Details for: DAGLA

Gene ID: 747

Symbol: DAGLA

Ensembl ID: ENSG00000134780

Description: diacylglycerol lipase alpha

Associated with

Other Information

Genular Protein ID: 1496816460

Symbol: DGLA_HUMAN

Name: Diacylglycerol lipase-alpha

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9734811

Title: Prediction of the coding sequences of unidentified human genes. X. The complete sequences of 100 new cDNA clones from brain which can code for large proteins in vitro.

PubMed ID: 9734811

DOI: 10.1093/dnares/5.3.169

PubMed ID: 12168954

Title: Construction of expression-ready cDNA clones for KIAA genes: manual curation of 330 KIAA cDNA clones.

PubMed ID: 12168954

DOI: 10.1093/dnares/9.3.99

PubMed ID: 16554811

Title: Human chromosome 11 DNA sequence and analysis including novel gene identification.

PubMed ID: 16554811

DOI: 10.1038/nature04632

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 14610053

Title: Cloning of the first sn1-DAG lipases points to the spatial and temporal regulation of endocannabinoid signaling in the brain.

PubMed ID: 14610053

DOI: 10.1083/jcb.200305129

PubMed ID: 16051747

Title: Stimulation of endocannabinoid formation in brain slice cultures through activation of group I metabotropic glutamate receptors.

PubMed ID: 16051747

DOI: 10.1124/mol.105.013961

PubMed ID: 23502535

Title: CaMKII regulates diacylglycerol lipase-alpha and striatal endocannabinoid signaling.

PubMed ID: 23502535

DOI: 10.1038/nn.3353

PubMed ID: 27595600

Title: Regulated endosomal trafficking of Diacylglycerol lipase alpha (DAGLalpha) generates distinct cellular pools; implications for endocannabinoid signaling.

PubMed ID: 27595600

DOI: 10.1016/j.mcn.2016.08.011

PubMed ID: 26668358

Title: Rapid and profound rewiring of brain lipid signaling networks by acute diacylglycerol lipase inhibition.

PubMed ID: 26668358

DOI: 10.1073/pnas.1522364112

PubMed ID: 18801880

Title: A duplication at chromosome 11q12.2-11q12.3 is associated with spinocerebellar ataxia type 20.

PubMed ID: 18801880

DOI: 10.1093/hmg/ddn283

Sequence Information:

  • Length: 1042
  • Mass: 114952
  • Checksum: A6E675984E89CB2F
  • Sequence:
  • MPGIVVFRRR WSVGSDDLVL PAIFLFLLHT TWFVILSVVL FGLVYNPHEA CSLNLVDHGR 
    GYLGILLSCM IAEMAIIWLS MRGGILYTEP RDSMQYVLYV RLAILVIEFI YAIVGIVWLT 
    QYYTSCNDLT AKNVTLGMVV CNWVVILSVC ITVLCVFDPT GRTFVKLRAT KRRQRNLRTY 
    NLRHRLEEGQ ATSWSRRLKV FLCCTRTKDS QSDAYSEIAY LFAEFFRDLD IVPSDIIAGL 
    VLLRQRQRAK RNAVLDEANN DILAFLSGMP VTRNTKYLDL KNSQEMLRYK EVCYYMLFAL 
    AAYGWPMYLM RKPACGLCQL ARSCSCCLCP ARPRFAPGVT IEEDNCCGCN AIAIRRHFLD 
    ENMTAVDIVY TSCHDAVYET PFYVAVDHDK KKVVISIRGT LSPKDALTDL TGDAERLPVE 
    GHHGTWLGHK GMVLSAEYIK KKLEQEMVLS QAFGRDLGRG TKHYGLIVVG HSLGAGTAAI 
    LSFLLRPQYP TLKCFAYSPP GGLLSEDAME YSKEFVTAVV LGKDLVPRIG LSQLEGFRRQ 
    LLDVLQRSTK PKWRIIVGAT KCIPKSELPE EVEVTTLAST RLWTHPSDLT IALSASTPLY 
    PPGRIIHVVH NHPAEQCCCC EQEEPTYFAI WGDNKAFNEV IISPAMLHEH LPYVVMEGLN 
    KVLENYNKGK TALLSAAKVM VSPTEVDLTP ELIFQQQPLP TGPPMPTGLA LELPTADHRN 
    SSVRSKSQSE MSLEGFSEGR LLSPVVAAAA RQDPVELLLL STQERLAAEL QARRAPLATM 
    ESLSDTESLY SFDSRRSSGF RSIRGSPSLH AVLERDEGHL FYIDPAIPEE NPSLSSRTEL 
    LAADSLSKHS QDTQPLEAAL GSGGVTPERP PSAAANDEEE EVGGGGGGPA SRGELALHNG 
    RLGDSPSPQV LEFAEFIDSL FNLDSKSSSF QDLYCMVVPE SPTSDYAEGP KSPSQQEILL 
    RAQFEPNLVP KPPRLFAGSA DPSSGISLSP SFPLSSSGEL MDLTPTGLSS QECLAADKIR 
    TSTPTGHGAS PAKQDELVIS AR

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.