Details for: FMNL1
Associated with
Cells (max top 100)
(Cell Significance Index and respective Thresholds are uniquely calculated using our advanced thresholding algorithms to reveal cell-specific gene markers)
- Cell Name: polychromatophilic erythroblast (CL0000550)
Fold Change: 110.0645
Cell Significance Index: -17.1200 - Cell Name: mucosal type mast cell (CL0000485)
Fold Change: 51.6668
Cell Significance Index: -20.9900 - Cell Name: hematopoietic oligopotent progenitor cell (CL0002032)
Fold Change: 46.5220
Cell Significance Index: -11.8000 - Cell Name: peripheral blood mononuclear cell (CL2000001)
Fold Change: 44.3053
Cell Significance Index: -22.7900 - Cell Name: ileal goblet cell (CL1000326)
Fold Change: 30.5877
Cell Significance Index: -20.5300 - Cell Name: orthochromatic erythroblast (CL0000552)
Fold Change: 13.9664
Cell Significance Index: -17.2200 - Cell Name: CD8-alpha-beta-positive, alpha-beta intraepithelial T cell (CL0000796)
Fold Change: 5.5135
Cell Significance Index: -14.7700 - Cell Name: epidermal Langerhans cell (CL0002457)
Fold Change: 4.8250
Cell Significance Index: -10.5600 - Cell Name: CD8-positive, alpha-beta regulatory T cell (CL0000795)
Fold Change: 4.7583
Cell Significance Index: -14.6200 - Cell Name: CD14-positive, CD16-negative classical monocyte (CL0002057)
Fold Change: 4.4680
Cell Significance Index: 82.5800 - Cell Name: stromal cell of bone marrow (CL0010001)
Fold Change: 4.4551
Cell Significance Index: -17.5800 - Cell Name: hepatic pit cell (CL2000054)
Fold Change: 3.5500
Cell Significance Index: 9.5100 - Cell Name: early pro-B cell (CL0002046)
Fold Change: 2.5248
Cell Significance Index: 162.8900 - Cell Name: IgG-negative class switched memory B cell (CL0002117)
Fold Change: 1.9678
Cell Significance Index: 8.8000 - Cell Name: late promyelocyte (CL0002151)
Fold Change: 1.2692
Cell Significance Index: 8.4200 - Cell Name: paneth cell of epithelium of small intestine (CL1000343)
Fold Change: 0.9218
Cell Significance Index: 19.9700 - Cell Name: neutrophil progenitor cell (CL0000834)
Fold Change: 0.7748
Cell Significance Index: 20.7300 - Cell Name: CD4-positive, alpha-beta memory T cell, CD45RO-positive (CL0001204)
Fold Change: 0.6304
Cell Significance Index: 18.5200 - Cell Name: decidual cell (CL2000002)
Fold Change: 0.6277
Cell Significance Index: 10.0700 - Cell Name: granulosa cell (CL0000501)
Fold Change: 0.4883
Cell Significance Index: 12.8400 - Cell Name: enteroendocrine cell of colon (CL0009042)
Fold Change: 0.4722
Cell Significance Index: 89.8600 - Cell Name: monocyte-derived dendritic cell (CL0011031)
Fold Change: 0.4238
Cell Significance Index: 7.2800 - Cell Name: GABAergic interneuron (CL0011005)
Fold Change: 0.3700
Cell Significance Index: 255.9400 - Cell Name: IgG memory B cell (CL0000979)
Fold Change: 0.3610
Cell Significance Index: 2.1800 - Cell Name: L2/3-6 intratelencephalic projecting glutamatergic neuron (CL4023040)
Fold Change: 0.3259
Cell Significance Index: 65.3700 - Cell Name: colon goblet cell (CL0009039)
Fold Change: 0.3090
Cell Significance Index: 30.5700 - Cell Name: tonsil germinal center B cell (CL2000006)
Fold Change: 0.2497
Cell Significance Index: 29.4500 - Cell Name: tuft cell of colon (CL0009041)
Fold Change: 0.2385
Cell Significance Index: 215.3100 - Cell Name: epithelial cell of small intestine (CL0002254)
Fold Change: 0.1417
Cell Significance Index: 23.0500 - Cell Name: obsolete caudal ganglionic eminence derived GABAergic cortical interneuron (CL4023070)
Fold Change: 0.1280
Cell Significance Index: 45.9100 - Cell Name: hippocampal granule cell (CL0001033)
Fold Change: 0.0938
Cell Significance Index: 6.3100 - Cell Name: intestinal crypt stem cell of colon (CL0009043)
Fold Change: 0.0455
Cell Significance Index: 4.9500 - Cell Name: hair follicular keratinocyte (CL2000092)
Fold Change: 0.0295
Cell Significance Index: 13.0300 - Cell Name: pigmented epithelial cell (CL0000529)
Fold Change: -0.0046
Cell Significance Index: -8.6900 - Cell Name: anterior lens cell (CL0002223)
Fold Change: -0.0064
Cell Significance Index: -11.7200 - Cell Name: lens epithelial cell (CL0002224)
Fold Change: -0.0074
Cell Significance Index: -11.3300 - Cell Name: hippocampal pyramidal neuron (CL1001571)
Fold Change: -0.0116
Cell Significance Index: -0.3300 - Cell Name: small intestine goblet cell (CL1000495)
Fold Change: -0.0131
Cell Significance Index: -0.4600 - Cell Name: enterocyte of epithelium of small intestine (CL1000334)
Fold Change: -0.0135
Cell Significance Index: -0.3900 - Cell Name: secondary lens fiber (CL0002225)
Fold Change: -0.0135
Cell Significance Index: -18.3000 - Cell Name: cell in vitro (CL0001034)
Fold Change: -0.0163
Cell Significance Index: -8.9200 - Cell Name: pulmonary alveolar epithelial cell (CL0000322)
Fold Change: -0.0213
Cell Significance Index: -16.0900 - Cell Name: pancreatic A cell (CL0000171)
Fold Change: -0.0256
Cell Significance Index: -19.0000 - Cell Name: non-pigmented ciliary epithelial cell (CL0002304)
Fold Change: -0.0279
Cell Significance Index: -17.7300 - Cell Name: kidney loop of Henle cortical thick ascending limb epithelial cell (CL1001109)
Fold Change: -0.0309
Cell Significance Index: -22.6600 - Cell Name: type B pancreatic cell (CL0000169)
Fold Change: -0.0338
Cell Significance Index: -19.0700 - Cell Name: pancreatic PP cell (CL0002275)
Fold Change: -0.0347
Cell Significance Index: -21.6600 - Cell Name: enteroendocrine cell of small intestine (CL0009006)
Fold Change: -0.0376
Cell Significance Index: -0.9400 - Cell Name: ciliary muscle cell (CL1000443)
Fold Change: -0.0458
Cell Significance Index: -20.8000 - Cell Name: abnormal cell (CL0001061)
Fold Change: -0.0482
Cell Significance Index: -4.9200 - Cell Name: dopaminergic neuron (CL0000700)
Fold Change: -0.0511
Cell Significance Index: -14.7000 - Cell Name: stromal cell of ovary (CL0002132)
Fold Change: -0.0511
Cell Significance Index: -7.0200 - Cell Name: enterocyte of epithelium of large intestine (CL0002071)
Fold Change: -0.0622
Cell Significance Index: -2.8200 - Cell Name: microfold cell of epithelium of small intestine (CL1000353)
Fold Change: -0.0651
Cell Significance Index: -4.5000 - Cell Name: intermediate cell of urothelium (CL4030055)
Fold Change: -0.0714
Cell Significance Index: -12.8800 - Cell Name: indirect pathway medium spiny neuron (CL4023029)
Fold Change: -0.0726
Cell Significance Index: -3.2100 - Cell Name: neoplastic cell (CL0001063)
Fold Change: -0.0728
Cell Significance Index: -14.4500 - Cell Name: gut absorptive cell (CL0000677)
Fold Change: -0.0948
Cell Significance Index: -5.6900 - Cell Name: pancreatic D cell (CL0000173)
Fold Change: -0.0982
Cell Significance Index: -20.6800 - Cell Name: odontoblast (CL0000060)
Fold Change: -0.1036
Cell Significance Index: -13.2800 - Cell Name: direct pathway medium spiny neuron (CL4023026)
Fold Change: -0.1046
Cell Significance Index: -3.9600 - Cell Name: pro-T cell (CL0000827)
Fold Change: -0.1116
Cell Significance Index: -2.8500 - Cell Name: pancreatic acinar cell (CL0002064)
Fold Change: -0.1125
Cell Significance Index: -19.2100 - Cell Name: glycinergic neuron (CL1001509)
Fold Change: -0.1156
Cell Significance Index: -6.0700 - Cell Name: cardiac muscle myoblast (CL0000513)
Fold Change: -0.1170
Cell Significance Index: -8.9800 - Cell Name: intestinal tuft cell (CL0019032)
Fold Change: -0.1199
Cell Significance Index: -7.3500 - Cell Name: CD4-positive, alpha-beta thymocyte (CL0000810)
Fold Change: -0.1305
Cell Significance Index: -2.2500 - Cell Name: epithelial cell of stomach (CL0002178)
Fold Change: -0.1310
Cell Significance Index: -15.2700 - Cell Name: lactocyte (CL0002325)
Fold Change: -0.1317
Cell Significance Index: -17.0200 - Cell Name: basal cell of urothelium (CL1000486)
Fold Change: -0.1323
Cell Significance Index: -16.2700 - Cell Name: pigmented ciliary epithelial cell (CL0002303)
Fold Change: -0.1358
Cell Significance Index: -19.7500 - Cell Name: luminal adaptive secretory precursor cell of mammary gland (CL4033057)
Fold Change: -0.1371
Cell Significance Index: -6.4500 - Cell Name: eukaryotic cell (CL0000255)
Fold Change: -0.1449
Cell Significance Index: -6.3000 - Cell Name: pancreatic ductal cell (CL0002079)
Fold Change: -0.1465
Cell Significance Index: -16.7800 - Cell Name: smooth muscle cell of sphincter of pupil (CL0002243)
Fold Change: -0.1571
Cell Significance Index: -16.3600 - Cell Name: forebrain neuroblast (CL1000042)
Fold Change: -0.1615
Cell Significance Index: -9.9300 - Cell Name: transit amplifying cell of small intestine (CL0009012)
Fold Change: -0.1890
Cell Significance Index: -3.9200 - Cell Name: sebum secreting cell (CL0000317)
Fold Change: -0.2070
Cell Significance Index: -14.6400 - Cell Name: intestinal crypt stem cell of small intestine (CL0009017)
Fold Change: -0.2127
Cell Significance Index: -4.5300 - Cell Name: acinar cell of salivary gland (CL0002623)
Fold Change: -0.2209
Cell Significance Index: -10.3000 - Cell Name: early promyelocyte (CL0002154)
Fold Change: -0.2256
Cell Significance Index: -1.4400 - Cell Name: medial ganglionic eminence derived interneuron (CL4023063)
Fold Change: -0.2318
Cell Significance Index: -3.3200 - Cell Name: hematopoietic cell (CL0000988)
Fold Change: -0.2332
Cell Significance Index: -3.4100 - Cell Name: preadipocyte (CL0002334)
Fold Change: -0.2582
Cell Significance Index: -5.0400 - Cell Name: progenitor cell of mammary luminal epithelium (CL0009116)
Fold Change: -0.2679
Cell Significance Index: -19.9700 - Cell Name: bladder urothelial cell (CL1001428)
Fold Change: -0.2957
Cell Significance Index: -15.3600 - Cell Name: cerebellar granule cell (CL0001031)
Fold Change: -0.3075
Cell Significance Index: -5.2700 - Cell Name: corticothalamic-projecting glutamatergic cortical neuron (CL4023013)
Fold Change: -0.3127
Cell Significance Index: -9.9600 - Cell Name: eye photoreceptor cell (CL0000287)
Fold Change: -0.3183
Cell Significance Index: -20.0600 - Cell Name: retinal progenitor cell (CL0002672)
Fold Change: -0.3208
Cell Significance Index: -18.0000 - Cell Name: transit amplifying cell of colon (CL0009011)
Fold Change: -0.3213
Cell Significance Index: -10.2900 - Cell Name: L6b glutamatergic cortical neuron (CL4023038)
Fold Change: -0.3238
Cell Significance Index: -10.6000 - Cell Name: L5 extratelencephalic projecting glutamatergic cortical neuron (CL4023041)
Fold Change: -0.3523
Cell Significance Index: -12.3400 - Cell Name: DN3 thymocyte (CL0000807)
Fold Change: -0.3570
Cell Significance Index: -3.5800 - Cell Name: lung endothelial cell (CL1001567)
Fold Change: -0.3627
Cell Significance Index: -18.8900 - Cell Name: pvalb GABAergic cortical interneuron (CL4023018)
Fold Change: -0.3788
Cell Significance Index: -8.0400 - Cell Name: lymphoid lineage restricted progenitor cell (CL0000838)
Fold Change: -0.3896
Cell Significance Index: -4.9400 - Cell Name: leukocyte (CL0000738)
Fold Change: -0.3988
Cell Significance Index: -6.7700 - Cell Name: fibro/adipogenic progenitor cell (CL0009099)
Fold Change: -0.4226
Cell Significance Index: -21.3600 - Cell Name: CD14-positive monocyte (CL0001054)
Fold Change: -0.4296
Cell Significance Index: -8.4000
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Other Information
Genular Protein ID: 1026472126
Symbol: FMNL1_HUMAN
Name: Formin-like protein 1
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 16625196
Title: DNA sequence of human chromosome 17 and analysis of rearrangement in the human lineage.
PubMed ID: 16625196
DOI: 10.1038/nature04689
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 9799091
Title: The NIK protein kinase and C17orf1 genes: chromosomal mapping, gene structures and mutational screening in frontotemporal dementia and parkinsonism linked to chromosome 17.
PubMed ID: 9799091
PubMed ID: 19815554
Title: Formin-like 1 (FMNL1) is regulated by N-terminal myristoylation and induces polarized membrane blebbing.
PubMed ID: 19815554
PubMed ID: 17081983
Title: Global, in vivo, and site-specific phosphorylation dynamics in signaling networks.
PubMed ID: 17081983
PubMed ID: 19367720
Title: Phosphorylation analysis of primary human T lymphocytes using sequential IMAC and titanium oxide enrichment.
PubMed ID: 19367720
DOI: 10.1021/pr800500r
PubMed ID: 18669648
Title: A quantitative atlas of mitotic phosphorylation.
PubMed ID: 18669648
PubMed ID: 19690332
Title: Quantitative phosphoproteomic analysis of T cell receptor signaling reveals system-wide modulation of protein-protein interactions.
PubMed ID: 19690332
PubMed ID: 20068231
Title: Quantitative phosphoproteomics reveals widespread full phosphorylation site occupancy during mitosis.
PubMed ID: 20068231
PubMed ID: 21834987
Title: Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration.
PubMed ID: 21834987
PubMed ID: 21269460
Title: Initial characterization of the human central proteome.
PubMed ID: 21269460
PubMed ID: 21148482
PubMed ID: 23186163
Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.
PubMed ID: 23186163
DOI: 10.1021/pr300630k
PubMed ID: 24275569
Title: An enzyme assisted RP-RPLC approach for in-depth analysis of human liver phosphoproteome.
PubMed ID: 24275569
PubMed ID: 25255805
Title: Global profiling of co- and post-translationally N-myristoylated proteomes in human cells.
PubMed ID: 25255805
DOI: 10.1038/ncomms5919
PubMed ID: 25944712
Title: N-terminome analysis of the human mitochondrial proteome.
PubMed ID: 25944712
Sequence Information:
- Length: 1100
- Mass: 121854
- Checksum: 91F9CE2B3B526FFC
- Sequence:
MGNAAGSAEQ PAGPAAPPPK QPAPPKQPMP AAGELEERFN RALNCMNLPP DKVQLLSQYD NEKKWELICD QERFQVKNPP AAYIQKLKSY VDTGGVSRKV AADWMSNLGF KRRVQESTQV LRELETSLRT NHIGWVQEFL NEENRGLDVL LEYLAFAQCS VTYDMESTDN GASNSEKNKP LEQSVEDLSK GPPSSVPKSR HLTIKLTPAH SRKALRNSRI VSQKDDVHVC IMCLRAIMNY QSGFSLVMNH PACVNEIALS LNNKNPRTKA LVLELLAAVC LVRGGHDIIL AAFDNFKEVC GEQHRFEKLM EYFRNEDSNI DFMVACMQFI NIVVHSVENM NFRVFLQYEF THLGLDLYLE RLRLTESDKL QVQIQAYLDN IFDVGALLED TETKNAVLEH MEELQEQVAL LTERLRDAEN ESMAKIAELE KQLSQARKEL ETLRERFSES TAMGPSRRPP EPEKAPPAAP TRPSALELKV EELEEKGLIR ILRGPGDAVS IEILPVAVAT PSGGDAPTPG VPTGSPSPDL APAAEPAPGA APPPPPPLPG LPSPQEAPPS APPQAPPLPG SPEPPPAPPL PGDLPPPPPP PPPPPGTDGP VPPPPPPPPP PPGGPPDALG RRDSELGPGV KAKKPIQTKF RMPLLNWVAL KPSQITGTVF TELNDEKVLQ ELDMSDFEEQ FKTKSQGPSL DLSALKSKAA QKAPSKATLI EANRAKNLAI TLRKGNLGAE RICQAIEAYD LQALGLDFLE LLMRFLPTEY ERSLITRFER EQRPMEELSE EDRFMLCFSR IPRLPERMTT LTFLGNFPDT AQLLMPQLNA IIAASMSIKS SDKLRQILEI VLAFGNYMNS SKRGAAYGFR LQSLDALLEM KSTDRKQTLL HYLVKVIAEK YPQLTGFHSD LHFLDKAGSV SLDSVLADVR SLQRGLELTQ REFVRQDDCM VLKEFLRANS PTMDKLLADS KTAQEAFESV VEYFGENPKT TSPGLFFSLF SRFIKAYKKA EQEVEQWKKE AAAQEAGADT PGKGEPPAPK SPPKARRPQM DLISELKRRQ QKEPLIYESD RDGAIEDIIT VIKTVPFTAR TGKRTSRLLC EASLGEEMPL
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.