Details for: C8G

Gene ID: 733

Symbol: C8G

Ensembl ID: ENSG00000176919

Description: complement C8 gamma chain

Associated with

Other Information

Genular Protein ID: 4175406638

Symbol: CO8G_HUMAN

Name: Complement component C8 gamma chain

UniProtKB Accession Codes:

P07360 Q14CT8 Q14CU0 Q5SQ07

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 1 CDD 1 CTD 1 ComplexPortal 1 DNASU 1 DisGeNET 1 DrugBank 4 EMBL 8 EMDB 9 Ensembl 1 EvolutionaryTrace 1 ExpressionAtlas 1 GO 12 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 5 KEGG 1 MANE-Select 1 MIM 1 MalaCards 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 Orphanet 1 OrthoDB 1 PANTHER 2 PDB 17 PDBsum 15 PIR 1 PRINTS 2 PRO 1 PROSITE 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 1 RNAct 1 Reactome 2 RefSeq 1 SIGNOR 1 SMR 1 STRING 1 SUPFAM 1 SignaLink 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 jPOST 1 neXtProt 1

Citations:

PubMed ID: 3676249

Title: The eighth component of human complement: evidence that it is an oligomeric serum protein assembled from products of three different genes.

PubMed ID: 3676249

DOI: 10.1021/bi00391a003

PubMed ID: 2447883

Title: Structural homology of human complement component C8 gamma and plasma protein HC: identity of the cysteine bond pattern.

PubMed ID: 2447883

DOI: 10.1016/0006-291x(87)90431-1

PubMed ID: 8172891

Title: Genomic structure of the human complement protein C8 gamma: homology to the lipocalin gene family.

PubMed ID: 8172891

DOI: 10.1021/bi00183a020

PubMed ID: 15164053

Title: DNA sequence and analysis of human chromosome 9.

PubMed ID: 15164053

DOI: 10.1038/nature02465

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 2446620

Title: The homology of complement factor C8 gamma chain and alpha-1-microglobulin.

PubMed ID: 2446620

DOI: 10.1016/0006-291x(87)91636-6

PubMed ID: 1707134

Title: Structural and functional characterization of complement C8 gamma, a member of the lipocalin protein family.

PubMed ID: 1707134

DOI: 10.1016/0161-5890(91)90095-2

PubMed ID: 11058761

Title: Human complement protein C8 gamma.

PubMed ID: 11058761

DOI: 10.1016/s0167-4838(00)00155-2

PubMed ID: 24275569

Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.

PubMed ID: 24275569

DOI: 10.1016/j.jprot.2013.11.014

PubMed ID: 12033936

Title: Crystal structure of human complement protein C8gamma at 1.2 A resolution reveals a lipocalin fold and a distinct ligand binding site.

PubMed ID: 12033936

DOI: 10.1021/bi025696i

PubMed ID: 17452033

Title: Structural features of the ligand binding site on human complement protein C8gamma: a member of the lipocalin family.

PubMed ID: 17452033

DOI: 10.1016/j.bbapap.2007.03.004

PubMed ID: 17692377

Title: Crystal structure of complement protein C8gamma in complex with a peptide containing the C8gamma binding site on C8alpha: implications for C8gamma ligand binding.

PubMed ID: 17692377

DOI: 10.1016/j.molimm.2007.06.359

Sequence Information:

  • Length: 202
  • Mass: 22277
  • Checksum: 4E4F73140E607FFE
  • Sequence:
    • MLPPGTATLL TLLLAAGSLG QKPQRPRRPA SPISTIQPKA NFDAQQFAGT WLLVAVGSAC 
RFLQEQGHRA EATTLHVAPQ GTAMAVSTFR KLDGICWQVR QLYGDTGVLG RFLLQARDAR 
GAVHVVVAET DYQSFAVLYL ERAGQLSVKL YARSLPVSDS VLSGFEQRVQ EAHLTEDQIF 
YFPKYGFCEA ADQFHVLDEV RR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.