Details for: LDLRAD4

Gene ID: 753

Symbol: LDLRAD4

Ensembl ID: ENSG00000168675

Description: low density lipoprotein receptor class A domain containing 4

Associated with

  • Early endosome membrane
    (GO:0031901)
  • Golgi membrane
    (GO:0000139)
  • Intracellular membrane-bounded organelle
    (GO:0043231)
  • Membrane
    (GO:0016020)
  • Negative regulation of cell migration
    (GO:0030336)
  • Negative regulation of epithelial to mesenchymal transition
    (GO:0010719)
  • Negative regulation of smad protein signal transduction
    (GO:0060392)
  • Negative regulation of transforming growth factor beta receptor signaling pathway
    (GO:0030512)
  • R-smad binding
    (GO:0070412)

Other Information

Genular Protein ID: 322412053

Symbol: LRAD4_HUMAN

Name: Low-density lipoprotein receptor class A domain-containing protein 4

UniProtKB Accession Codes:

O15165 B3KNT9 E9PAY9 K7EN38 O15166 O15167 O15168 Q5U646 Q6NXP3

Database IDs:

AGR 1 AlphaFoldDB 1 Antibodypedia 1 Bgee 1 BioGRID 1 BioGRID-ORCS 1 BioMuta 1 CCDS 5 CDD 1 CTD 1 ChiTaRS 1 DNASU 1 DisGeNET 1 EMBL 14 Ensembl 8 ExpressionAtlas 1 GO 9 Gene3D 1 GeneCards 1 GeneTree 1 Genevisible 1 GenomeRNAi 1 HGNC 1 HOGENOM 1 HPA 1 InParanoid 1 IntAct 1 InterPro 4 KEGG 1 MANE-Select 1 MIM 1 MassIVE 1 NCBI Taxonomy 1 OMA 1 OpenTargets 1 OrthoDB 1 PANTHER 2 PRO 1 PROSITE 2 PROSITE-ProRule 1 PathwayCommons 1 PaxDb 1 PeptideAtlas 1 Pfam 1 PharmGKB 1 Pharos 1 PhosphoSitePlus 1 PhylomeDB 1 Proteomes 1 ProteomicsDB 7 RNAct 1 RefSeq 17 SAM 1 SMART 1 STRING 1 SUPFAM 1 SignaLink 1 SwissPalm 1 TreeFam 1 UCSC 1 VEuPathDB 1 eggNOG 1 iPTMnet 1 neXtProt 1

Citations:

PubMed ID: 9479497

Title: Multiple transcriptional variants and RNA editing in C18orf1, a novel gene with LDLRA and transmembrane domains on 18p11.2.

PubMed ID: 9479497

DOI: 10.1006/geno.1997.5118

PubMed ID: 14702039

Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.

PubMed ID: 14702039

DOI: 10.1038/ng1285

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 19461657

Title: Analysis of a t(18;21)(p11.1;p11.1) translocation in a family with schizophrenia.

PubMed ID: 19461657

DOI: 10.1038/jhg.2009.47

PubMed ID: 24627487

Title: C18 ORF1, a novel negative regulator of transforming growth factor-beta signaling.

PubMed ID: 24627487

DOI: 10.1074/jbc.m114.558981

Sequence Information:

  • Length: 306
  • Mass: 33900
  • Checksum: F48EF66E329201BD
  • Sequence:
    • MPEAGFQATN AFTECKFTCT SGKCLYLGSL VCNQQNDCGD NSDEENCLLV TEHPPPGIFN 
SELEFAQIII IVVVVTVMVV VIVCLLNHYK VSTRSFINRP NQSRRREDGL PQEGCLWPSD 
SAAPRLGASE IMHAPRSRDR FTAPSFIQRD RFSRFQPTYP YVQHEIDLPP TISLSDGEEP 
PPYQGPCTLQ LRDPEQQMEL NRESVRAPPN RTIFDSDLID IAMYSGGPCP PSSNSGISAS 
TCSSNGRMEG PPPTYSEVMG HHPGASFLHH QRSNAHRGSR LQFQQNNAES TIVPIKGKDR 
KPGNLV

Genular Protein ID: 3137062394

Symbol: A8K6A9_HUMAN

Name: N/A

UniProtKB Accession Codes:

A8K6A9

Database IDs:

ARBA 9 AlphaFoldDB 1 BioGRID-ORCS 1 CTD 1 DNASU 1 EMBL 2 GO 3 GenomeRNAi 1 InterPro 1 NCBI Taxonomy 1 PANTHER 2 PeptideAtlas 1 RefSeq 1 SAM 1

Sequence Information:

  • Length: 229
  • Mass: 25629
  • Checksum: D124C6E2402A031E
  • Sequence:
    • MVVVIVCLLN HYKVSTRSFI NRPNQSRRRE DGLPQEGCLW PSDSAAPRLG ASEIMHAPRS 
RDRFTAPSFI QRDRFSRFQP TYPYVQHEID LPPTISLSDG EEPPPYQGPC TLQLRDPEQQ 
MELNRESVRA PPNRTIFDSD LIDIAMYSGG PCPPSSNSGI SASTCSSNGR MEGPPPTYSE 
VMGHHPGASF LHHQRSNAHR GRRLQFQQNN AESTIVPIKG KDRKPGNLV

Genular Protein ID: 2377798016

Symbol: A0A7I2V575_HUMAN

Name: N/A

UniProtKB Accession Codes:

A0A7I2V575

Database IDs:

ARBA 9 Bgee 1 CTD 1 EMBL 4 Ensembl 4 GO 4 GeneTree 1 HGNC 1 InterPro 1 MaxQB 1 NCBI Taxonomy 1 PANTHER 2 PeptideAtlas 1 Proteomes 2 RefSeq 3 SAM 2

Citations:

PubMed ID: 16177791

Title: DNA sequence and analysis of human chromosome 18.

PubMed ID: 16177791

DOI: 10.1038/nature03983

Sequence Information:

  • Length: 259
  • Mass: 28764
  • Checksum: A53C0A337FE0737C
  • Sequence:
    • MPEAGFQATN AFTAELEFAQ IIIIVVVVTV MVVVIVCLLN HYKVSTRSFI NRPNQSRRRE 
DGLPQEGCLW PSDSAAPRLG ASEIMHAPRS RDRFTAPSFI QRDRFSRFQP TYPYVQHEID 
LPPTISLSDG EEPPPYQGPC TLQLRDPEQQ MELNRESVRA PPNRTIFDSD LIDIAMYSGG 
PCPPSSNSGI SASTCSSNGR MEGPPPTYSE VMGHHPGASF LHHQRSNAHR GSRLQFQQNN 
AESTIVPIKG KDRKPGNLV

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.