQE LPTADLMQEW GDAVQYNPAI IKVKVEPLYE 
LVTATDFAYS STVRQNMKQA LEEFQKEVSS CHCAPCQGNG VPVLKGSRCD CICPVGSQGL 
ACEVSYRKNT PIDGKWNCWS NWSSCSGRRK TRQRQCNNPP PQNGGSPCSG PASETLDCS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.