Details for: TMEM50B
Associated with
Significant Cells
Cell Significance Index (CSI) scores for the chosen context(s)
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CSI 14.33rCSI 34.16%PRS 43.38
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CSI 13.72rCSI 36.68%PRS 34.61
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CSI 11.71rCSI 14.26%PRS 48.15
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CSI 11.52rCSI 9.55%PRS 39.42
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CSI 7.76rCSI 11.87%PRS 56.99
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CSI 6.96rCSI 15.8%PRS 46.47
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CSI 6.14rCSI 6.73%PRS 44.64
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CSI 5.49rCSI 8.44%PRS 47.37
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CSI 5.26rCSI 13.3%PRS 48.83
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CSI 4.8rCSI 8.47%PRS 25.74
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CSI 4.76rCSI 21.14%PRS 39.5
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CSI 4.41rCSI 27.56%PRS 34.07
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CSI 3.82rCSI 2.65%PRS 48.78
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CSI 3.79rCSI 3.5%PRS 41.85
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CSI 3.78rCSI 2.88%PRS 51.47
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CSI 3.61rCSI 3.33%PRS 61.09
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CSI 3.59rCSI 9.48%PRS 48
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CSI 3.57rCSI 8.01%PRS 27.27
-
CSI 3.48rCSI 2.79%PRS 61.94
-
CSI 3.46rCSI 8.98%PRS 46.32
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CSI 3.4rCSI 4.08%PRS 39.09
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CSI 3.23rCSI 7.38%PRS 40.31
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CSI 3.21rCSI 2.55%PRS 62.3
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CSI 3.08rCSI 3.72%PRS 47.99
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CSI 3.07rCSI 9.88%PRS 40.41
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CSI 3.02rCSI 5.22%PRS 32.41
-
CSI 2.96rCSI 2.45%PRS 41.7
-
CSI 2.88rCSI 3.01%PRS 41.44
-
CSI 2.84rCSI 4.16%PRS 43.63
-
CSI 2.76rCSI 8.64%PRS 27.77
-
CSI 2.53rCSI 14.51%PRS 51.67
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CSI 2.47rCSI 3.64%PRS 37.55
-
CSI 2.42rCSI 3.31%PRS 45.4
-
CSI 2.42rCSI 4.66%PRS 70.41
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CSI 2.4rCSI 4.29%PRS 39.41
-
CSI 2.39rCSI 1.67%PRS 53.12
-
CSI 2.38rCSI 2.34%PRS 55.67
-
CSI 2.37rCSI 2.08%PRS 45.52
-
CSI 2.35rCSI 2.5%PRS 56.18
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CSI 2.34rCSI 11.19%PRS 39.41
-
CSI 2.28rCSI 3.39%PRS 43.84
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CSI 2.28rCSI 9.29%PRS 39.12
-
CSI 2.23rCSI 9.62%PRS 57.64
-
CSI 2.2rCSI 1.65%PRS 54.91
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CSI 2.19rCSI 1.62%PRS 35.21
-
CSI 2.17rCSI 1.28%PRS 54.75
-
CSI 2.14rCSI 5.31%PRS 39.05
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CSI 2.1rCSI 10.55%PRS 51.23
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CSI 2.09rCSI 1.57%PRS 43.81
-
CSI 2.09rCSI 1.5%PRS 52.96
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CSI 2.08rCSI 3.17%PRS 45.29
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CSI 2.07rCSI 1.68%PRS 41.83
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CSI 2.06rCSI 3.28%PRS 50.84
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CSI 2.05rCSI 3.7%PRS 67.86
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CSI 2.04rCSI 1.71%PRS 57.74
-
CSI 2.03rCSI 2.88%PRS 38.16
-
CSI 2.03rCSI 2.81%PRS 46.48
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CSI 2.02rCSI 1.7%PRS 45.93
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CSI 2.02rCSI 1.94%PRS 32.22
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CSI 1.98rCSI 2.31%PRS 55.57
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CSI 1.96rCSI 1.77%PRS 37.61
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CSI 1.93rCSI 3.67%PRS 57.4
-
CSI 1.92rCSI 7.18%PRS 34.83
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CSI 1.91rCSI 1.48%PRS 56.94
-
CSI 1.89rCSI 6.85%PRS 59.6
-
CSI 1.89rCSI 1.78%PRS 42.09
-
CSI 1.88rCSI 2.87%PRS 49.57
-
CSI 1.88rCSI 1.65%PRS 31.02
-
CSI 1.85rCSI 2.95%PRS 35.29
-
CSI 1.84rCSI 2.53%PRS 61.13
-
CSI 1.84rCSI 3.7%PRS 31.63
-
CSI 1.84rCSI 3.81%PRS 39.14
-
CSI 1.83rCSI 1.6%PRS 50.22
-
CSI 1.81rCSI 1.2%PRS 44.9
-
CSI 1.78rCSI 1.72%PRS 41.46
-
CSI 1.78rCSI 1.37%PRS 39.41
-
CSI 1.78rCSI 2.55%PRS 48.32
-
CSI 1.77rCSI 3.91%PRS 44.65
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CSI 1.76rCSI 3.19%PRS 35.22
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CSI 1.74rCSI 2.81%PRS 32.47
-
CSI 1.73rCSI 1.77%PRS 59.47
-
CSI 1.69rCSI 2.1%PRS 43.51
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CSI 1.66rCSI 2.37%PRS 43.66
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CSI 1.64rCSI 2.25%PRS 37.95
-
CSI 1.64rCSI 2.07%PRS 53.98
-
CSI 1.64rCSI 1.24%PRS 52.55
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CSI 1.63rCSI 1.28%PRS 46.92
-
CSI 1.61rCSI 1.08%PRS 50.34
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CSI 1.6rCSI 2.44%PRS 41.42
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CSI 1.59rCSI 1.7%PRS 38.82
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CSI 1.58rCSI 2.59%PRS 32.47
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CSI 1.56rCSI 2.52%PRS 50.27
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CSI 1.56rCSI 1.99%PRS 45.83
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CSI 1.56rCSI 3.56%PRS 35.09
-
CSI 1.56rCSI 2.53%PRS 39.62
-
CSI 1.56rCSI 2.35%PRS 42.55
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CSI 1.54rCSI 1.84%PRS 59.71
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CSI 1.53rCSI 3.64%PRS 46.74
-
CSI 1.51rCSI 1.8%PRS 60.72
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CSI 1.5rCSI 1.93%PRS 27.55
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CSI 0.2rCSI 1.0%PRS 52.9%
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CSI 0.2rCSI 4.3%PRS 34.3%
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CSI 0.2rCSI 1.6%PRS 29.9%
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CSI 0.2rCSI 0.8%PRS 51.0%
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CSI 0.3rCSI 2.9%PRS 57.8%
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CSI 0.3rCSI 2.2%PRS 58.1%
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CSI 0.3rCSI 1.6%PRS 64.1%
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CSI 0.3rCSI 2.5%PRS 73.5%
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CSI 0.3rCSI 6.0%PRS 67.2%
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CSI 0.3rCSI 1.3%PRS 27.5%
-
CSI 0.3rCSI 2.0%PRS 27.9%
-
CSI 0.4rCSI 0.9%PRS 25.9%
-
CSI 0.4rCSI 4.3%PRS 74.8%
-
CSI 0.4rCSI 2.3%PRS 55.9%
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CSI 0.4rCSI 4.7%PRS 61.8%
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CSI 0.4rCSI 3.0%PRS 59.7%
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CSI 0.4rCSI 1.3%PRS 43.4%
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CSI 0.5rCSI 1.3%PRS 33.2%
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CSI 0.5rCSI 1.6%PRS 25.6%
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CSI 0.5rCSI 2.2%PRS 52.1%
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CSI 0.5rCSI 1.2%PRS 37.5%
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CSI 0.5rCSI 2.0%PRS 59.9%
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CSI 0.5rCSI 2.1%PRS 35.4%
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CSI 0.6rCSI 1.2%PRS 30.4%
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CSI 0.6rCSI 3.2%PRS 50.6%
-
CSI 0.6rCSI 2.7%PRS 38.6%
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CSI 0.6rCSI 3.4%PRS 56.7%
-
CSI 0.6rCSI 3.0%PRS 64.4%
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CSI 0.7rCSI 2.1%PRS 29.8%
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CSI 0.7rCSI 1.5%PRS 39.8%
-
CSI 0.7rCSI 2.2%PRS 48.9%
-
CSI 0.7rCSI 1.9%PRS 49.7%
-
CSI 0.7rCSI 2.3%PRS 38.1%
-
CSI 0.7rCSI 1.4%PRS 63.9%
-
CSI 0.7rCSI 0.9%PRS 51.7%
-
CSI 0.7rCSI 0.8%PRS 46.6%
-
CSI 0.8rCSI 4.2%PRS 28.5%
-
CSI 0.8rCSI 0.7%PRS 64.5%
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CSI 0.8rCSI 1.5%PRS 31.6%
-
CSI 0.8rCSI 1.4%PRS 49.1%
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CSI 0.8rCSI 0.7%PRS 49.4%
-
CSI 0.8rCSI 1.8%PRS 60.8%
-
CSI 0.8rCSI 1.8%PRS 38.2%
-
CSI 0.8rCSI 3.4%PRS 62.6%
-
CSI 0.9rCSI 3.6%PRS 64.4%
-
CSI 0.9rCSI 1.5%PRS 26.7%
-
CSI 0.9rCSI 1.3%PRS 33.1%
-
CSI 0.9rCSI 1.7%PRS 50.5%
-
CSI 0.9rCSI 0.8%PRS 44.5%
-
CSI 0.9rCSI 1.4%PRS 39.0%
-
CSI 0.9rCSI 2.7%PRS 59.7%
-
CSI 0.9rCSI 1.7%PRS 34.9%
-
CSI 0.9rCSI 1.5%PRS 28.7%
-
CSI 0.9rCSI 2.6%PRS 56.4%
-
CSI 0.9rCSI 1.9%PRS 58.5%
-
CSI 1.0rCSI 3.1%PRS 73.2%
-
CSI 1.0rCSI 1.4%PRS 54.5%
-
CSI 1.0rCSI 3.0%PRS 53.2%
-
CSI 1.0rCSI 2.0%PRS 62.1%
-
CSI 1.0rCSI 1.7%PRS 39.7%
-
CSI 1.0rCSI 1.6%PRS 41.9%
-
CSI 1.0rCSI 1.4%PRS 41.0%
-
CSI 1.0rCSI 1.5%PRS 37.8%
-
CSI 1.0rCSI 2.0%PRS 42.7%
-
CSI 1.0rCSI 6.4%PRS 63.7%
-
CSI 1.0rCSI 2.4%PRS 53.3%
-
CSI 1.0rCSI 2.6%PRS 37.4%
-
CSI 1.0rCSI 2.5%PRS 51.3%
-
CSI 1.0rCSI 1.4%PRS 45.2%
-
CSI 1.0rCSI 1.6%PRS 44.3%
-
CSI 1.0rCSI 2.6%PRS 32.3%
-
CSI 1.1rCSI 3.0%PRS 57.6%
-
CSI 1.1rCSI 1.7%PRS 34.7%
-
CSI 1.1rCSI 4.3%PRS 56.3%
-
CSI 1.1rCSI 1.1%PRS 40.6%
-
CSI 1.1rCSI 26.2%PRS 26.1%
-
CSI 1.1rCSI 2.4%PRS 55.8%
-
CSI 1.1rCSI 3.7%PRS 44.2%
-
CSI 1.1rCSI 1.4%PRS 25.3%
-
CSI 1.1rCSI 1.6%PRS 43.5%
-
CSI 1.2rCSI 3.3%PRS 41.0%
-
CSI 1.2rCSI 1.1%PRS 47.8%
-
CSI 1.2rCSI 2.7%PRS 33.6%
-
CSI 1.2rCSI 2.6%PRS 46.9%
-
CSI 1.2rCSI 2.3%PRS 40.6%
-
CSI 1.2rCSI 1.4%PRS 44.7%
-
CSI 1.2rCSI 4.8%PRS 39.6%
-
CSI 1.2rCSI 2.0%PRS 61.5%
-
CSI 1.2rCSI 1.1%PRS 40.1%
-
CSI 1.2rCSI 1.6%PRS 45.5%
-
CSI 1.2rCSI 1.3%PRS 38.4%
-
CSI 1.2rCSI 1.7%PRS 35.0%
-
CSI 1.2rCSI 1.7%PRS 40.5%
-
CSI 1.3rCSI 2.5%PRS 67.3%
-
CSI 1.3rCSI 1.8%PRS 51.0%
-
CSI 1.3rCSI 2.3%PRS 56.8%
-
CSI 1.3rCSI 1.4%PRS 43.3%
-
CSI 1.3rCSI 1.8%PRS 48.9%
-
CSI 1.3rCSI 1.3%PRS 43.1%
-
CSI 1.3rCSI 1.9%PRS 50.8%
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this specific cell.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Fold Change: Represents the ratio of the current Cell Significance Index to the Cell Significance Index Threshold, indicating how much the gene expression has changed compared to a baseline.
Cell Significance Index: Reflects how strongly a gene is expressed in this cell type. Calculated using techniques like effect size estimation and bootstrapping for reliability.
Network Configuration
Explore relationships of the current gene. Select an Interaction Source: 'ONTOLOGY' for shared pathways (GO/Reactome) or 'STRING' for protein-protein interactions. Further refine by selecting context genes and comparing Cell Significance Index (CSI) scores between baseline and target cell types and their specific contexts.
Comma-separated if multiple.
Comma-separated if multiple.
Legend:
- Query Gene
-
Node Color (Target Cell CSI, relative to current network):
- Very High
- High
- Medium
- Low
- Very Low
- CSI N/A
- Node Size: Proportional to Target Cell CSI magnitude
- STRING PPI Edge
- Shared Pathway Edge (ONTOLOGY)
Other Information
This section provides additional information about the gene, including a description generated by an AI language model and details about associated proteins.
Disclaimer: This in-silico analysis is generated by an AI language model and may contain inaccuracies or hallucinations. However, it is cross-referenced with curated gene expression data from major biological sources. Please verify the information before use.
Genular Protein ID: 3521827145
Symbol: TM50B_HUMAN
Name: Transmembrane protein 50B
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 10077530
Title: Comparative genomic analysis of the interferon/interleukin-10 receptor gene cluster.
PubMed ID: 10077530
PubMed ID: 12975309
Title: The secreted protein discovery initiative (SPDI), a large-scale effort to identify novel human secreted and transmembrane proteins: a bioinformatics assessment.
PubMed ID: 12975309
DOI: 10.1101/gr.1293003
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 17974005
Title: The full-ORF clone resource of the German cDNA consortium.
PubMed ID: 17974005
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 22223895
Title: Comparative large-scale characterisation of plant vs. mammal proteins reveals similar and idiosyncratic N-alpha acetylation features.
PubMed ID: 22223895
Sequence Information:
- Length: 158
- Mass: 17936
- Checksum: 515ABB6AAA817DEB
- Sequence:
MAGFLDNFRW PECECIDWSE RRNAVASVVA GILFFTGWWI MIDAAVVYPK PEQLNHAFHT CGVFSTLAFF MINAVSNAQV RGDSYESGCL GRTGARVWLF IGFMLMFGSL IASMWILFGA YVTQNTDVYP GLAVFFQNAL IFFSTLIYKF GRTEELWT