Details for: CFAP410

Gene ID: 755

Symbol: CFAP410

Ensembl ID: ENSG00000160226

Description: cilia and flagella associated protein 410

Associated with

Other Information

Genular Protein ID: 1028751522

Symbol: CF410_HUMAN

Name: C21orf-HUMF09G8.5

UniProtKB Accession Codes:

Database IDs:

Citations:

PubMed ID: 9465297

Title: Characterization of a novel gene, C21orf2, on human chromosome 21q22.3 and its exclusion as the APECED gene by mutation analysis.

PubMed ID: 9465297

DOI: 10.1006/geno.1997.5066

PubMed ID: 10830953

Title: The DNA sequence of human chromosome 21.

PubMed ID: 10830953

DOI: 10.1038/35012518

PubMed ID: 15489334

Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).

PubMed ID: 15489334

DOI: 10.1101/gr.2596504

PubMed ID: 9325172

Title: Immunochemical characterization of a novel mitochondrially located protein encoded by a nuclear gene within the DFNB8/10 critical region on 21q22.3.

PubMed ID: 9325172

DOI: 10.1006/bbrc.1997.7352

PubMed ID: 19369195

Title: Large-scale proteomics analysis of the human kinome.

PubMed ID: 19369195

DOI: 10.1074/mcp.m800588-mcp200

PubMed ID: 21834987

Title: Identification and characterization of a set of conserved and new regulators of cytoskeletal organisation, cell morphology and migration.

PubMed ID: 21834987

DOI: 10.1186/1741-7007-9-54

PubMed ID: 23186163

Title: Toward a comprehensive characterization of a human cancer cell phosphoproteome.

PubMed ID: 23186163

DOI: 10.1021/pr300630k

PubMed ID: 26290490

Title: The NEK1 interactor, C21ORF2, is required for efficient DNA damage repair.

PubMed ID: 26290490

DOI: 10.1093/abbs/gmv076

PubMed ID: 26294103

Title: C21orf2 is mutated in recessive early-onset retinal dystrophy with macular staphyloma and encodes a protein that localises to the photoreceptor primary cilium.

PubMed ID: 26294103

DOI: 10.1136/bjophthalmol-2015-307277

PubMed ID: 26167768

Title: An siRNA-based functional genomics screen for the identification of regulators of ciliogenesis and ciliopathy genes.

PubMed ID: 26167768

DOI: 10.1038/ncb3201

PubMed ID: 27548899

Title: Identification of novel mutations in the LRR-Cap domain of C21orf2 in Japanese patients with retinitis pigmentosa and Cone-Rod Dystrophy.

PubMed ID: 27548899

DOI: 10.1167/iovs.16-19450

PubMed ID: 26974433

Title: Axial spondylometaphyseal dysplasia is caused by C21orf2 mutations.

PubMed ID: 26974433

DOI: 10.1371/journal.pone.0150555

PubMed ID: 28422394

Title: Homozygous variant in C21orf2 in a case of Jeune syndrome with severe thoracic involvement: Extending the phenotypic spectrum.

PubMed ID: 28422394

DOI: 10.1002/ajmg.a.38215

Sequence Information:

  • Length: 256
  • Mass: 28340
  • Checksum: D33F31EDAEA77D2A
  • Sequence:
  • MKLTRKMVLT RAKASELHSV RKLNCWGSRL TDISICQEMP SLEVITLSVN SISTLEPVSR 
    CQRLSELYLR RNRIPSLAEL FYLKGLPRLR VLWLAENPCC GTSPHRYRMT VLRTLPRLQK 
    LDNQAVTEEE LSRALSEGEE ITAAPEREGT GHGGPKLCCT LSSLSSAAET GRDPLDSEEE 
    ATSGAQDERG LKPPSRGQFP SLSARDASSS HRGRNVLTAI LLLLRELDAE GLEAVQQTVG 
    SRLQALRGEE VQEHAE

Database document:

This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.