Details for: CA12
Associated with
Other Information
Genular Protein ID: 4203576834
Symbol: CAH12_HUMAN
Name: Carbonate dehydratase XII
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 9636197
Title: Human carbonic anhydrase XII: cDNA cloning, expression, and chromosomal localization of a carbonic anhydrase gene that is overexpressed in some renal cell cancers.
PubMed ID: 9636197
PubMed ID: 9770531
Title: Down-regulation of transmembrane carbonic anhydrases in renal cell carcinoma cell lines by wild-type von Hippel-Lindau transgenes.
PubMed ID: 9770531
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 15489334
Title: The status, quality, and expansion of the NIH full-length cDNA project: the Mammalian Gene Collection (MGC).
PubMed ID: 15489334
DOI: 10.1101/gr.2596504
PubMed ID: 17705204
Title: Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste.
PubMed ID: 17705204
PubMed ID: 17314045
Title: Phosph(on)ate as a zinc-binding group in metalloenzyme inhibitors: X-ray crystal structure of the antiviral drug foscarnet complexed to human carbonic anhydrase I.
PubMed ID: 17314045
PubMed ID: 17407288
Title: Structural analysis of charge discrimination in the binding of inhibitors to human carbonic anhydrases I and II.
PubMed ID: 17407288
DOI: 10.1021/ja068359w
PubMed ID: 19186056
Title: A thiabendazole sulfonamide shows potent inhibitory activity against mammalian and nematode alpha-carbonic anhydrases.
PubMed ID: 19186056
PubMed ID: 19206230
Title: Non-zinc mediated inhibition of carbonic anhydrases: coumarins are a new class of suicide inhibitors.
PubMed ID: 19206230
DOI: 10.1021/ja809683v
PubMed ID: 18618712
Title: Crystal structure of human carbonic anhydrase XIII and its complex with the inhibitor acetazolamide.
PubMed ID: 18618712
DOI: 10.1002/prot.22144
PubMed ID: 26911677
Title: Loss of carbonic anhydrase XII function in individuals with elevated sweat chloride concentration and pulmonary airway disease.
PubMed ID: 26911677
DOI: 10.1093/hmg/ddw065
PubMed ID: 11493685
Title: Crystal structure of the dimeric extracellular domain of human carbonic anhydrase XII, a bitopic membrane protein overexpressed in certain cancer tumor cells.
PubMed ID: 11493685
PubMed ID: 21035102
Title: Hyperchlorhidrosis caused by homozygous mutation in CA12, encoding carbonic anhydrase XII.
PubMed ID: 21035102
PubMed ID: 21184099
Title: Autosomal recessive hyponatremia due to isolated salt wasting in sweat associated with a mutation in the active site of carbonic cnhydrase 12.
PubMed ID: 21184099
Sequence Information:
- Length: 354
- Mass: 39451
- Checksum: 9016216BF2CA6C0C
- Sequence:
MPRRSLHAAA VLLLVILKEQ PSSPAPVNGS KWTYFGPDGE NSWSKKYPSC GGLLQSPIDL HSDILQYDAS LTPLEFQGYN LSANKQFLLT NNGHSVKLNL PSDMHIQGLQ SRYSATQLHL HWGNPNDPHG SEHTVSGQHF AAELHIVHYN SDLYPDASTA SNKSEGLAVL AVLIEMGSFN PSYDKIFSHL QHVKYKGQEA FVPGFNIEEL LPERTAEYYR YRGSLTTPPC NPTVLWTVFR NPVQISQEQL LALETALYCT HMDDPSPREM INNFRQVQKF DERLVYTSFS QVQVCTAAGL SLGIILSLAL AGILGICIVV VVSIWLFRRK SIKKGDNKGV IYKPATKMET EAHA
Genular Protein ID: 499028068
Symbol: B3KUB4_HUMAN
Name: N/A
UniProtKB Accession Codes:
Database IDs:
Citations:
PubMed ID: 11181995
PubMed ID: 14702039
Title: Complete sequencing and characterization of 21,243 full-length human cDNAs.
PubMed ID: 14702039
DOI: 10.1038/ng1285
PubMed ID: 16572171
Title: Analysis of the DNA sequence and duplication history of human chromosome 15.
PubMed ID: 16572171
DOI: 10.1038/nature04601
Sequence Information:
- Length: 283
- Mass: 31857
- Checksum: F0A4459547CCAF8E
- Sequence:
MPRRSLHAAA VLLLVILKEQ PSSPAPVNGS KWTYFVKLNL PSDMHIQGLQ SRYSATQLHL HWGNPNDPHG SEHTVSGQHF AAELHIVHYN SDLYPDASTA SNKSEGLAVL AVLIEMGSFN PSYDKIFSHL QHVKYKGQEA FVPGFNIEEL LPERTAEYYR YRGSLTTPPC NPTVLWTVFR NPVQISQEQL LALETALYCT HMDDPSPREM INNFRQVQKF DERLVYTSFS QGIILSLALA GILGICIVVV VSIWLFRRKS IKKGDNKGVI YKPATKMETE AHA
Database document:
This is a preview of the gene's schema. Only a few entries are kept for 'singleCellExpressions,' 'mRNAExpressions,' and other large data arrays for visualization purposes. You can zoom in with the mouse wheel for a closer view, and the text will adjust automatically if necessary. For the full schema, download it here.