Details for: C8B

Gene ID: 732

Symbol: C8B

Ensembl ID: ENSG00000021852

Description: complement C8 beta chain

Associated with

Other Information

Genular Protein ID: 2702548213

Symbol: CO8B_HUMAN

Name: Complement component C8 beta chain

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 2820472

Title: Complementary DNA and derived amino acid sequence of the beta subunit of human complement protein C8: identification of a close structural and ancestral relationship to the alpha subunit and C9.

PubMed ID: 2820472

DOI: 10.1021/bi00386a047

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16710414

Title: The DNA sequence and biological annotation of human chromosome 1.

PubMed ID: 16710414

DOI: 10.1038/nature04727

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 3651397

Title: Complementary DNA cloning of complement C8 beta and its sequence homology to C9.

PubMed ID: 3651397

DOI: 10.1021/bi00386a045

PubMed ID: 7440581

Title: The eighth component of human complement. Purification and physicochemical characterization of its unusual subunit structure.

PubMed ID: 7440581

DOI: 10.1016/s0021-9258(19)70233-6

PubMed ID: 10551839

Title: The four terminal components of the complement system are C-mannosylated on multiple tryptophan residues.

PubMed ID: 10551839

DOI: 10.1074/jbc.274.46.32786

PubMed ID: 16335952

Title: Human plasma N-glycoproteome analysis by immunoaffinity subtraction, hydrazide chemistry, and mass spectrometry.

PubMed ID: 16335952

DOI: 10.1021/pr0502065

PubMed ID: 19159218

Title: Glycoproteomics analysis of human liver tissue by combination of multiple enzyme digestion and hydrazide chemistry.

PubMed ID: 19159218

DOI: 10.1021/pr8008012

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 21454577

Title: Structure of human C8 protein provides mechanistic insight into membrane pore formation by complement.

PubMed ID: 21454577

DOI: 10.1074/jbc.m111.219766

PubMed ID: 8131848

Title: Human complement component C8. Molecular basis of the beta-chain polymorphism.

PubMed ID: 8131848

DOI: 10.1016/0014-5793(94)80140-1

Sequence Information:

  • Length: 591
  • Mass: 66948
  • Checksum: 1DBC54FF833AF6BF
  • Sequence:
  • MKNSRTWAWR APVELFLLCA ALGCLSLPGS RGERPHSFGS NAVNKSFAKS RQMRSVDVTL 
    MPIDCELSSW SSWTTCDPCQ KKRYRYAYLL QPSQFHGEPC NFSDKEVEDC VTNRPCGSQV 
    RCEGFVCAQT GRCVNRRLLC NGDNDCGDQS DEANCRRIYK KCQHEMDQYW GIGSLASGIN 
    LFTNSFEGPV LDHRYYAGGC SPHYILNTRF RKPYNVESYT PQTQGKYEFI LKEYESYSDF 
    ERNVTEKMAS KSGFSFGFKI PGIFELGISS QSDRGKHYIR RTKRFSHTKS VFLHARSDLE 
    VAHYKLKPRS LMLHYEFLQR VKRLPLEYSY GEYRDLFRDF GTHYITEAVL GGIYEYTLVM 
    NKEAMERGDY TLNNVHACAK NDFKIGGAIE EVYVSLGVSV GKCRGILNEI KDRNKRDTMV 
    EDLVVLVRGG ASEHITTLAY QELPTADLMQ EWGDAVQYNP AIIKVKVEPL YELVTATDFA 
    YSSTVRQNMK QALEEFQKEV SSCHCAPCQG NGVPVLKGSR CDCICPVGSQ GLACEVSYRK 
    NTPIDGKWNC WSNWSSCSGR RKTRQRQCNN PPPQNGGSPC SGPASETLDC S

Genular Protein ID: 1614822922

Symbol: B7Z550_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 11181995

Title: The sequence of the human genome.

PubMed ID: 11181995

DOI: 10.1126/science.1058040

Sequence Information:

  • Length: 529
  • Mass: 60140
  • Checksum: 684E69408EB2A118
  • Sequence:
  • MDTCMTLAFT LSGRFFMLLS QYRYAYLLQP SQFHGEPCNF SDKEVEDCVT NRPCRSQVRC 
    EGFVCAQTGR CVNRRLLCNG DNDCGDQSDE ANCRRIYKKC QHEMDQYWGI GSLASGINLF 
    TNSFEGPVLD HRYYAGGCSP HYILNTRFRK PYNVESYTPQ TQGKYEFILK EYESYSDFER 
    NVTEKMASKS GFSFGFKIPG IFELGISSQS DRGKHYIRRT KRFSHTKSVF LHARSDLEVA 
    HYKLKPRSLM LHYEFLQRVK RLPLEYSYGE YRDLFRDFGT HYITEAVLGG IYEYTLVMNK 
    EAMERGDYTL NNVHACAKND FKIGGAIEEV YVSLGVSVGK CRGILNEIKD RNKRDTMVED 
    LVVLVRGGAS EHITTLAYQE LPTADLMQEW GDAVQYNPAI IKVKVEPLYE LVTATDFAYS 
    STVRQNMKQA LEEFQKEVSS CHCAPCQGNG VPVLKGSRCD CICPVGSQGL ACEVSYRKNT 
    PIDGKWNCWS NWSSCSGRRK TRQRQCNNPP PQNGGSPCSG PASETLDCS

Genular Protein ID: 1381035942

Symbol: B7Z555_HUMAN

Name: N/A

UniProtKB Accession Codes:

Database IDs:

Sequence Information:

  • Length: 539
  • Mass: 61330
  • Checksum: 5AFF682D2C9E59E5
  • Sequence:
  • MRSVDVTLMP IDCELSSWSS WTTCDPCQKK RYRYAYLLQP SQFHGEPCNF SDKEVEDCVT 
    NRPCRSQVRC EGFVCAQTGR CVNRRLLCNG DNDCGDQSDE ANCRRIYKKC QHEMDQYWGI 
    GSLASGINLF TNSFEGPVLD HRYYAGGCSP HYILNTRFRK PYNVESYTPQ TQGKYEFILK 
    EYESYSDFER NVTEKMASKS GFSFGFKIPG IFELGISSQS DRGKHYIRRT KRFSHTKSVF 
    LHARSDLEVA HYKLKPRSLM LHYEFLQRVK RLPLEYSYGE YRDLFRDFGT HYITEAVLGG 
    IYEYTLVMNK EAMERGDYTL NNVHACAKND FKIGGAIEEV YVSLGVSVGK CRGILNEIKD 
    RNKRDTMVED LVVLVRGGAS EHITTLAYQE LPTADLMQEW GDAVQYNPAI IKVKVEPLYE 
    LVTATDFAYS STVRQNMKQA LEEFQKEVSS CHCAPCQGNG VPVLKGSRCD CICPVGSQGL 
    ACEVSYRKNT PIDGKWNCWS NWSSCSGRRK TRQRQCNNPP PQNGGSPCSG PASETLDCS

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.